Net margin is calculated as Net Income divided by its Revenue. Zymeworks's Net Income for the
three
months ended in Mar. 2026 was $-44.16 Mil. Zymeworks's Revenue for the
three
months ended in Mar. 2026 was $2.41 Mil. Therefore, Zymeworks's net margin for the quarter that ended in Mar. 2026 was -1,833.97%.
The historical rank and industry rank for Zymeworks's Net Margin % or its related term are showing as below:
ZYME'
s Net Margin % Range Over the Past 10 Years
Min: -794.01 Med: -158.47 Max: 30.14
Current: -126.33
ZYME's Net Margin % is ranked worse than 53.64% of 947
companies
in the Biotechnology industry
Industry Median: -89.56
vs ZYME: -126.33
Zymeworks (NAS:ZYME) Net Margin % Explanation
Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.
But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.
Zymeworks Net Margin % Related Terms
Zymeworks Net Margin % Historical Data
* Premium members only.
The historical data trend for Zymeworks's Net Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Zymeworks's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Zymeworks Net Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Zymeworks's Net Margin % distribution charts can be found below:
* The bar in red indicates where Zymeworks's Net Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Zymeworks (ZYME) has a Net Margin % of -1,833.97% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Zymeworks and its competitors. According to the industry distribution chart, Zymeworks ranks #508 out of 947 companies in the Biotechnology industry, placing it in the top 53.6%.
Is Zymeworks' Net Margin % too high?
Zymeworks' current Net Margin % is -1,833.97%. Based on the distribution chart, Zymeworks ranks #508 out of 947 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Zymeworks has a GF Score™ of 66/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Zymeworks' Net Margin % compare to ADMA and NRIX?
According to the Biotechnology industry distribution chart, Zymeworks ranks #508 out of 947 companies for Net Margin %. This places Zymeworks in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Zymeworks and its competitors. Zymeworks's current Net Margin % is -1,833.97%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zymeworks stock overvalued right now?
Based on GuruFocus' analysis, Zymeworks (ZYME) is currently considered Fairly Valued. The stock's GF Value™ is $22.11, compared to a current price of $24.30 — trading 9.9% above its estimated fair value. The current Net Margin % is -1,833.97%. Zymeworks' overall GF Score™ is 66/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Zymeworks (ZYME), the current Net Margin % is -1,833.97% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Zymeworks (ZYME) Overvalued in 2026?
Based on GuruFocus' analysis, Zymeworks stock appears to be overvalued.
The current stock price of $24.30 is trading 9.9% above its estimated GF Value™ of $22.11.
GuruFocus considers Zymeworks to be Fairly Valued.
Key valuation signals for ZYME:
Net Margin %: -1,833.97%
GF Value™: $22.11 vs. price of $24.30 (9.9% above fair value)
No single metric tells the full story. See the ZYME stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Zymeworks Inc is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics. Its suite of therapeutic platforms and its fully integrated drug development engine enables precise engineering of differentiated therapeutic product candidates. Its clinical candidate, zanidatamab, is a novel HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. It is also advancing a deep preclinical pipeline in oncology and other therapeutic areas.
66GF Score
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