Kyowa Kirin Co (TSE:4151) E10: 円113.47 (As of Dec. 2025)

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TSE:4151 Kyowa Kirin Co Ltd TSE:4151
90 GF Score
Price 円2,554.50
GF Value 円2,986.42
Valuation Modestly Undervalued
! 1 Warning Sign
View Full Analysis

What is Kyowa Kirin Co E10?

Kyowa Kirin Co TSE:4151 -3.60% 90 E10 is 円113.47 as of Dec. 2025. GuruFocus rates TSE:4151 with a GF Score™ of 90/100 and a GF Value™ of 円2,986.42 (Modestly Undervalued). The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Kyowa Kirin Co's adjusted earnings per share data for the three months ended in Dec. 2025 was 円65.790. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is 円113.47 for the trailing ten years ended in Dec. 2025.

During the past 12 months, Kyowa Kirin Co's average E10 Growth Rate was 8.40% per year. During the past 3 years, the average E10 Growth Rate was 11.50% per year. During the past 5 years, the average E10 Growth Rate was 11.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Kyowa Kirin Co was 12.40% per year. The lowest was 8.40% per year. And the median was 11.00% per year.

As of today (2026-07-31), Kyowa Kirin Co's current stock price is 円2554.50. Kyowa Kirin Co's E10 for the quarter that ended in Dec. 2025 was 円113.47. Kyowa Kirin Co's Shiller PE Ratio of today is 22.51.

During the past 13 years, the highest Shiller PE Ratio of Kyowa Kirin Co was 60.48. The lowest was 19.72. And the median was 37.17.


Kyowa Kirin Co  (TSE:4151) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Kyowa Kirin Co's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=2554.50/113.47
=22.51

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Kyowa Kirin Co was 60.48. The lowest was 19.72. And the median was 37.17.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Kyowa Kirin Co E10 Related Terms


Kyowa Kirin Co E10 Historical Data

* Premium members only.

The historical data trend for Kyowa Kirin Co's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Kyowa Kirin Co E10 Chart

Kyowa Kirin Co Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 73.61 81.86 93.01 104.66 113.47

Kyowa Kirin Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 105.26 106.75 106.72 113.47 0.00

TSE:4151 vs ZTS: E10 Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Kyowa Kirin Co's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Kyowa Kirin Co Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Kyowa Kirin Co's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Kyowa Kirin Co's Shiller PE Ratio falls into.


TSE:4151
90GF Score
Kyowa Kirin Co Ltd TSE:4151
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Kyowa Kirin Co E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Kyowa Kirin Co's adjusted earnings per share data for the three months ended in Dec. 2025 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=65.79/113.0000*113.0000
=65.790

Current CPI (Dec. 2025) = 113.0000.

Kyowa Kirin Co Quarterly Data

per share eps CPI Adj_EPS
201603 13.510 97.900 15.594
201606 6.140 98.100 7.073
201609 10.420 98.000 12.015
201612 25.520 98.400 29.307
201703 21.940 98.100 25.272
201706 15.200 98.500 17.438
201709 16.640 98.800 19.032
201712 24.520 99.400 27.875
201803 40.160 99.200 45.747
201806 22.380 99.200 25.493
201809 23.990 99.900 27.136
201812 12.770 99.700 14.474
201903 14.950 99.700 16.944
201906 74.340 99.800 84.173
201909 15.360 100.100 17.339
201912 20.070 100.500 22.566
202003 25.760 100.300 29.022
202006 25.970 99.900 29.375
202009 18.030 99.900 20.394
202012 17.750 99.300 20.199
202103 24.040 99.900 27.192
202106 22.610 99.500 25.678
202109 14.580 100.100 16.459
202112 36.170 100.100 40.831
202203 29.840 101.100 33.352
202206 35.300 101.800 39.184
202209 26.410 103.100 28.946
202212 8.110 104.100 8.803
202303 23.740 104.400 25.696
202306 16.530 105.200 17.756
202309 59.350 106.200 63.150
202312 51.400 106.800 54.384
202403 27.260 107.200 28.735
202406 43.550 108.200 45.482
202409 34.440 108.900 35.737
202412 7.870 110.700 8.034
202503 11.780 111.100 11.981
202506 19.400 111.700 19.626
202509 31.100 112.000 31.378
202512 65.790 113.000 65.790

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of 円113.47 mean?
Kyowa Kirin Co (TSE:4151) has a E10 of 円113.47 as of Dec. 2025. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Kyowa Kirin Co and its competitors.
Is Kyowa Kirin Co's E10 too high?
Kyowa Kirin Co's current E10 is 円113.47. Overall, Kyowa Kirin Co has a GF Score™ of 90/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Kyowa Kirin Co's E10 compare to ZTS?
Kyowa Kirin Co's E10 of 円113.47 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Kyowa Kirin Co and its competitors. Kyowa Kirin Co's current E10 is 円113.47. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Kyowa Kirin Co stock overvalued right now?
Based on GuruFocus' analysis, Kyowa Kirin Co (TSE:4151) is currently considered Modestly Undervalued. The stock's GF Value™ is 円2,986.42, compared to a current price of 円2,554.50 — trading 14.5% below its estimated fair value. The current E10 is 円113.47. Kyowa Kirin Co's overall GF Score™ is 90/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Kyowa Kirin Co (TSE:4151), the current E10 is 円113.47 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Kyowa Kirin Co (TSE:4151) Overvalued in 2026?

Based on GuruFocus' analysis, Kyowa Kirin Co stock appears to be undervalued. The current stock price of 円2,554.50 is trading 14.5% below its estimated GF Value™ of 円2,986.42. GuruFocus considers Kyowa Kirin Co to be Modestly Undervalued.

Key valuation signals for TSE:4151:

  • E10: 円113.47
  • GF Value™: 円2,986.42 vs. price of 円2,554.50 (14.5% below fair value)
  • GF Score™: 90/100 with 1 warning sign

No single metric tells the full story. See the TSE:4151 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Kyowa Kirin Co Business Description

Address 1-9-2 Otemachi, Chiyoda-ku, Chiyoda-ku, Tokyo, JPN, 100-0004
Kyowa Kirin Co Ltd is engaged in research, development, manufacturing, sales, import and export of prescription pharmaceuticals. Its products include KHK4083/AMG 451, rocatinlimab; ziftomenib; OTL-203 KK8398, infigratinib; KHK4951, tivozanib; OTL-201; KK4277; KK2260; KK2269; KK2845; and KK8123.
90GF Score

Get the complete analysis for TSE:4151

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円2,554.50
Price
円2,986.42
GF Value