ZYME (Zymeworks) Debt-to-EBITDA : (As of Jun. 2026)

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ZYME Zymeworks Inc ZYME
63 GF Score
Price $26.81
GF Value $27.44
Valuation Fairly Valued
! 4 Warning Signs
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What is Zymeworks Debt-to-EBITDA?

Debt-to-EBITDA measures a company's ability to pay off its debt.

Zymeworks's Short-Term Debt & Capital Lease Obligation for the quarter that ended in Jun. 2026 was $3.30 Mil. Zymeworks's Long-Term Debt & Capital Lease Obligation for the quarter that ended in Jun. 2026 was $265.33 Mil. Zymeworks's annualized EBITDA for the quarter that ended in Jun. 2026 was $-146.97 Mil. Zymeworks's annualized Debt-to-EBITDA for the quarter that ended in Jun. 2026 was -1.83.

A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt. According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.

The historical rank and industry rank for Zymeworks's Debt-to-EBITDA or its related term are showing as below:

ZYME' s Debt-to-EBITDA Range Over the Past 10 Years
Min: -0.22   Med: -0.09   Max: 0.2
Current: -0.12

During the past 12 years, the highest Debt-to-EBITDA Ratio of Zymeworks was 0.20. The lowest was -0.22. And the median was -0.09.

ZYME's Debt-to-EBITDA is ranked worse than
100% of 304 companies
in the Biotechnology industry
Industry Median: 1.215 vs ZYME: -0.12

Zymeworks  (NAS:ZYME) Debt-to-EBITDA Explanation

In the calculation of Debt-to-EBITDA, we use the total of Short-Term Debt & Capital Lease Obligation and Long-Term Debt & Capital Lease Obligation divided by EBITDA. In some calculations, Total Liabilities is used to for calculation.


Be Aware

A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt.

According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.


Zymeworks Debt-to-EBITDA Related Terms


Zymeworks Debt-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Zymeworks's Debt-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zymeworks Debt-to-EBITDA Chart

Zymeworks Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Debt-to-EBITDA
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Zymeworks Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
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ZYME vs ZBIO, STOK, AGIO: Debt-to-EBITDA Comparison

For the Biotechnology subindustry, Zymeworks's Debt-to-EBITDA, along with its competitors' market caps and Debt-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Zymeworks Debt-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Zymeworks's Debt-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Zymeworks's Debt-to-EBITDA falls into.


ZYME
63GF Score
Zymeworks Inc ZYME
Debt-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Zymeworks Debt-to-EBITDA Calculation

Debt-to-EBITDA measures a company's ability to pay off its debt.

Zymeworks's Debt-to-EBITDA for the fiscal year that ended in Dec. 2025 is calculated as

Debt-to-EBITDA=Total Debt / EBITDA
=(Short-Term Debt & Capital Lease Obligation + Long-Term Debt & Capital Lease Obligation) / EBITDA
=(3.471 + 14.796) / -68.960000000074
=-0.26

Zymeworks's annualized Debt-to-EBITDA for the quarter that ended in Jun. 2026 is calculated as

Debt-to-EBITDA=Total Debt / EBITDA
=(Short-Term Debt & Capital Lease Obligation + Long-Term Debt & Capital Lease Obligation) / EBITDA
=(3.304 + 265.334) / -146.97200000096
=-1.83

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Debt-to-EBITDA, the EBITDA of the last fiscal year is used. In calculating the annualized quarterly data, the EBITDA data used here is four times the quarterly (Jun. 2026) EBITDA data.

Is Zymeworks (ZYME) Overvalued in 2026?

Based on GuruFocus' analysis, Zymeworks stock appears to be undervalued. The current stock price of $26.81 is trading 2.3% below its estimated GF Value™ of $27.44. GuruFocus considers Zymeworks to be Fairly Valued.

Key valuation signals for ZYME:

  • Debt-to-EBITDA:
  • GF Value™: $27.44 vs. price of $26.81 (2.3% below fair value)
  • GF Score™: 63/100 with 4 warning signs

No single metric tells the full story. See the ZYME stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Zymeworks Business Description

Other Exchanges ZA8:Germany
Address 108 Patriot Drive, Suite A, Middletown, DE, USA, 19709
Zymeworks Inc is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics. Its suite of therapeutic platforms and its fully integrated drug development engine enables precise engineering of differentiated therapeutic product candidates. Its clinical candidate, zanidatamab, is a novel HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. It is also advancing a deep preclinical pipeline in oncology and other therapeutic areas.
63GF Score

Get the complete analysis for ZYME

Debt-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$26.81
Price
$27.44
GF Value