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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Arrowhead Pharmaceuticals's enterprise value is $11,489.9 Mil.
Arrowhead Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-134.5 Mil. Therefore, Arrowhead Pharmaceuticals's EV-to-EBITDA for today is -85.45.
The historical rank and industry rank for Arrowhead Pharmaceuticals's EV-to-EBITDA or its related term are showing as below:
ARWR'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -167.89 Med: -15.8 Max: 700.67
Current: -85.45
During the past 13 years, the highest EV-to-EBITDA of Arrowhead Pharmaceuticals was 700.67. The lowest was -167.89. And the median was -15.80.
ARWR's EV-to-EBITDA is ranked worse than 100% of 410
companies
in the Biotechnology industry
Industry Median: 11.46
vs ARWR: -85.45
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Arrowhead Pharmaceuticals's PE Ratio (TTM) for today is calculated as:
Arrowhead Pharmaceuticals's share price for today is $87.32.
Arrowhead Pharmaceuticals's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.150.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Arrowhead Pharmaceuticals's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Arrowhead Pharmaceuticals EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Arrowhead Pharmaceuticals's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Arrowhead Pharmaceuticals's EV-to-EBITDA falls into.
Arrowhead Pharmaceuticals's current Enterprise Value is $11,489.9 Mil.
Arrowhead Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-134.5 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Arrowhead Pharmaceuticals (ARWR) has a EV-to-EBITDA of -85.45 as of Jul. 30, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Arrowhead Pharmaceuticals. According to the industry distribution chart, Arrowhead Pharmaceuticals ranks #999999 out of 410 companies in the Biotechnology industry.
Is Arrowhead Pharmaceuticals' EV-to-EBITDA too high?
Arrowhead Pharmaceuticals' current EV-to-EBITDA is -85.45. Based on the distribution chart, Arrowhead Pharmaceuticals ranks #999999 out of 410 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Arrowhead Pharmaceuticals has a GF Score™ of 40/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Arrowhead Pharmaceuticals' EV-to-EBITDA compare to AXSM and MDGL?
According to the Biotechnology industry distribution chart, Arrowhead Pharmaceuticals ranks #999999 out of 410 companies for EV-to-EBITDA. This places Arrowhead Pharmaceuticals in the lower half of its industry. The industry median EV-to-EBITDA is 11.46. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 11.46, based on 410 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Arrowhead Pharmaceuticals. For the Biotechnology industry, the median EV-to-EBITDA is 11.46 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Arrowhead Pharmaceuticals's current EV-to-EBITDA is -85.45. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Arrowhead Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Arrowhead Pharmaceuticals (ARWR) is currently considered Significantly Overvalued. The stock's GF Value™ is $49.26, compared to a current price of $87.32 — trading 77.3% above its estimated fair value. The current EV-to-EBITDA is -85.45. Arrowhead Pharmaceuticals' overall GF Score™ is 40/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Arrowhead Pharmaceuticals (ARWR), the current EV-to-EBITDA is -85.45 as of Jul. 30, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Arrowhead Pharmaceuticals (ARWR) Overvalued in 2026?
Based on GuruFocus' analysis, Arrowhead Pharmaceuticals stock appears to be overvalued.
The current stock price of $87.32 is trading 77.3% above its estimated GF Value™ of $49.26.
GuruFocus considers Arrowhead Pharmaceuticals to be Significantly Overvalued.
Key valuation signals for ARWR:
EV-to-EBITDA: -85.45
GF Value™: $49.26 vs. price of $87.32 (77.3% above fair value)
No single metric tells the full story. See the ARWR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Arrowhead Pharmaceuticals Inc is a commercial-stage pharmaceutical company. It is focused on the development of medicines for diseases associated with genetic abnormalities or protein overproduction. The company develops potential RNAi therapies designed to inhibit the expression of genes known to trigger diseases. Its portfolio includes potential drugs targeting Cardiometabolic, Neuromuscular, Pulmonary, Liver, and other diseases. The company also develops RNAi products and clinical candidates designed to target different cell types within the body.
40GF Score
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