ZymeworksZYME +1.77%66 OCF Margin % is -1,898.59% as of Mar. 2026. GuruFocus rates ZYME with a GF Score™ of 66/100 and a GF Value™ of $22.22 (Modestly Overvalued). The stock has 2 warning signs investors should review. Among 960 Biotechnology companies, Zymeworks ranks worse than 52.81% on this metric.
The historical rank and industry rank for Zymeworks's OCF Margin % or its related term are showing as below:
ZYME'
s OCF Margin % Range Over the Past 10 Years
Min: -721.33 Med: -149.95 Max: 45.6
Current: -92.68
During the past 12 years, the highest OCF Margin % of Zymeworks was 45.60%. The lowest was -721.33%. And the median was -149.95%.
ZYME's OCF Margin % is ranked worse than 52.81% of 960
companies
in the Biotechnology industry
Industry Median: -68.59
vs ZYME: -92.68
Zymeworks OCF Margin % Related Terms
Zymeworks OCF Margin % Historical Data
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The historical data trend for Zymeworks's OCF Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Zymeworks's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Zymeworks OCF Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Zymeworks's OCF Margin % distribution charts can be found below:
* The bar in red indicates where Zymeworks's OCF Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Zymeworks (ZYME) has a OCF Margin % of -1,898.59% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Zymeworks and its competitors. According to the industry distribution chart, Zymeworks ranks #507 out of 960 companies in the Biotechnology industry, placing it in the top 52.8%.
Is Zymeworks' OCF Margin % too high?
Zymeworks' current OCF Margin % is -1,898.59%. Based on the distribution chart, Zymeworks ranks #507 out of 960 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Zymeworks has a GF Score™ of 66/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Zymeworks' OCF Margin % compare to ADMA and NRIX?
According to the Biotechnology industry distribution chart, Zymeworks ranks #507 out of 960 companies for OCF Margin %. This places Zymeworks in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Zymeworks and its competitors. Zymeworks's current OCF Margin % is -1,898.59%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zymeworks stock overvalued right now?
Based on GuruFocus' analysis, Zymeworks (ZYME) is currently considered Modestly Overvalued. The stock's GF Value™ is $22.22, compared to a current price of $24.74 — trading 11.3% above its estimated fair value. The current OCF Margin % is -1,898.59%. Zymeworks' overall GF Score™ is 66/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For Zymeworks (ZYME), the current OCF Margin % is -1,898.59% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Zymeworks (ZYME) Overvalued in 2026?
Based on GuruFocus' analysis, Zymeworks stock appears to be overvalued.
The current stock price of $24.74 is trading 11.3% above its estimated GF Value™ of $22.22.
GuruFocus considers Zymeworks to be Modestly Overvalued.
Key valuation signals for ZYME:
OCF Margin %: -1,898.59%
GF Value™: $22.22 vs. price of $24.74 (11.3% above fair value)
No single metric tells the full story. See the ZYME stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Zymeworks Inc is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics. Its suite of therapeutic platforms and its fully integrated drug development engine enables precise engineering of differentiated therapeutic product candidates. Its clinical candidate, zanidatamab, is a novel HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. It is also advancing a deep preclinical pipeline in oncology and other therapeutic areas.
66GF Score
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