ZYME (Zymeworks) FCF Margin %: -1,907.56% (As of Mar. 2026)


ZYME Zymeworks Inc ZYME
66 GF Score
Price $24.31
GF Value $22.11
Valuation Fairly Valued
! 2 Warning Signs
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What is Zymeworks FCF Margin %?

Zymeworks ZYME +1.76% 66 FCF Margin % is -1,907.56% as of Mar. 2026. GuruFocus rates ZYME with a GF Score™ of 66/100 and a GF Value™ of $22.11 (Fairly Valued). The stock has 2 warning signs investors should review. Among 959 Biotechnology companies, Zymeworks ranks worse than 51.82% on this metric.

FCF Margin % is calculated as Free Cash Flow divided by its Revenue. Zymeworks's Free Cash Flow for the three months ended in Mar. 2026 was $-45.93 Mil. Zymeworks's Revenue for the three months ended in Mar. 2026 was $2.41 Mil. Therefore, Zymeworks's FCF Margin % for the quarter that ended in Mar. 2026 was -1,907.56%.

As of today, Zymeworks's current FCF Yield % is -4.34%.

The historical rank and industry rank for Zymeworks's FCF Margin % or its related term are showing as below:

ZYME' s FCF Margin % Range Over the Past 10 Years
Min: -771.12   Med: -154.64   Max: 39.15
Current: -95.43


During the past 12 years, the highest FCF Margin % of Zymeworks was 39.15%. The lowest was -771.12%. And the median was -154.64%.

ZYME's FCF Margin % is ranked worse than
51.82% of 959 companies
in the Biotechnology industry
Industry Median: -84.65 vs ZYME: -95.43


Zymeworks FCF Margin % Related Terms


Zymeworks FCF Margin % Historical Data

* Premium members only.

The historical data trend for Zymeworks's FCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zymeworks FCF Margin % Chart

Zymeworks Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
FCF Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -771.12 31.76 -161.03 -148.25 -33.37

Zymeworks Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
FCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -13.81 22.96 -115.24 -436.54 -1,907.56

ZYME vs ADMA, NRIX, IOVA: FCF Margin % Comparison

For the Biotechnology subindustry, Zymeworks's FCF Margin %, along with its competitors' market caps and FCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Zymeworks FCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Zymeworks's FCF Margin % distribution charts can be found below:

* The bar in red indicates where Zymeworks's FCF Margin % falls into.


ZYME
66GF Score
Zymeworks Inc ZYME
FCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Zymeworks FCF Margin % Calculation

FCF margin is the ratio of Free Cash Flow divided by net sales or Revenue, usually presented in percent.

Zymeworks's FCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

FCF Margin=Free Cash Flow (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-35.357/105.965
=-33.37 %

Zymeworks's FCF Margin for the quarter that ended in Mar. 2026 is calculated as

FCF Margin=Free Cash Flow (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-45.934/2.408
=-1,907.56 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about FCF Margin % →
What does a FCF Margin % of -1,907.56% mean?
Zymeworks (ZYME) has a FCF Margin % of -1,907.56% as of Mar. 2026. Free cash flow margin is the ratio of total free cash flow to net sales. View historical data on Zymeworks and its competitors. According to the industry distribution chart, Zymeworks ranks #497 out of 959 companies in the Biotechnology industry, placing it in the top 51.8%.
Is Zymeworks' FCF Margin % too high?
Zymeworks' current FCF Margin % is -1,907.56%. Based on the distribution chart, Zymeworks ranks #497 out of 959 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Zymeworks has a GF Score™ of 66/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Zymeworks' FCF Margin % compare to ADMA and NRIX?
According to the Biotechnology industry distribution chart, Zymeworks ranks #497 out of 959 companies for FCF Margin %. This places Zymeworks in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good FCF Margin % for a Biotechnology company?
A good FCF Margin % depends on the Biotechnology industry context. However, FCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high FCF Margin % mean?
A high FCF Margin % can signal that a stock is expensive relative to its fundamentals. Free cash flow margin is the ratio of total free cash flow to net sales. View historical data on Zymeworks and its competitors. Zymeworks's current FCF Margin % is -1,907.56%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zymeworks stock overvalued right now?
Based on GuruFocus' analysis, Zymeworks (ZYME) is currently considered Fairly Valued. The stock's GF Value™ is $22.11, compared to a current price of $24.31 — trading 10% above its estimated fair value. The current FCF Margin % is -1,907.56%. Zymeworks' overall GF Score™ is 66/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is FCF Margin % calculated?
FCF Margin % is calculated from a company's financial statements. For Zymeworks (ZYME), the current FCF Margin % is -1,907.56% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Zymeworks (ZYME) Overvalued in 2026?

Based on GuruFocus' analysis, Zymeworks stock appears to be overvalued. The current stock price of $24.31 is trading 10% above its estimated GF Value™ of $22.11. GuruFocus considers Zymeworks to be Fairly Valued.

Key valuation signals for ZYME:

  • FCF Margin %: -1,907.56%
  • GF Value™: $22.11 vs. price of $24.31 (10% above fair value)
  • GF Score™: 66/100 with 2 warning signs

No single metric tells the full story. See the ZYME stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Zymeworks Business Description

Other Exchanges ZA8:Germany
Address 108 Patriot Drive, Suite A, Middletown, DE, USA, 19709
Zymeworks Inc is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics. Its suite of therapeutic platforms and its fully integrated drug development engine enables precise engineering of differentiated therapeutic product candidates. Its clinical candidate, zanidatamab, is a novel HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. It is also advancing a deep preclinical pipeline in oncology and other therapeutic areas.
66GF Score

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FCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$24.31
Price
$22.11
GF Value