ARWR (Arrowhead Pharmaceuticals) EBITDA Margin %: -145.59% (As of Mar. 2026)


ARWR Arrowhead Pharmaceuticals Inc ARWR
49 GF Score
Price $81.79
GF Value $52.23
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Arrowhead Pharmaceuticals EBITDA Margin %?

Arrowhead Pharmaceuticals ARWR +2.48% 49 EBITDA Margin % is -145.59% as of Mar. 2026. GuruFocus rates ARWR with a GF Score™ of 49/100 and a GF Value™ of $52.23 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 945 Biotechnology companies, Arrowhead Pharmaceuticals ranks better than 58.84% on this metric.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. Arrowhead Pharmaceuticals's EBITDA for the three months ended in Mar. 2026 was $-107.4 Mil. Arrowhead Pharmaceuticals's Revenue for the three months ended in Mar. 2026 was $73.7 Mil. Therefore, Arrowhead Pharmaceuticals's EBITDA margin for the quarter that ended in Mar. 2026 was -145.59%.


Arrowhead Pharmaceuticals  (NAS:ARWR) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.


Arrowhead Pharmaceuticals EBITDA Margin % Related Terms


Arrowhead Pharmaceuticals EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for Arrowhead Pharmaceuticals's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Arrowhead Pharmaceuticals EBITDA Margin % Chart

Arrowhead Pharmaceuticals Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
EBITDA Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -95.87 -66.72 -72.97 -15,812.81 19.87

Arrowhead Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBITDA Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 73.21 -534.75 25.03 21.65 -145.59

ARWR vs BMRN, MDGL, CYTK: EBITDA Margin % Comparison

For the Biotechnology subindustry, Arrowhead Pharmaceuticals's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Arrowhead Pharmaceuticals EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Arrowhead Pharmaceuticals's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where Arrowhead Pharmaceuticals's EBITDA Margin % falls into.


ARWR
49GF Score
Arrowhead Pharmaceuticals Inc ARWR
EBITDA Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Arrowhead Pharmaceuticals EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

Arrowhead Pharmaceuticals's EBITDA Margin % for the fiscal year that ended in Sep. 2025 is calculated as

EBITDA Margin %=EBITDA (A: Sep. 2025 )/Revenue (A: Sep. 2025 )
=164.822/829.448
=19.87 %

Arrowhead Pharmaceuticals's EBITDA Margin % for the quarter that ended in Mar. 2026 is calculated as

EBITDA Margin %=EBITDA (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-107.351/73.737
=-145.59 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA Margin % →
What does a EBITDA Margin % of -145.59% mean?
Arrowhead Pharmaceuticals (ARWR) has a EBITDA Margin % of -145.59% as of Mar. 2026. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Arrowhead Pharmaceuticals and its competitors. According to the industry distribution chart, Arrowhead Pharmaceuticals ranks #389 out of 945 companies in the Biotechnology industry, placing it in the top 41.2%.
Is Arrowhead Pharmaceuticals' EBITDA Margin % too high?
Arrowhead Pharmaceuticals' current EBITDA Margin % is -145.59%. Based on the distribution chart, Arrowhead Pharmaceuticals ranks #389 out of 945 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Arrowhead Pharmaceuticals has a GF Score™ of 49/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Arrowhead Pharmaceuticals' EBITDA Margin % compare to BMRN and MDGL?
According to the Biotechnology industry distribution chart, Arrowhead Pharmaceuticals ranks #389 out of 945 companies for EBITDA Margin %. This puts Arrowhead Pharmaceuticals in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Arrowhead Pharmaceuticals and its competitors. Arrowhead Pharmaceuticals's current EBITDA Margin % is -145.59%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Arrowhead Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Arrowhead Pharmaceuticals (ARWR) is currently considered Significantly Overvalued. The stock's GF Value™ is $52.23, compared to a current price of $81.79 — trading 56.6% above its estimated fair value. The current EBITDA Margin % is -145.59%. Arrowhead Pharmaceuticals' overall GF Score™ is 49/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Arrowhead Pharmaceuticals (ARWR), the current EBITDA Margin % is -145.59% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Arrowhead Pharmaceuticals (ARWR) Overvalued in 2026?

Based on GuruFocus' analysis, Arrowhead Pharmaceuticals stock appears to be overvalued. The current stock price of $81.79 is trading 56.6% above its estimated GF Value™ of $52.23. GuruFocus considers Arrowhead Pharmaceuticals to be Significantly Overvalued.

Key valuation signals for ARWR:

  • EBITDA Margin %: -145.59%
  • GF Value™: $52.23 vs. price of $81.79 (56.6% above fair value)
  • GF Score™: 49/100 with 6 warning signs

No single metric tells the full story. See the ARWR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Arrowhead Pharmaceuticals Business Description

Address 177 E Colorado Boulevard, Suite 700, Pasadena, CA, USA, 91105
Arrowhead Pharmaceuticals Inc is a commercial-stage pharmaceutical company. It is focused on the development of medicines for diseases associated with genetic abnormalities or protein overproduction. The company develops potential RNAi therapies designed to inhibit the expression of genes known to trigger diseases. Its portfolio includes potential drugs targeting Cardiometabolic, Neuromuscular, Pulmonary, Liver, and other diseases. The company also develops RNAi products and clinical candidates designed to target different cell types within the body.
49GF Score

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EBITDA Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$81.79
Price
$52.23
GF Value