TYRA (Tyra Biosciences) Free Cash Flow: $-109.90 Mil (TTM As of Jun. 2026)

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TYRA Tyra Biosciences Inc TYRA
33 GF Score
Price $22.01
! 2 Warning Signs
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What is Tyra Biosciences Free Cash Flow?

Tyra Biosciences TYRA -17.66% 33 Free Cash Flow is $-109.90 Mil as of Jun. 2026. GuruFocus rates TYRA with a GF Score™ of 33/100. The stock has 2 warning signs investors should review.

Tyra Biosciences's total free cash flow for the months ended in Jun. 2026 was $-31.14 Mil. Its total free cash flow for the trailing twelve months (TTM) ended in Jun. 2026 was $-109.90 Mil.

Tyra Biosciences's Free Cash Flow per Share for the months ended in Jun. 2026 was $-0.47. Its free cash flow per share for the trailing twelve months (TTM) ended in Jun. 2026 was $-1.77.

During the past 3 years, the average Free Cash Flow per Share Growth Rate was -9.60% per year. During the past 5 years, the average Free Cash Flow per Share Growth Rate was -19.90% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Free Cash Flow Growth Rate using Free Cash Flow per Share data.

During the past 7 years, Tyra Biosciences's highest 3-Year average Free Cash Flow per Share Growth Rate was 11.40% per year. The lowest was -67.40% per year. And the median was -29.40% per year.


Tyra Biosciences  (NAS:TYRA) Free Cash Flow Explanation

Free Cash Flow is very close to Warren Buffett's definition of Owner's Earnings, except that in Warren Buffett's Owner's Earnings, the spending for Property, Plant, and Equipment is only for maintenance (replacement), while in the Free Cash Flow calculation, the cost of new Property, Plant, and Equipment due to business expansion is also deducted. There, Free Cash Flow is more conservative than Owner's Earnings.

In Don Yacktman's calculation of forward rate of return, he uses Free Cash Flow for the calculation. Yacktman explained the forward rate of return concept in detail in his interview with GuruFocus. Yacktman defines forward rate of return as the normalized free cash flow yield plus real growth plus inflation.

This is what Yacktman said in his March 2012 interview - when the S&P 500 was at 1400:

If the business is stable, this calculation is fairly straightforward. For instance, on the S&P 500 we would normalize earnings. We would then calculate what percentage of those earnings are not reinvested in the underlying businesses and are therefore free. Historically, for the S&P 500, this has been just under 50% of earnings. Currently, we expect the S&P to earn about 70 on a normalized basis, a number which is far below reported earnings due to our adjusting for record high profit margins. $70 X ½ / 1400 gives you a normalized free cash flow yield of approximately 2.5%.

The historical real growth rate of the S&P 500 (companies) is about 1.5%. Assuming an inflation rate of 2.5%, the forward rate of return on an investment in the S&P 500 is about 6.5% today (2.5% free cash flow yield plus 1.5% real growth plus 2.5% inflation).

For the growth part of the Forward Rate of Return calculation, GuruFocus uses the 5-year average growth rate of EBITDA per share as the growth rate, and the growth rate is always capped at 20%. For the Free Cash Flow we use per share data averaged over five years. The reason we use five years is because research shows that five years is the length of the typical business cycle.

Therefore, as of Jun26, Tyra Biosciences's Forward Rate of Return (Yacktman) % is

Forward Rate of Return (Yacktman) % (Jun26)=Normalized Free Cash Flow/Price+5-Year EBITDA Growth Rate
=0/31.94+0
=0.00 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Free Cash Flow within a report period can be affected by management's decisions of capital spending. Therefore, it is important to look at long term when it comes to Free Cash Flow.


Tyra Biosciences Free Cash Flow Related Terms


Tyra Biosciences Free Cash Flow Historical Data

* Premium members only.

The historical data trend for Tyra Biosciences's Free Cash Flow can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tyra Biosciences Free Cash Flow Chart

Tyra Biosciences Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Free Cash Flow
Get a 7-Day Free Trial -24.41 -50.84 -50.91 -70.44 -95.28

Tyra Biosciences Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Free Cash Flow Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -23.71 -22.42 -23.68 -32.66 -31.14
TYRA
33GF Score
Tyra Biosciences Inc TYRA
Free Cash Flow is just one metric. See GF Score™, valuation, warning signs, and more.
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Tyra Biosciences Free Cash Flow Calculation

Free Cash Flow is considered one of the most important parameters to measure a company's earnings power by value investors because it is not subject to estimates of Depreciation, Depletion and Amortization (DDA). However, when we look at the Free Cash Flow, we should look from a long term perspective, because any year's Free Cash Flow can be drastically affected by the spending on Property, Plant, & Equipment (PPE) of the business in that year. Over the long term, Free Cash Flow should give pretty good picture on the real earnings power of the company.

Tyra Biosciences's Free Cash Flow for the fiscal year that ended in Dec. 2025 is calculated as

Free Cash Flow (A: Dec. 2025 )=Cash Flow from Operations+Capital Expenditure
=-95.142+-0.141
=-95.28

Tyra Biosciences's Free Cash Flow for the quarter that ended in Jun. 2026 is calculated as

Free Cash Flow (Q: Jun. 2026 )=Cash Flow from Operations+Capital Expenditure
=-31.076+-0.066
=-31.14

Free Cash Flow for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-109.90 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Free Cash Flow →
What does a Free Cash Flow of $-109.90 Mil mean?
Tyra Biosciences (TYRA) has a Free Cash Flow of $-109.90 Mil as of Jun. 2026. Free cash flow represents the total amount of cash a company has on hand following operating and capital expenditures. View historial data for Tyra Biosciences and its competitors.
Is Tyra Biosciences' Free Cash Flow too high?
Tyra Biosciences' current Free Cash Flow is $-109.90 Mil. Overall, Tyra Biosciences has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Tyra Biosciences' Free Cash Flow compare to AVBP and TRAX?
Tyra Biosciences' Free Cash Flow of $-109.90 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Free Cash Flow for a Biotechnology company?
A good Free Cash Flow depends on the Biotechnology industry context. However, Free Cash Flow should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Free Cash Flow mean?
A high Free Cash Flow can signal that a stock is expensive relative to its fundamentals. Free cash flow represents the total amount of cash a company has on hand following operating and capital expenditures. View historial data for Tyra Biosciences and its competitors. Tyra Biosciences's current Free Cash Flow is $-109.90 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tyra Biosciences stock overvalued right now?
Tyra Biosciences (TYRA) has a current Free Cash Flow of $-109.90 Mil. The current Free Cash Flow is $-109.90 Mil. Tyra Biosciences' overall GF Score™ is 33/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Free Cash Flow calculated?
Free Cash Flow is calculated from a company's financial statements. For Tyra Biosciences (TYRA), the current Free Cash Flow is $-109.90 Mil as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Tyra Biosciences Business Description

Address 2656 State Street, Carlsbad, CA, USA, 92008
Tyra Biosciences Inc is a clinical-stage biotechnology company focused on developing next-generation precision medicines for large opportunities in targeted oncology and genetically defined conditions, harnessing the power of Fibroblast Growth Factor Receptor (FGFR) biology. The company's in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help to design and predict which product candidates may demonstrate the highest potency, selectivity, and tolerability in the clinic. The various drug candidates in the company's product pipeline are FGFR3, FGFR4/3, and FGFR1/2/3: three clinical-stage, novel small molecules designed to overcome the toxicity and resistance liabilities of first-generation pan-FGFR inhibitors.
33GF Score

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$22.01
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