SLN (Silence Therapeutics) EV-to-EBIT: -1.85 (As of Jul. 22, 2026)

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SLN Silence Therapeutics PLC SLN
45 GF Score
Price $10.85
GF Value $0.36
Valuation Significantly Overvalued
! 5 Warning Signs
View Full Analysis

What is Silence Therapeutics EV-to-EBIT?

Silence Therapeutics SLN +3.43% 45 EV-to-EBIT is -1.85 as of Jul. 22, 2026. GuruFocus rates SLN with a GF Score™ of 45/100 and a GF Value™ of $0.36 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 372 Biotechnology companies, Silence Therapeutics ranks worse than 268816.94% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Silence Therapeutics's Enterprise Value is $142.61 Mil. Silence Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-77.08 Mil. Therefore, Silence Therapeutics's EV-to-EBIT for today is -1.85.

The historical rank and industry rank for Silence Therapeutics's EV-to-EBIT or its related term are showing as below:

SLN' s EV-to-EBIT Range Over the Past 10 Years
Min: -43.31   Med: -3.65   Max: 0.33
Current: -1.85

During the past 13 years, the highest EV-to-EBIT of Silence Therapeutics was 0.33. The lowest was -43.31. And the median was -3.65.

SLN's EV-to-EBIT is ranked worse than
100% of 372 companies
in the Biotechnology industry
Industry Median: 13.475 vs SLN: -1.85

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Silence Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $178.99 Mil. Silence Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-77.08 Mil. Silence Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -43.07%.


Silence Therapeutics  (NAS:SLN) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Silence Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Mar. 2026 ) =EBIT / Enterprise Value (Q: Mar. 2026 )
=-77.081/178.98645
=-43.07 %

Silence Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $178.99 Mil.
Silence Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-77.08 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Silence Therapeutics EV-to-EBIT Related Terms


Silence Therapeutics EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Silence Therapeutics's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Silence Therapeutics EV-to-EBIT Chart

Silence Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial Premium Member Only Premium Member Only -8.77 -4.34 -1.71 -3.55 -2.21

Silence Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.27 -1.32 -1.27 -2.21 -2.77

SLN vs IMRX, VRXA, MGNX: EV-to-EBIT Comparison

For the Biotechnology subindustry, Silence Therapeutics's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Silence Therapeutics EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Silence Therapeutics's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Silence Therapeutics's EV-to-EBIT falls into.


SLN
45GF Score
Silence Therapeutics PLC SLN
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Silence Therapeutics EV-to-EBIT Calculation

Silence Therapeutics's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=142.614/-77.081
=-1.85

Silence Therapeutics's current Enterprise Value is $142.61 Mil.
Silence Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-77.08 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of -1.85 mean?
Silence Therapeutics (SLN) has a EV-to-EBIT of -1.85 as of Jul. 22, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Silence Therapeutics and its competitors. According to the industry distribution chart, Silence Therapeutics ranks #999999 out of 372 companies in the Biotechnology industry.
Is Silence Therapeutics' EV-to-EBIT too high?
Silence Therapeutics' current EV-to-EBIT is -1.85. Based on the distribution chart, Silence Therapeutics ranks #999999 out of 372 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Silence Therapeutics has a GF Score™ of 45/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Silence Therapeutics' EV-to-EBIT compare to IMRX and VRXA?
According to the Biotechnology industry distribution chart, Silence Therapeutics ranks #999999 out of 372 companies for EV-to-EBIT. This places Silence Therapeutics in the lower half of its industry. The industry median EV-to-EBIT is 13.48. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 13.48, based on 372 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Silence Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 13.48 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Silence Therapeutics's current EV-to-EBIT is -1.85. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Silence Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Silence Therapeutics (SLN) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.36, compared to a current price of $10.85 — trading 2913.9% above its estimated fair value. The current EV-to-EBIT is -1.85. Silence Therapeutics' overall GF Score™ is 45/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Silence Therapeutics (SLN), the current EV-to-EBIT is -1.85 as of Jul. 22, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Silence Therapeutics (SLN) Overvalued in 2026?

Based on GuruFocus' analysis, Silence Therapeutics stock appears to be overvalued. The current stock price of $10.85 is trading 2913.9% above its estimated GF Value™ of $0.36. GuruFocus considers Silence Therapeutics to be Significantly Overvalued.

Key valuation signals for SLN:

  • EV-to-EBIT: -1.85
  • GF Value™: $0.36 vs. price of $10.85 (2913.9% above fair value)
  • GF Score™: 45/100 with 5 warning signs

No single metric tells the full story. See the SLN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Silence Therapeutics Business Description

Other Exchanges SLNCF:USAXRP2:Germany
Address 12 Hammersmith Grove, London, GBR, W6 7AP
Silence Therapeutics PLC is a biotechnology company focused on discovering and developing novel molecules incorporating short-interfering ribonucleic acid or siRNA. Using its mRNAi GOLD platform, the company has generated siRNA product candidates both for its internal development pipeline as well as for out-licensed programs with third-party collaborators. Its wholly owned pipeline is focused on three therapeutic areas: cardiovascular disease, hematology, and rare diseases. The different product candidates in its pipeline are Divesiran (SLN124), a siRNA product candidate that has the potential to treat several hematological disorders; Zerlasiran (SLN360), being developed as a potential treatment to reduce cardiovascular issues; SLN-312; SLN-548; and multiple other programs.
45GF Score

Get the complete analysis for SLN

EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$10.85
Price
$0.36
GF Value