DYAI (Dyadic International) Net Margin %: -313.30% (As of Mar. 2026)

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DYAI Dyadic International Inc DYAI
37 GF Score
Price $1.48
GF Value $0.74
Valuation Significantly Overvalued
! 7 Warning Signs
View Full Analysis

What is Dyadic International Net Margin %?

Dyadic International DYAI +22.31% 37 Net Margin % is -313.30% as of Mar. 2026. GuruFocus rates DYAI with a GF Score™ of 37/100 and a GF Value™ of $0.74 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 942 Biotechnology companies, Dyadic International ranks worse than 69.64% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Dyadic International's Net Income for the three months ended in Mar. 2026 was $-1.96 Mil. Dyadic International's Revenue for the three months ended in Mar. 2026 was $0.62 Mil. Therefore, Dyadic International's net margin for the quarter that ended in Mar. 2026 was -313.30%.

The historical rank and industry rank for Dyadic International's Net Margin % or its related term are showing as below:

DYAI' s Net Margin % Range Over the Past 10 Years
Min: -608.6   Med: -466.89   Max: -166.21
Current: -435.86


DYAI's Net Margin % is ranked worse than
69.64% of 942 companies
in the Biotechnology industry
Industry Median: -88.295 vs DYAI: -435.86

Dyadic International  (NAS:DYAI) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Dyadic International Net Margin % Related Terms


Dyadic International Net Margin % Historical Data

* Premium members only.

The historical data trend for Dyadic International's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Dyadic International Net Margin % Chart

Dyadic International Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -543.68 -332.25 -234.39 -166.21 -597.81

Dyadic International Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1,108.20 -387.47 -564.57 -663.98 -313.30

DYAI vs GRDX, TVGN, KYNB: Net Margin % Comparison

For the Biotechnology subindustry, Dyadic International's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Dyadic International Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Dyadic International's Net Margin % distribution charts can be found below:

* The bar in red indicates where Dyadic International's Net Margin % falls into.


DYAI
37GF Score
Dyadic International Inc DYAI
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Dyadic International Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Dyadic International's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-7.365/1.232
=-597.81 %

Dyadic International's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin=Net Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-1.955/0.624
=-313.30 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -313.30% mean?
Dyadic International (DYAI) has a Net Margin % of -313.30% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Dyadic International and its competitors. According to the industry distribution chart, Dyadic International ranks #656 out of 942 companies in the Biotechnology industry, placing it in the top 69.6%.
Is Dyadic International's Net Margin % too high?
Dyadic International's current Net Margin % is -313.30%. Based on the distribution chart, Dyadic International ranks #656 out of 942 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Dyadic International has a GF Score™ of 37/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Dyadic International's Net Margin % compare to GRDX and TVGN?
According to the Biotechnology industry distribution chart, Dyadic International ranks #656 out of 942 companies for Net Margin %. This places Dyadic International in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Dyadic International and its competitors. Dyadic International's current Net Margin % is -313.30%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Dyadic International stock overvalued right now?
Based on GuruFocus' analysis, Dyadic International (DYAI) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.74, compared to a current price of $1.48 — trading 100% above its estimated fair value. The current Net Margin % is -313.30%. Dyadic International's overall GF Score™ is 37/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Dyadic International (DYAI), the current Net Margin % is -313.30% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Dyadic International (DYAI) Overvalued in 2026?

Based on GuruFocus' analysis, Dyadic International stock appears to be overvalued. The current stock price of $1.48 is trading 100% above its estimated GF Value™ of $0.74. GuruFocus considers Dyadic International to be Significantly Overvalued.

Key valuation signals for DYAI:

  • Net Margin %: -313.30%
  • GF Value™: $0.74 vs. price of $1.48 (100% above fair value)
  • GF Score™: 37/100 with 7 warning signs

No single metric tells the full story. See the DYAI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Dyadic International Business Description

Address 1044 North U.S. Highway One, Suite 201, Jupiter, FL, USA, 33477
Dyadic International Inc is a biotechnology platform company. It has developed a gene expression platform for producing commercial quantities of industrial enzymes and other proteins and has licensed this technology to third parties, such as Abengoa Bioenergy, BASF, Codexis and others, for use in industrial (non-pharmaceutical) applications. This technology is based on the Thermothelomyces heterothallica fungus, which the company named C1.
37GF Score

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Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.48
Price
$0.74
GF Value