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The historical rank and industry rank for Dyadic International's Gross Margin % or its related term are showing as below:
DYAI'
s Gross Margin % Range Over the Past 10 Years
Min: -88.31 Med: 16.12 Max: 65.84
Current: -68.2
During the past 13 years, the highestGross Margin % of Dyadic International was 65.84%. The lowest was -88.31%. And the median was 16.12%.
DYAI's Gross Margin % is ranked worse than 95.77% of 733
companies
in the Biotechnology industry
Industry Median: 60.91
vs DYAI: -68.20
Dyadic International had a gross margin of -26.92% for the quarter that ended in Mar. 2026 => No sustainable competitive advantage
The 5-Year average Growth Rate of Gross Margin for Dyadic International was 0.00% per year.
Dyadic International (NAS:DYAI) Gross Margin % Explanation
Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.
Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %
1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key
Dyadic International had a gross margin of -26.92% for the quarter that ended in Mar. 2026 => No sustainable competitive advantage
Be Aware
If a company loses its competitive advantages, usually its gross margin declines well before its sales declines. Watching Gross Margin % and Operating Margin % closely helps avoid value trap situations.
Dyadic International Gross Margin % Related Terms
Dyadic International Gross Margin % Historical Data
* Premium members only.
The historical data trend for Dyadic International's Gross Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
DYAI vs GRDX, TVGN, KYNB: Gross Margin % Comparison
For the Biotechnology subindustry, Dyadic International's Gross Margin %, along with its competitors' market caps and Gross Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Dyadic International Gross Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Dyadic International's Gross Margin % distribution charts can be found below:
* The bar in red indicates where Dyadic International's Gross Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.
Dyadic International (DYAI) has a Gross Margin % of -26.92% as of Mar. 2026. Gross margin is the ratio of total gross profit to net sales. View historical data on Dyadic International and its competitors. According to the industry distribution chart, Dyadic International ranks #702 out of 733 companies in the Biotechnology industry, placing it in the top 95.8%.
Is Dyadic International's Gross Margin % too high?
Dyadic International's current Gross Margin % is -26.92%. Based on the distribution chart, Dyadic International ranks #702 out of 733 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Dyadic International has a GF Score™ of 37/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Dyadic International's Gross Margin % compare to GRDX and TVGN?
According to the Biotechnology industry distribution chart, Dyadic International ranks #702 out of 733 companies for Gross Margin %. This places Dyadic International in the lower half of its industry. The industry median Gross Margin % is 60.91. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Gross Margin % for a Biotechnology company?
The median Gross Margin % among Biotechnology companies is 60.91, based on 733 companies in the industry. Companies in the top quartile (top 25%) have a Gross Margin % significantly above this median, while those in the bottom quartile fall well below. However, Gross Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Gross Margin % mean?
A high Gross Margin % can signal that a stock is expensive relative to its fundamentals. Gross margin is the ratio of total gross profit to net sales. View historical data on Dyadic International and its competitors. For the Biotechnology industry, the median Gross Margin % is 60.91 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Dyadic International's current Gross Margin % is -26.92%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Dyadic International stock overvalued right now?
Based on GuruFocus' analysis, Dyadic International (DYAI) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.74, compared to a current price of $1.50 — trading 102.7% above its estimated fair value. The current Gross Margin % is -26.92%. Dyadic International's overall GF Score™ is 37/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Gross Margin % calculated?
Gross Margin % is calculated from a company's financial statements. For Dyadic International (DYAI), the current Gross Margin % is -26.92% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Dyadic International (DYAI) Overvalued in 2026?
Based on GuruFocus' analysis, Dyadic International stock appears to be overvalued.
The current stock price of $1.50 is trading 102.7% above its estimated GF Value™ of $0.74.
GuruFocus considers Dyadic International to be Significantly Overvalued.
Key valuation signals for DYAI:
Gross Margin %: -26.92%
GF Value™: $0.74 vs. price of $1.50 (102.7% above fair value)
No single metric tells the full story. See the DYAI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Dyadic International Inc is a biotechnology platform company. It has developed a gene expression platform for producing commercial quantities of industrial enzymes and other proteins and has licensed this technology to third parties, such as Abengoa Bioenergy, BASF, Codexis and others, for use in industrial (non-pharmaceutical) applications. This technology is based on the Thermothelomyces heterothallica fungus, which the company named C1.
37GF Score
Get the complete analysis for DYAI
Gross Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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