TYRA (Tyra Biosciences) EV-to-EBIT: -10.73 (As of Jul. 17, 2026)

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TYRA Tyra Biosciences Inc TYRA
28 GF Score
Price $32.11
! 2 Warning Signs
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What is Tyra Biosciences EV-to-EBIT?

Tyra Biosciences TYRA +1.65% 28 EV-to-EBIT is -10.73 as of Jul. 17, 2026. GuruFocus rates TYRA with a GF Score™ of 28/100. The stock has 2 warning signs investors should review. Among 372 Biotechnology companies, Tyra Biosciences ranks worse than 268816.94% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Tyra Biosciences's Enterprise Value is $1,533.02 Mil. Tyra Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-142.91 Mil. Therefore, Tyra Biosciences's EV-to-EBIT for today is -10.73.

The historical rank and industry rank for Tyra Biosciences's EV-to-EBIT or its related term are showing as below:

TYRA' s EV-to-EBIT Range Over the Past 10 Years
Min: -11.3   Med: 0   Max: 0
Current: -10.73

TYRA's EV-to-EBIT is ranked worse than
100% of 372 companies
in the Biotechnology industry
Industry Median: 13.35 vs TYRA: -10.73

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Tyra Biosciences's Enterprise Value for the quarter that ended in Mar. 2026 was $1,899.94 Mil. Tyra Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-142.91 Mil. Tyra Biosciences's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -7.52%.


Tyra Biosciences  (NAS:TYRA) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Tyra Biosciences's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Mar. 2026 ) =EBIT / Enterprise Value (Q: Mar. 2026 )
=-142.91/1899.938
=-7.52 %

Tyra Biosciences's Enterprise Value for the quarter that ended in Mar. 2026 was $1,899.94 Mil.
Tyra Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-142.91 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Tyra Biosciences EV-to-EBIT Related Terms


Tyra Biosciences EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Tyra Biosciences's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tyra Biosciences EV-to-EBIT Chart

Tyra Biosciences Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial -10.73 -1.24 -4.99 -3.55 -8.75

Tyra Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.59 -1.80 -3.79 -8.75 -13.29

TYRA vs SION, IOVA, SNDX: EV-to-EBIT Comparison

For the Biotechnology subindustry, Tyra Biosciences's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Tyra Biosciences EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Tyra Biosciences's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Tyra Biosciences's EV-to-EBIT falls into.


TYRA
28GF Score
Tyra Biosciences Inc TYRA
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
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Tyra Biosciences EV-to-EBIT Calculation

Tyra Biosciences's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=1533.021/-142.91
=-10.73

Tyra Biosciences's current Enterprise Value is $1,533.02 Mil.
Tyra Biosciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-142.91 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of -10.73 mean?
Tyra Biosciences (TYRA) has a EV-to-EBIT of -10.73 as of Jul. 17, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Tyra Biosciences and its competitors. According to the industry distribution chart, Tyra Biosciences ranks #999999 out of 372 companies in the Biotechnology industry.
Is Tyra Biosciences' EV-to-EBIT too high?
Tyra Biosciences' current EV-to-EBIT is -10.73. Based on the distribution chart, Tyra Biosciences ranks #999999 out of 372 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Tyra Biosciences has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Tyra Biosciences' EV-to-EBIT compare to SION and IOVA?
According to the Biotechnology industry distribution chart, Tyra Biosciences ranks #999999 out of 372 companies for EV-to-EBIT. This places Tyra Biosciences in the lower half of its industry. The industry median EV-to-EBIT is 13.35. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 13.35, based on 372 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Tyra Biosciences and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 13.35 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Tyra Biosciences's current EV-to-EBIT is -10.73. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tyra Biosciences stock overvalued right now?
Tyra Biosciences (TYRA) has a current EV-to-EBIT of -10.73. The current EV-to-EBIT is -10.73. Tyra Biosciences' overall GF Score™ is 28/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Tyra Biosciences (TYRA), the current EV-to-EBIT is -10.73 as of Jul. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Tyra Biosciences Business Description

Address 2656 State Street, Carlsbad, CA, USA, 92008
Tyra Biosciences Inc is a clinical-stage biotechnology company focused on developing next-generation precision medicines for large opportunities in targeted oncology and genetically defined conditions, harnessing the power of Fibroblast Growth Factor Receptor (FGFR) biology. The company's in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help to design and predict which product candidates may demonstrate the highest potency, selectivity, and tolerability in the clinic. The various drug candidates in the company's product pipeline are FGFR3, FGFR4/3, and FGFR1/2/3: three clinical-stage, novel small molecules designed to overcome the toxicity and resistance liabilities of first-generation pan-FGFR inhibitors.
28GF Score

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EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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