DYAI (Dyadic International) E10: $-0.30 (As of Mar. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

DYAI Dyadic International Inc DYAI
37 GF Score
Price $1.47
GF Value $0.74
Valuation Significantly Overvalued
! 7 Warning Signs
View Full Analysis

What is Dyadic International E10?

Dyadic International DYAI +21.49% 37 E10 is $-0.30 as of Mar. 2026. GuruFocus rates DYAI with a GF Score™ of 37/100 and a GF Value™ of $0.74 (Significantly Overvalued). The stock has 7 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Dyadic International's adjusted earnings per share data for the three months ended in Mar. 2026 was $-0.050. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-0.30 for the trailing ten years ended in Mar. 2026.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-07-21), Dyadic International's current stock price is $1.47. Dyadic International's E10 for the quarter that ended in Mar. 2026 was $-0.30. Dyadic International's Shiller PE Ratio of today is .

During the past 13 years, the highest Shiller PE Ratio of Dyadic International was 777.00. The lowest was 30.50. And the median was 170.00.


Dyadic International  (NAS:DYAI) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

During the past 13 years, the highest Shiller P/E Ratio of Dyadic International was 777.00. The lowest was 30.50. And the median was 170.00.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Dyadic International E10 Related Terms


Dyadic International E10 Historical Data

* Premium members only.

The historical data trend for Dyadic International's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Dyadic International E10 Chart

Dyadic International Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.03 0.02 -0.01 -0.01 -0.30

Dyadic International Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.01 -0.02 -0.03 -0.30 -0.30

DYAI vs GRDX, TVGN, KYNB: E10 Comparison

For the Biotechnology subindustry, Dyadic International's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Dyadic International Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Dyadic International's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Dyadic International's Shiller PE Ratio falls into.


DYAI
37GF Score
Dyadic International Inc DYAI
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Dyadic International E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Dyadic International's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.05/330.2130*330.2130
=-0.050

Current CPI (Mar. 2026) = 330.2130.

Dyadic International Quarterly Data

per share eps CPI Adj_EPS
201606 0.010 241.018 0.014
201609 -0.030 241.428 -0.041
201612 -0.060 241.432 -0.082
201703 0.070 243.801 0.095
201706 -0.050 244.955 -0.067
201709 -0.050 246.819 -0.067
201712 -0.040 246.524 -0.054
201803 -0.070 249.554 -0.093
201806 -0.060 251.989 -0.079
201809 -0.060 252.439 -0.078
201812 -0.020 251.233 -0.026
201903 -0.080 254.202 -0.104
201906 -0.100 256.143 -0.129
201909 -0.060 256.759 -0.077
201912 -0.070 256.974 -0.090
202003 -0.080 258.115 -0.102
202006 -0.100 257.797 -0.128
202009 -0.090 260.280 -0.114
202012 -0.070 260.474 -0.089
202103 -0.120 264.877 -0.150
202106 -0.140 271.696 -0.170
202109 -0.060 274.310 -0.072
202112 -0.150 278.802 -0.178
202203 -0.090 287.504 -0.103
202206 -0.120 296.311 -0.134
202209 -0.060 296.808 -0.067
202212 -0.070 296.797 -0.078
202303 -0.030 301.836 -0.033
202306 -0.070 305.109 -0.076
202309 -0.060 307.789 -0.064
202312 -0.080 306.746 -0.086
202403 -0.070 312.332 -0.074
202406 -0.070 314.175 -0.074
202409 -0.010 315.301 -0.010
202412 -0.050 315.605 -0.052
202503 -0.070 319.799 -0.072
202506 -0.060 322.561 -0.061
202509 -0.060 324.800 -0.061
202512 -0.060 324.054 -0.061
202603 -0.050 330.213 -0.050

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-0.30 mean?
Dyadic International (DYAI) has a E10 of $-0.30 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Dyadic International and its competitors.
Is Dyadic International's E10 too high?
Dyadic International's current E10 is $-0.30. Overall, Dyadic International has a GF Score™ of 37/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Dyadic International's E10 compare to GRDX and TVGN?
Dyadic International's E10 of $-0.30 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Dyadic International and its competitors. Dyadic International's current E10 is $-0.30. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Dyadic International stock overvalued right now?
Based on GuruFocus' analysis, Dyadic International (DYAI) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.74, compared to a current price of $1.47 — trading 98.6% above its estimated fair value. The current E10 is $-0.30. Dyadic International's overall GF Score™ is 37/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Dyadic International (DYAI), the current E10 is $-0.30 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Dyadic International (DYAI) Overvalued in 2026?

Based on GuruFocus' analysis, Dyadic International stock appears to be overvalued. The current stock price of $1.47 is trading 98.6% above its estimated GF Value™ of $0.74. GuruFocus considers Dyadic International to be Significantly Overvalued.

Key valuation signals for DYAI:

  • E10: $-0.30
  • GF Value™: $0.74 vs. price of $1.47 (98.6% above fair value)
  • GF Score™: 37/100 with 7 warning signs

No single metric tells the full story. See the DYAI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Dyadic International Business Description

Address 1044 North U.S. Highway One, Suite 201, Jupiter, FL, USA, 33477
Dyadic International Inc is a biotechnology platform company. It has developed a gene expression platform for producing commercial quantities of industrial enzymes and other proteins and has licensed this technology to third parties, such as Abengoa Bioenergy, BASF, Codexis and others, for use in industrial (non-pharmaceutical) applications. This technology is based on the Thermothelomyces heterothallica fungus, which the company named C1.
37GF Score

Get the complete analysis for DYAI

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.47
Price
$0.74
GF Value