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Tyra BiosciencesTYRA +1.17%28 EV-to-OCF is -14.37 as of Jul. 28, 2026. GuruFocus rates TYRA with a GF Score™ of 28/100. The stock has 2 warning signs investors should review. Among 1,407 Biotechnology companies, Tyra Biosciences ranks better than 76.4% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Tyra Biosciences's Enterprise Value is $1,469.39 Mil.
Tyra Biosciences's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was $-102.26 Mil. Therefore, Tyra Biosciences's EV-to-OCF for today is -14.37.
The historical rank and industry rank for Tyra Biosciences's EV-to-OCF or its related term are showing as below:
TYRA'
s EV-to-OCF Range Over the Past 10 Years
Min: -15.06 Med: 0 Max: -14.16
Current: -14.37
During the past 7 years, the highest EV-to-OCF of Tyra Biosciences was -14.16. The lowest was -15.06. And the median was .
TYRA's EV-to-OCF is ranked better than 76.4% of 1407
companies
in the Biotechnology industry
Industry Median: -3.31
vs TYRA: -14.37
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Tyra Biosciences's PE Ratio (TTM) for today is calculated as:
Tyra Biosciences's share price for today is $31.06.
Tyra Biosciences's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.180.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
Tyra Biosciences EV-to-OCF Related Terms
Tyra Biosciences EV-to-OCF Historical Data
* Premium members only.
The historical data trend for Tyra Biosciences's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Tyra Biosciences's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Tyra Biosciences EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Tyra Biosciences's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Tyra Biosciences's EV-to-OCF falls into.
Tyra Biosciences's current Enterprise Value is $1,469.39 Mil.
Tyra Biosciences's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-102.26 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Tyra Biosciences (TYRA) has a EV-to-OCF of -14.37 as of Jul. 28, 2026. According to the industry distribution chart, Tyra Biosciences ranks #332 out of 1407 companies in the Biotechnology industry, placing it in the top 23.6%.
Is Tyra Biosciences' EV-to-OCF too high?
Tyra Biosciences' current EV-to-OCF is -14.37. Based on the distribution chart, Tyra Biosciences ranks #332 out of 1407 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Tyra Biosciences has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Tyra Biosciences' EV-to-OCF compare to STOK and SNDX?
According to the Biotechnology industry distribution chart, Tyra Biosciences ranks #332 out of 1407 companies for EV-to-OCF. This places Tyra Biosciences in the top 24% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Tyra Biosciences's current EV-to-OCF is -14.37. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tyra Biosciences stock overvalued right now?
Tyra Biosciences (TYRA) has a current EV-to-OCF of -14.37. The current EV-to-OCF is -14.37. Tyra Biosciences' overall GF Score™ is 28/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Tyra Biosciences (TYRA), the current EV-to-OCF is -14.37 as of Jul. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Tyra Biosciences Inc is a clinical-stage biotechnology company focused on developing next-generation precision medicines for large opportunities in targeted oncology and genetically defined conditions, harnessing the power of Fibroblast Growth Factor Receptor (FGFR) biology. The company's in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help to design and predict which product candidates may demonstrate the highest potency, selectivity, and tolerability in the clinic. The various drug candidates in the company's product pipeline are FGFR3, FGFR4/3, and FGFR1/2/3: three clinical-stage, novel small molecules designed to overcome the toxicity and resistance liabilities of first-generation pan-FGFR inhibitors.
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