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Silence TherapeuticsSLN +1.96%46 Earnings per Share (Diluted) is $-1.62 as of Mar. 2026. GuruFocus rates SLN with a GF Score™ of 46/100 and a GF Value™ of $0.13 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 1,161 Biotechnology companies, Silence Therapeutics ranks worse than 74.07% on this metric.
Silence Therapeutics's EPS (Basic) for the
three
months ended in Mar. 2026 was $-0.33.
Its EPS (Basic) for the trailing twelve months (TTM) ended in Mar. 2026 was $-1.62.
During the past 3 years, the average EPS without NRIGrowth Rate was -2.90% per year.
During the past 5 years, the average EPS without NRIGrowth Rate was 4.20% per year.
During the past 10 years, the average EPS without NRIGrowth Rate was -13.50% per year.
During the past 13 years, Silence Therapeutics's highest 3-Year average EPS without NRI Growth Rate was 53.50% per year. The lowest was -39.80% per year. And the median was 4.00% per year.
Silence Therapeutics (NAS:SLN) Earnings per Share (Diluted) Explanation
Earnings Per Share (EPS) is the single most important variable used by Wall Street in determining the earnings power of a company. But investors need to be aware that Earnings per Share can be easily manipulated by adjusting depreciation and amortization rate or non-recurring items. That's why GuruFocus lists EPS without NRI, which better reflects the company's underlying performance.
Be Aware
Compared with Earnings per share, a company's cash flow is better indicator of the company's earnings power.
If a company's earnings per share is less than cash flow per share over long term, investors need to be cautious and find out why.
Silence Therapeutics Earnings per Share (Diluted) Related Terms
Silence Therapeutics Earnings per Share (Diluted) Historical Data
* Premium members only.
The historical data trend for Silence Therapeutics's Earnings per Share (Diluted) can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Silence Therapeutics Earnings per Share (Diluted) Chart
SLN vs NAUT, CHRS, NBP: Earnings per Share (Diluted) Comparison
For the Biotechnology subindustry, Silence Therapeutics's PE Ratio, along with its competitors' market caps and PE Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Silence Therapeutics PE Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Silence Therapeutics's PE Ratio distribution charts can be found below:
* The bar in red indicates where Silence Therapeutics's PE Ratio falls into.
Silence Therapeutics Earnings per Share (Diluted) Calculation
Earnings Per Share (EPS) is the amount of earnings per outstanding share of the company's stock. In calculating earnings per share, the dividends of preferred stocks need to subtracted from the total net income first.
Silence Therapeutics's Earnings Per Share (Diluted) for the fiscal year that ended in Dec. 2025 is calculated as
Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.62
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Companies also reported diluted shares in their financial reports. Diluted shares include the shares of convertibles or warrants outstanding.
What does a Earnings per Share (Diluted) of $-1.62 mean?
Silence Therapeutics (SLN) has a Earnings per Share (Diluted) of $-1.62 as of Mar. 2026. Diluted EPS equals net earnings divided by average shares outstanding, including dilutive securities. View historical data on Silence Therapeutics and its competitors. According to the industry distribution chart, Silence Therapeutics ranks #860 out of 1161 companies in the Biotechnology industry, placing it in the top 74.1%.
Is Silence Therapeutics' Earnings per Share (Diluted) too high?
Silence Therapeutics' current Earnings per Share (Diluted) is $-1.62. Based on the distribution chart, Silence Therapeutics ranks #860 out of 1161 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Silence Therapeutics has a GF Score™ of 46/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Silence Therapeutics' Earnings per Share (Diluted) compare to NAUT and CHRS?
According to the Biotechnology industry distribution chart, Silence Therapeutics ranks #860 out of 1161 companies for Earnings per Share (Diluted). This places Silence Therapeutics in the lower half of its industry. The industry median Earnings per Share (Diluted) is 16.20. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Earnings per Share (Diluted) for a Biotechnology company?
The median Earnings per Share (Diluted) among Biotechnology companies is 16.20, based on 1,161 companies in the industry. Companies in the top quartile (top 25%) have a Earnings per Share (Diluted) significantly above this median, while those in the bottom quartile fall well below. However, Earnings per Share (Diluted) should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Earnings per Share (Diluted) mean?
A high Earnings per Share (Diluted) can signal that a stock is expensive relative to its fundamentals. Diluted EPS equals net earnings divided by average shares outstanding, including dilutive securities. View historical data on Silence Therapeutics and its competitors. For the Biotechnology industry, the median Earnings per Share (Diluted) is 16.20 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Silence Therapeutics's current Earnings per Share (Diluted) is $-1.62. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Silence Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Silence Therapeutics (SLN) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.13, compared to a current price of $11.94 — trading 9084.6% above its estimated fair value. The current Earnings per Share (Diluted) is $-1.62. Silence Therapeutics' overall GF Score™ is 46/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Earnings per Share (Diluted) calculated?
Earnings per Share (Diluted) is calculated from a company's financial statements. For Silence Therapeutics (SLN), the current Earnings per Share (Diluted) is $-1.62 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Silence Therapeutics (SLN) Overvalued in 2026?
Based on GuruFocus' analysis, Silence Therapeutics stock appears to be overvalued.
The current stock price of $11.94 is trading 9084.6% above its estimated GF Value™ of $0.13.
GuruFocus considers Silence Therapeutics to be Significantly Overvalued.
Key valuation signals for SLN:
Earnings per Share (Diluted): $-1.62
GF Value™: $0.13 vs. price of $11.94 (9084.6% above fair value)
No single metric tells the full story. See the SLN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Silence Therapeutics PLC is a biotechnology company focused on discovering and developing novel molecules incorporating short-interfering ribonucleic acid or siRNA. Using its mRNAi GOLD platform, the company has generated siRNA product candidates both for its internal development pipeline as well as for out-licensed programs with third-party collaborators. Its wholly owned pipeline is focused on three therapeutic areas: cardiovascular disease, hematology, and rare diseases. The different product candidates in its pipeline are Divesiran (SLN124), a siRNA product candidate that has the potential to treat several hematological disorders; Zerlasiran (SLN360), being developed as a potential treatment to reduce cardiovascular issues; SLN-312; SLN-548; and multiple other programs.
46GF Score
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Earnings per Share (Diluted) is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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