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Silence TherapeuticsSLN +0.26%45 Earnings Yield (Joel Greenblatt) % is -36.10% as of Mar. 2026. GuruFocus rates SLN with a GF Score™ of 45/100 and a GF Value™ of $0.39 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 1,319 Biotechnology companies, Silence Therapeutics ranks worse than 81.96% on this metric.
Silence Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $178.99 Mil.
Silence Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-77.08 Mil. Silence Therapeutics's Earnings Yield (Joel Greenblatt) for the quarter that ended in Mar. 2026 was -36.10%.
The historical rank and industry rank for Silence Therapeutics's Earnings Yield (Joel Greenblatt) % or its related term are showing as below:
SLN'
s Earnings Yield (Joel Greenblatt) % Range Over the Past 10 Years
Min: -9024.02 Med: -24.77 Max: 4584.79
Current: -54.05
During the past 13 years, the highest Earnings Yield (Joel Greenblatt) of Silence Therapeutics was 4584.79%. The lowest was -9024.02%. And the median was -24.77%.
SLN's Earnings Yield (Joel Greenblatt) % is ranked worse than 81.96% of 1319
companies
in the Biotechnology industry
Industry Median: -10.32
vs SLN: -54.05
Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.
A better indicator of the attractiveness of an investment which takes growth into account is the Forward Rate of Return (Yacktman) %. Silence Therapeutics's Forward Rate of Return (Yacktman) % for the quarter that ended in Mar. 2026 was 0.00%. The Forward Rate of Return uses the normalized Free Cash Flow of the past five years, and considers growth. The forward rate of return can be thought of as the return that investors buying the stock today can expect from it in the future.
Joel Greenblatt defines the earnings yield using the above equation because it more accurately reflects the company's profitability relative to its stock price. Items like interest payment and tax etc. are not directly related to the company's operational profitability.
Enterprise Value instead of market cap (share price) is used in the calculation because it is the real price stock and bond investors together pay for the company.
Be Aware
Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.
Silence Therapeutics Earnings Yield (Joel Greenblatt) % Related Terms
Silence Therapeutics Earnings Yield (Joel Greenblatt) % Historical Data
* Premium members only.
The historical data trend for Silence Therapeutics's Earnings Yield (Joel Greenblatt) % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Silence Therapeutics's Earnings Yield (Joel Greenblatt) %, along with its competitors' market caps and Earnings Yield (Joel Greenblatt) % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Silence Therapeutics Earnings Yield (Joel Greenblatt) % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Silence Therapeutics's Earnings Yield (Joel Greenblatt) % distribution charts can be found below:
* The bar in red indicates where Silence Therapeutics's Earnings Yield (Joel Greenblatt) % falls into.
In his book, The Little That Beat the Market, hedge fund manager Joel Greenblatt defines Earnings Yield as operating income divided by enterprise value.
Silence Therapeuticss Earnings Yield (Joel Greenblatt) for the fiscal year that ended in Dec. 2025 is calculated as
Silence Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-77.08 Mil.
What does a Earnings Yield (Joel Greenblatt) % of -36.10% mean?
Silence Therapeutics (SLN) has a Earnings Yield (Joel Greenblatt) % of -36.10% as of Mar. 2026. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Silence Therapeutics and its competitors. According to the industry distribution chart, Silence Therapeutics ranks #1081 out of 1319 companies in the Biotechnology industry, placing it in the top 82%.
Is Silence Therapeutics' Earnings Yield (Joel Greenblatt) % too high?
Silence Therapeutics' current Earnings Yield (Joel Greenblatt) % is -36.10%. Based on the distribution chart, Silence Therapeutics ranks #1081 out of 1319 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Silence Therapeutics has a GF Score™ of 45/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Silence Therapeutics' Earnings Yield (Joel Greenblatt) % compare to NAUT and CHRS?
According to the Biotechnology industry distribution chart, Silence Therapeutics ranks #1081 out of 1319 companies for Earnings Yield (Joel Greenblatt) %. This places Silence Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Earnings Yield (Joel Greenblatt) % for a Biotechnology company?
A good Earnings Yield (Joel Greenblatt) % depends on the Biotechnology industry context. However, Earnings Yield (Joel Greenblatt) % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Earnings Yield (Joel Greenblatt) % mean?
A high Earnings Yield (Joel Greenblatt) % can signal that a stock is expensive relative to its fundamentals. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Silence Therapeutics and its competitors. Silence Therapeutics's current Earnings Yield (Joel Greenblatt) % is -36.10%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Silence Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Silence Therapeutics (SLN) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.39, compared to a current price of $11.55 — trading 2861.5% above its estimated fair value. The current Earnings Yield (Joel Greenblatt) % is -36.10%. Silence Therapeutics' overall GF Score™ is 45/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Earnings Yield (Joel Greenblatt) % calculated?
Earnings Yield (Joel Greenblatt) % is calculated from a company's financial statements. For Silence Therapeutics (SLN), the current Earnings Yield (Joel Greenblatt) % is -36.10% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Silence Therapeutics (SLN) Overvalued in 2026?
Based on GuruFocus' analysis, Silence Therapeutics stock appears to be overvalued.
The current stock price of $11.55 is trading 2861.5% above its estimated GF Value™ of $0.39.
GuruFocus considers Silence Therapeutics to be Significantly Overvalued.
Key valuation signals for SLN:
Earnings Yield (Joel Greenblatt) %: -36.10%
GF Value™: $0.39 vs. price of $11.55 (2861.5% above fair value)
No single metric tells the full story. See the SLN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Silence Therapeutics PLC is a biotechnology company focused on discovering and developing novel molecules incorporating short-interfering ribonucleic acid or siRNA. Using its mRNAi GOLD platform, the company has generated siRNA product candidates both for its internal development pipeline as well as for out-licensed programs with third-party collaborators. Its wholly owned pipeline is focused on three therapeutic areas: cardiovascular disease, hematology, and rare diseases. The different product candidates in its pipeline are Divesiran (SLN124), a siRNA product candidate that has the potential to treat several hematological disorders; Zerlasiran (SLN360), being developed as a potential treatment to reduce cardiovascular issues; SLN-312; SLN-548; and multiple other programs.
45GF Score
Get the complete analysis for SLN
Earnings Yield (Joel Greenblatt) % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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