TYRA (Tyra Biosciences) Earnings Yield (Joel Greenblatt) %: -7.52% (As of Mar. 2026)

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TYRA Tyra Biosciences Inc TYRA
28 GF Score
Price $30.70
! 2 Warning Signs
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What is Tyra Biosciences Earnings Yield (Joel Greenblatt) %?

Tyra Biosciences TYRA -0.39% 28 Earnings Yield (Joel Greenblatt) % is -7.52% as of Mar. 2026. GuruFocus rates TYRA with a GF Score™ of 28/100. The stock has 2 warning signs investors should review. Among 1,324 Biotechnology companies, Tyra Biosciences ranks better than 50.6% on this metric.

Tyra Biosciences's Enterprise Value for the quarter that ended in Mar. 2026 was $1,899.94 Mil. Tyra Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-142.91 Mil. Tyra Biosciences's Earnings Yield (Joel Greenblatt) for the quarter that ended in Mar. 2026 was -7.52%.

The historical rank and industry rank for Tyra Biosciences's Earnings Yield (Joel Greenblatt) % or its related term are showing as below:

TYRA' s Earnings Yield (Joel Greenblatt) % Range Over the Past 10 Years
Min: -9.87   Med: 0   Max: 0
Current: -9.87

TYRA's Earnings Yield (Joel Greenblatt) % is ranked better than
50.6% of 1324 companies
in the Biotechnology industry
Industry Median: -10.17 vs TYRA: -9.87

Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.

A better indicator of the attractiveness of an investment which takes growth into account is the Forward Rate of Return (Yacktman) %. Tyra Biosciences's Forward Rate of Return (Yacktman) % for the quarter that ended in Mar. 2026 was 0.00%. The Forward Rate of Return uses the normalized Free Cash Flow of the past five years, and considers growth. The forward rate of return can be thought of as the return that investors buying the stock today can expect from it in the future.


Tyra Biosciences  (NAS:TYRA) Earnings Yield (Joel Greenblatt) % Explanation

Joel Greenblatt defines the earnings yield using the above equation because it more accurately reflects the company's profitability relative to its stock price. Items like interest payment and tax etc. are not directly related to the company's operational profitability.

Enterprise Value instead of market cap (share price) is used in the calculation because it is the real price stock and bond investors together pay for the company.


Be Aware

Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.

Forward Rate of Return (Yacktman) % based on Don Yacktman's definition is a better measure of the expected rate of return for a stock.


Tyra Biosciences Earnings Yield (Joel Greenblatt) % Related Terms


Tyra Biosciences Earnings Yield (Joel Greenblatt) % Historical Data

* Premium members only.

The historical data trend for Tyra Biosciences's Earnings Yield (Joel Greenblatt) % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tyra Biosciences Earnings Yield (Joel Greenblatt) % Chart

Tyra Biosciences Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Earnings Yield (Joel Greenblatt) %
Get a 7-Day Free Trial -9.32 -80.65 -20.04 -28.17 -11.43

Tyra Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Earnings Yield (Joel Greenblatt) % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -62.89 -55.56 -26.39 -11.43 -7.52

TYRA vs SION, IOVA, SNDX: Earnings Yield (Joel Greenblatt) % Comparison

For the Biotechnology subindustry, Tyra Biosciences's Earnings Yield (Joel Greenblatt) %, along with its competitors' market caps and Earnings Yield (Joel Greenblatt) % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Tyra Biosciences Earnings Yield (Joel Greenblatt) % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Tyra Biosciences's Earnings Yield (Joel Greenblatt) % distribution charts can be found below:

* The bar in red indicates where Tyra Biosciences's Earnings Yield (Joel Greenblatt) % falls into.


TYRA
28GF Score
Tyra Biosciences Inc TYRA
Earnings Yield (Joel Greenblatt) % is just one metric. See GF Score™, valuation, warning signs, and more.
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Tyra Biosciences Earnings Yield (Joel Greenblatt) % Calculation

In his book, The Little That Beat the Market, hedge fund manager Joel Greenblatt defines Earnings Yield as operating income divided by enterprise value.

Tyra Biosciencess Earnings Yield (Joel Greenblatt) for the fiscal year that ended in Dec. 2025 is calculated as

Earnings Yield (Joel Greenblatt)=EBIT/Enterprise Value
=-132.762/1161.74274
=-11.43 %

Tyra Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-142.91 Mil.


What does a Earnings Yield (Joel Greenblatt) % of -7.52% mean?
Tyra Biosciences (TYRA) has a Earnings Yield (Joel Greenblatt) % of -7.52% as of Mar. 2026. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Tyra Biosciences and its competitors. According to the industry distribution chart, Tyra Biosciences ranks #654 out of 1324 companies in the Biotechnology industry, placing it in the top 49.4%.
Is Tyra Biosciences' Earnings Yield (Joel Greenblatt) % too high?
Tyra Biosciences' current Earnings Yield (Joel Greenblatt) % is -7.52%. Based on the distribution chart, Tyra Biosciences ranks #654 out of 1324 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Tyra Biosciences has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Tyra Biosciences' Earnings Yield (Joel Greenblatt) % compare to SION and IOVA?
According to the Biotechnology industry distribution chart, Tyra Biosciences ranks #654 out of 1324 companies for Earnings Yield (Joel Greenblatt) %. This puts Tyra Biosciences in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Earnings Yield (Joel Greenblatt) % for a Biotechnology company?
A good Earnings Yield (Joel Greenblatt) % depends on the Biotechnology industry context. However, Earnings Yield (Joel Greenblatt) % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Earnings Yield (Joel Greenblatt) % mean?
A high Earnings Yield (Joel Greenblatt) % can signal that a stock is expensive relative to its fundamentals. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Tyra Biosciences and its competitors. Tyra Biosciences's current Earnings Yield (Joel Greenblatt) % is -7.52%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tyra Biosciences stock overvalued right now?
Tyra Biosciences (TYRA) has a current Earnings Yield (Joel Greenblatt) % of -7.52%. The current Earnings Yield (Joel Greenblatt) % is -7.52%. Tyra Biosciences' overall GF Score™ is 28/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Earnings Yield (Joel Greenblatt) % calculated?
Earnings Yield (Joel Greenblatt) % is calculated from a company's financial statements. For Tyra Biosciences (TYRA), the current Earnings Yield (Joel Greenblatt) % is -7.52% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Tyra Biosciences Business Description

Address 2656 State Street, Carlsbad, CA, USA, 92008
Tyra Biosciences Inc is a clinical-stage biotechnology company focused on developing next-generation precision medicines for large opportunities in targeted oncology and genetically defined conditions, harnessing the power of Fibroblast Growth Factor Receptor (FGFR) biology. The company's in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help to design and predict which product candidates may demonstrate the highest potency, selectivity, and tolerability in the clinic. The various drug candidates in the company's product pipeline are FGFR3, FGFR4/3, and FGFR1/2/3: three clinical-stage, novel small molecules designed to overcome the toxicity and resistance liabilities of first-generation pan-FGFR inhibitors.
28GF Score

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Earnings Yield (Joel Greenblatt) % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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