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Dyadic InternationalDYAI +23.06%37 PS Ratio is 29.20 as of Jul. 21, 2026, which is 35% below its 10-year median of 44.94. GuruFocus rates DYAI with a GF Score™ of 37/100 and a GF Value™ of $0.74 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 930 Biotechnology companies, Dyadic International ranks worse than 70.11% on this metric.
The PS Ratio, or Price-to-Sales ratio, or Price/Sales, is a financial ratio used to compare a company's market price to its Revenue per Share. As of today, Dyadic International's share price is $1.489.
Dyadic International's Revenue per Share for the trailing twelve months (TTM) ended in Mar. 2026 was $0.05. Hence, Dyadic International's PS Ratio for today is 29.20.
Warning Sign:
Dyadic International Inc stock PS Ratio (=23.73) is close to 2-year high of 24.71.
The historical rank and industry rank for Dyadic International's PS Ratio or its related term are showing as below:
DYAI'
s PS Ratio Range Over the Past 10 Years
Min: 6.51 Med: 44.94 Max: 553.33
Current: 29.21
During the past 13 years, Dyadic International's highest PS Ratio was 553.33. The lowest was 6.51. And the median was 44.94.
DYAI's PS Ratio is ranked worse than 70.11% of 930
companies
in the Biotechnology industry
Industry Median: 9.3
vs DYAI: 29.21
Dyadic International Inc revenue per share has been in decline for the last 5 years.
During the past 12 months, the average Revenue per Share Growth Rate of Dyadic International was -54.90% per year.
During the past 3 years, the average Revenue per Share Growth Rate was -28.30% per year.
During the past 5 years, the average Revenue per Share Growth Rate was -3.30% per year.
During the past 10 years, the average Revenue per Share Growth Rate was 21.30% per year.
During the past 13 years, Dyadic International's highest 3-Year average Revenue per Share Growth Rate was 146.60% per year. The lowest was -83.90% per year. And the median was 19.35% per year.
Back to Basics: PS Ratio
Dyadic International (NAS:DYAI) PS Ratio Explanation
The PS Ratio is an excellent valuation indicator if you want to compare a stock with its historical valuation or with the stocks in the same industry. The PS Ratio works especially well when you want to compare the stock's current valuation with its historical valuation. The PS Ratio is a great valuation tool for evaluating cyclical businesses where the PE Ratio works poorly. It works the best when comparing the current valuation with the historical valuation because over time, a company's profit margin tends to revert to the mean.
When the PS Ratio is applied to the whole stock market, it can be used to evaluate the current market valuation and projected returns. In this case, the price is the total market cap of all stocks that are traded, and sales are the GDP of the country. This is how Warren Buffett estimates the broad market valuation and project future returns.
The PS Ratio does not tell you how cheap or expensive the stock is. It cannot be used to compare companies in different industries. It works better for companies within the same industry because these companies tend to have similar capital structures and profit margins. It works the best when comparing a company with itself in the past.
Dyadic International PS Ratio Related Terms
Dyadic International PS Ratio Historical Data
* Premium members only.
The historical data trend for Dyadic International's PS Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Dyadic International's PS Ratio, along with its competitors' market caps and PS Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Dyadic International PS Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Dyadic International's PS Ratio distribution charts can be found below:
* The bar in red indicates where Dyadic International's PS Ratio falls into.
The PS Ratio, or Price-to-Sales ratio, or Price/Sales, is a financial ratio used to compare a company's market price to its Revenue per Share. It is a ratio widely used to value stocks and it was first used by Ken Fisher.
Dyadic International's Share Price of today is $1.489. Dyadic International's Revenue per Share for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $0.05.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
Dyadic International (DYAI) has a PS Ratio of 29.20 as of Jul. 21, 2026. Price-to-Sales ratio is the ratio of share price to a company's revenue per share. View historical data on Dyadic International and its competitors. This is 35% below median its historical median of 44.94. Over the past decade, Dyadic International's PS Ratio has ranged from 6.51 to 553.33. According to the industry distribution chart, Dyadic International ranks #652 out of 930 companies in the Biotechnology industry, placing it in the top 70.1%.
Is Dyadic International's PS Ratio too high?
Dyadic International's current PS Ratio of 29.20 is 35% below median its 10-year median of 44.94. Over the past 10 years, this metric has ranged from a low of 6.51 to a high of 553.33. The Biotechnology industry median PS Ratio is 9.30. Dyadic International's value of 29.20 is 214% above this industry median. Based on the distribution chart, Dyadic International ranks #652 out of 930 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Dyadic International has a GF Score™ of 37/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Dyadic International's PS Ratio compare to GRDX and TVGN?
According to the Biotechnology industry distribution chart, Dyadic International ranks #652 out of 930 companies for PS Ratio. This places Dyadic International in the lower half of its industry. The industry median PS Ratio is 9.30. Dyadic International's value of 29.20 is 214% above this benchmark. Historically, Dyadic International's own PS Ratio has ranged from 6.51 to 553.33 over the past decade. While the company's 10-year median is 44.94 vs. the industry median of 9.30, Dyadic International has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PS Ratio for a Biotechnology company?
The median PS Ratio among Biotechnology companies is 9.30, based on 930 companies in the industry. Companies in the top quartile (top 25%) have a PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Dyadic International's current PS Ratio of 29.20 is 214% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PS Ratio mean?
A high PS Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Sales ratio is the ratio of share price to a company's revenue per share. View historical data on Dyadic International and its competitors. For the Biotechnology industry, the median PS Ratio is 9.30 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Dyadic International's current PS Ratio is 29.20, which is 35% below median its own 10-year median of 44.94. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Dyadic International stock overvalued right now?
Based on GuruFocus' analysis, Dyadic International (DYAI) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.74, compared to a current price of $1.49 — trading 101.2% above its estimated fair value. The current PS Ratio is 29.20, which is 35% below median its 10-year median of 44.94 and 214% above the Biotechnology industry median of 9.30. Dyadic International's overall GF Score™ is 37/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PS Ratio calculated?
PS Ratio is calculated from a company's financial statements. For Dyadic International (DYAI), the current PS Ratio is 29.20 as of Jul. 21, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Dyadic International (DYAI) Overvalued in 2026?
Based on GuruFocus' analysis, Dyadic International stock appears to be overvalued.
The current stock price of $1.49 is trading 101.2% above its estimated GF Value™ of $0.74.
GuruFocus considers Dyadic International to be Significantly Overvalued.
Key valuation signals for DYAI:
PS Ratio: 29.20 (35% below median its 10-year median of 44.94)
GF Value™: $0.74 vs. price of $1.49 (101.2% above fair value)
Industry Position: 214% above the Biotechnology median (#652 of 930)
No single metric tells the full story. See the DYAI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Dyadic International Inc is a biotechnology platform company. It has developed a gene expression platform for producing commercial quantities of industrial enzymes and other proteins and has licensed this technology to third parties, such as Abengoa Bioenergy, BASF, Codexis and others, for use in industrial (non-pharmaceutical) applications. This technology is based on the Thermothelomyces heterothallica fungus, which the company named C1.
37GF Score
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