Arrowhead PharmaceuticalsARWR -1.63%49 Median PS Value is $127.14 as of Jun. 25, 2026, which is 50756% above its 10-year median of 0.25. GuruFocus rates ARWR with a GF Score™ of 49/100 and a GF Value™ of $52.23 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 277 Biotechnology companies, Arrowhead Pharmaceuticals ranks better than 50.18% on this metric.
This valuation method assumes that the stock valuation will revert to its historical (10-Year) median in terms of PS Ratio. The reason we use PS Ratio instead of PE Ratio or PB Ratio is because PS Ratio is independent of profit margin, and can be applied to a broader range of situations.
The historical rank and industry rank for Arrowhead Pharmaceuticals's Median PS Value or its related term are showing as below:
ARWR'
s Price-to-Median-PS-Value Range Over the Past 10 Years
Min: 0.04 Med: 0.25 Max: 25.75
Current: 0.62
During the past 13 years, the highest Price to Median PS Value of Arrowhead Pharmaceuticals was 25.75. The lowest was 0.04. And the median was 0.25.
ARWR's Price-to-Median-PS-Value is ranked better than 50.18% of 277
companies
in the Biotechnology industry
Industry Median: 0.63
vs ARWR: 0.62
Arrowhead Pharmaceuticals (NAS:ARWR) Median PS Value Explanation
This valuation method assumes that the stock valuation will revert to its historical (10-Year) mean in terms of PS Ratio. The reason we use PS Ratio instead of PE Ratio or PB Ratio
is because PS Ratio is independent of profit margin, and can be applied to a broader range of situations.
It also assumes that over time the profit margin is constant. If a company increases its profit margin to a sustainable level, this value might under-estimate its value. If it has permanent declined profit margins, this may over-estimate the company's value.
Arrowhead Pharmaceuticals's Price to Median PS Value for today is calculated as
Price to Median PS Value
=
Share Price
/
Median PS Value
=
78.51
/
127.14
=
0.62
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Arrowhead Pharmaceuticals Median PS Value Related Terms
Arrowhead Pharmaceuticals Median PS Value Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ARWR vs BMRN, MDGL, CYTK: Median PS Value Comparison
For the Biotechnology subindustry, Arrowhead Pharmaceuticals's Price-to-Median-PS-Value, along with its competitors' market caps and Price-to-Median-PS-Value data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Arrowhead Pharmaceuticals Price-to-Median-PS-Value vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Arrowhead Pharmaceuticals's Price-to-Median-PS-Value distribution charts can be found below:
* The bar in red indicates where Arrowhead Pharmaceuticals's Price-to-Median-PS-Value falls into.
10-Year Median PS Ratio is 28.5451.
Arrowhead Pharmaceuticals's Revenue per Share for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $4.454.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Arrowhead Pharmaceuticals (ARWR) has a Median PS Value of $127.14 as of Jun. 25, 2026. Median price-sales value is the stock value based on a company's 10-year median price-sales ratio, View historical data on Arrowhead Pharmaceuticals and its competitors. This is 50756% above median its historical median of 0.25. Over the past decade, Arrowhead Pharmaceuticals' Median PS Value has ranged from 0.04 to 25.75. According to the industry distribution chart, Arrowhead Pharmaceuticals ranks #138 out of 277 companies in the Biotechnology industry, placing it in the top 49.8%.
Is Arrowhead Pharmaceuticals' Median PS Value too high?
Arrowhead Pharmaceuticals' current Median PS Value of $127.14 is 50756% above median its 10-year median of 0.25. Over the past 10 years, this metric has ranged from a low of 0.04 to a high of 25.75. The Biotechnology industry median Median PS Value is 0.63. Arrowhead Pharmaceuticals' value of $127.14 is 20081% above this industry median. Based on the distribution chart, Arrowhead Pharmaceuticals ranks #138 out of 277 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Arrowhead Pharmaceuticals has a GF Score™ of 49/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Arrowhead Pharmaceuticals' Median PS Value compare to BMRN and MDGL?
According to the Biotechnology industry distribution chart, Arrowhead Pharmaceuticals ranks #138 out of 277 companies for Median PS Value. This puts Arrowhead Pharmaceuticals in the upper half of its industry. The industry median Median PS Value is 0.63. Arrowhead Pharmaceuticals' value of $127.14 is 20081% above this benchmark. Historically, Arrowhead Pharmaceuticals' own Median PS Value has ranged from 0.04 to 25.75 over the past decade. While the company's 10-year median is 0.25 vs. the industry median of 0.63, Arrowhead Pharmaceuticals has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Median PS Value for a Biotechnology company?
The median Median PS Value among Biotechnology companies is 0.63, based on 277 companies in the industry. Companies in the top quartile (top 25%) have a Median PS Value significantly above this median, while those in the bottom quartile fall well below. However, Median PS Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Arrowhead Pharmaceuticals's current Median PS Value of $127.14 is 20081% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Median PS Value mean?
A high Median PS Value can signal that a stock is expensive relative to its fundamentals. Median price-sales value is the stock value based on a company's 10-year median price-sales ratio, View historical data on Arrowhead Pharmaceuticals and its competitors. For the Biotechnology industry, the median Median PS Value is 0.63 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Arrowhead Pharmaceuticals's current Median PS Value is $127.14, which is 50756% above median its own 10-year median of 0.25. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Arrowhead Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Arrowhead Pharmaceuticals (ARWR) is currently considered Significantly Overvalued. The stock's GF Value™ is $52.23, compared to a current price of $78.51 — trading 50.3% above its estimated fair value. The current Median PS Value is $127.14, which is 50756% above median its 10-year median of 0.25 and 20081% above the Biotechnology industry median of 0.63. Arrowhead Pharmaceuticals' overall GF Score™ is 49/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Median PS Value calculated?
Median PS Value is calculated from a company's financial statements. For Arrowhead Pharmaceuticals (ARWR), the current Median PS Value is $127.14 as of Jun. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Arrowhead Pharmaceuticals (ARWR) Overvalued in 2026?
Based on GuruFocus' analysis, Arrowhead Pharmaceuticals stock appears to be overvalued.
The current stock price of $78.51 is trading 50.3% above its estimated GF Value™ of $52.23.
GuruFocus considers Arrowhead Pharmaceuticals to be Significantly Overvalued.
Key valuation signals for ARWR:
Median PS Value: $127.14 (50756% above median its 10-year median of 0.25)
GF Value™: $52.23 vs. price of $78.51 (50.3% above fair value)
Industry Position: 20081% above the Biotechnology median (#138 of 277)
No single metric tells the full story. See the ARWR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Arrowhead Pharmaceuticals Inc is a commercial-stage pharmaceutical company. It is focused on the development of medicines for diseases associated with genetic abnormalities or protein overproduction. The company develops potential RNAi therapies designed to inhibit the expression of genes known to trigger diseases. Its portfolio includes potential drugs targeting Cardiometabolic, Neuromuscular, Pulmonary, Liver, and other diseases. The company also develops RNAi products and clinical candidates designed to target different cell types within the body.
49GF Score
Get the complete analysis for ARWR
Median PS Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
ARWR has been successfully added to your 
