Think of Enterprise Value as the theoretical takeover price. It is more comprehensive than market capitalization (Market Cap), which only includes common equity. Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.
EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Zymeworks's Enterprise Value is $1,427.65 Mil.
Zymeworks's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-111.09 Mil. Therefore, Zymeworks's EV-to-EBIT ratio for today is -12.85.
EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA. As of today, Zymeworks's Enterprise Value is $1,427.65 Mil.
Zymeworks's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-100.44 Mil. Therefore, Zymeworks's EV-to-EBITDA ratio for today is -14.21.
EV-to-Revenue is calculated as Enterprise Value divided by its Revenue. As of today, Zymeworks's Enterprise Value is $1,427.65 Mil.
Zymeworks's Revenue for the trailing twelve months (TTM) ended in Mar. 2026 was $81.26 Mil. Therefore, Zymeworks's EV-to-Revenue ratio for today is 17.57.
EV-to-FCF is calculated as Enterprise Value divided by its Free Cash Flow. As of today, Zymeworks's Enterprise Value is $1,427.65 Mil.
Zymeworks's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was $-77.55 Mil. Therefore, Zymeworks's EV-to-FCF ratio for today is -18.41.
*** Please note that the current Enterprise Value is calculated using the current market capitalization and the most recently available financial data. If key financial fields—Long-Term Debt & Capital Lease Obligation and Short-Term Debt & Capital Lease Obligation—are recorded as null in the latest reporting period, our data vendor will default to using data from the prior period with valid entries.
Zymeworks (NAS:ZYME) Enterprise Value Explanation
When an investor buy a company, the investor needs to pay not only the common shares, he/she also needs to pay the shareholders of Preferred Stocks. He also assumes the debt of the company, and receives the cash on the company's balance sheet.
If a company has more cash than debt, the investor actually pays less than the Market Cap because he immediately owns the cash once the transaction goes through.
The market value of Preferred Stock needs to be added to the market value of common stocks in the calculation of Enterprise Value.
For the companies with the same Market Cap, the smaller the Enterprise Value is, the cheaper the company is.
Enterprise Value can be negative when the company's net cash is more than its Market Cap. In this case the investor is basically getting the company for free and get paid for that.
1. EV-to-EBIT is calculated as Enterprise Value divided by its EBIT.
Zymeworks's current Enterprise Value is $1,427.65 Mil.
Zymeworks's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-111.09 Mil.
2. EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA.
Zymeworks's current Enterprise Value is $1,427.65 Mil.
Zymeworks's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-100.44 Mil.
Zymeworks's current Enterprise Value is $1,427.65 Mil.
Zymeworks's Revenue for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $81.26 Mil.
Zymeworks's current Enterprise Value is $1,427.65 Mil.
Zymeworks's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-75.32 Mil.
Zymeworks's current Enterprise Value is $1,427.65 Mil.
Zymeworks's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-77.55 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Zymeworks Enterprise Value Related Terms
Zymeworks Enterprise Value Historical Data
* Premium members only.
The historical data trend for Zymeworks's Enterprise Value can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ZYME vs SRPT, BCAX, INVA: Enterprise Value Comparison
For the Biotechnology subindustry, Zymeworks's Enterprise Value, along with its competitors' market caps and Enterprise Value data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Zymeworks Enterprise Value vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Zymeworks's Enterprise Value distribution charts can be found below:
* The bar in red indicates where Zymeworks's Enterprise Value falls into.
Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.
Zymeworks's Enterprise Value for the fiscal year that ended in Dec. 2025 is calculated as
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
What does a Enterprise Value of $1,427.65 Mil mean?
Zymeworks (ZYME) has a Enterprise Value of $1,427.65 Mil as of Jun. 28, 2026. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Zymeworks and its competitors.
Is Zymeworks' Enterprise Value too high?
Zymeworks' current Enterprise Value is $1,427.65 Mil. Overall, Zymeworks has a GF Score™ of 66/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Zymeworks' Enterprise Value compare to SRPT and BCAX?
Zymeworks' Enterprise Value of $1,427.65 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Enterprise Value for a Biotechnology company?
A good Enterprise Value depends on the Biotechnology industry context. However, Enterprise Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Enterprise Value mean?
A high Enterprise Value can signal that a stock is expensive relative to its fundamentals. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Zymeworks and its competitors. Zymeworks's current Enterprise Value is $1,427.65 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zymeworks stock overvalued right now?
Based on GuruFocus' analysis, Zymeworks (ZYME) is currently considered Fairly Valued. The stock's GF Value™ is $22.34, compared to a current price of $24.13 — trading 8% above its estimated fair value. The current Enterprise Value is $1,427.65 Mil. Zymeworks' overall GF Score™ is 66/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Enterprise Value calculated?
Enterprise Value is calculated from a company's financial statements. For Zymeworks (ZYME), the current Enterprise Value is $1,427.65 Mil as of Jun. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Zymeworks (ZYME) Overvalued in 2026?
Based on GuruFocus' analysis, Zymeworks stock appears to be overvalued.
The current stock price of $24.13 is trading 8% above its estimated GF Value™ of $22.34.
GuruFocus considers Zymeworks to be Fairly Valued.
Key valuation signals for ZYME:
Enterprise Value: $1,427.65 Mil
GF Value™: $22.34 vs. price of $24.13 (8% above fair value)
No single metric tells the full story. See the ZYME stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Zymeworks Inc is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics. Its suite of therapeutic platforms and its fully integrated drug development engine enables precise engineering of differentiated therapeutic product candidates. Its clinical candidate, zanidatamab, is a novel HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. It is also advancing a deep preclinical pipeline in oncology and other therapeutic areas.
66GF Score
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