Epigenomics AG (FRA:ECX) EV-to-OCF: -22.10 (As of Aug. 16, 2026)

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FRA:ECX Epigenomics AG FRA:ECX
20 GF Score
Price €0.91
GF Value €0.09
Valuation Significantly Overvalued
! 3 Warning Signs
View Full Analysis

What is Epigenomics AG EV-to-OCF?

Epigenomics AG FRA:ECX -8.08% 20 EV-to-OCF is -22.10 as of Aug. 16, 2026. GuruFocus rates FRA:ECX with a GF Score™ of 20/100 and a GF Value™ of €0.09 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 212 Medical Diagnostics & Research companies, Epigenomics AG ranks better than 88.68% on this metric.

EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Epigenomics AG's Enterprise Value is €11.78 Mil. Epigenomics AG's Cash Flow from Operations for the trailing twelve months (TTM) ended in Dec. 2025 was €-0.53 Mil. Therefore, Epigenomics AG's EV-to-OCF for today is -22.10.

The historical rank and industry rank for Epigenomics AG's EV-to-OCF or its related term are showing as below:

FRA:ECX' s EV-to-OCF Range Over the Past 10 Years
Min: -22.88   Med: -1.94   Max: 4.67
Current: -22.1

During the past 13 years, the highest EV-to-OCF of Epigenomics AG was 4.67. The lowest was -22.88. And the median was -1.94.

FRA:ECX's EV-to-OCF is ranked better than
88.68% of 212 companies
in the Medical Diagnostics & Research industry
Industry Median: 6.235 vs FRA:ECX: -22.10

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-08-16), Epigenomics AG's stock price is €0.91. Epigenomics AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was €-0.351. Therefore, Epigenomics AG's PE Ratio (TTM) for today is At Loss.


Epigenomics AG  (FRA:ECX) EV-to-OCF Explanation

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Epigenomics AG's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=0.91/-0.351
=At Loss

Epigenomics AG's share price for today is €0.91.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Epigenomics AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was €-0.351.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.


Epigenomics AG EV-to-OCF Related Terms


Epigenomics AG EV-to-OCF Historical Data

* Premium members only.

The historical data trend for Epigenomics AG's EV-to-OCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Epigenomics AG EV-to-OCF Chart

Epigenomics AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-OCF
Get a 7-Day Free Trial Premium Member Only Premium Member Only 2.94 -1.09 -1.99 -9.51 -22.06

Epigenomics AG Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
EV-to-OCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.99 0.00 -9.51 0.00 -22.06

FRA:ECX vs TMO, DHR, IDXX: EV-to-OCF Comparison

For the Diagnostics & Research subindustry, Epigenomics AG's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Epigenomics AG EV-to-OCF vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Epigenomics AG's EV-to-OCF distribution charts can be found below:

* The bar in red indicates where Epigenomics AG's EV-to-OCF falls into.


FRA:ECX
20GF Score
Epigenomics AG FRA:ECX
EV-to-OCF is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Epigenomics AG EV-to-OCF Calculation

Epigenomics AG's EV-to-OCF for today is calculated as:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=11.780/-0.533
=-22.10

Epigenomics AG's current Enterprise Value is €11.78 Mil.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Epigenomics AG's Cash Flow from Operations for the trailing twelve months (TTM) ended in Dec. 2025 was €-0.53 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-OCF →
What does a EV-to-OCF of -22.10 mean?
Epigenomics AG (FRA:ECX) has a EV-to-OCF of -22.10 as of Aug. 16, 2026. According to the industry distribution chart, Epigenomics AG ranks #24 out of 212 companies in the Medical Diagnostics & Research industry, placing it in the top 11.3%.
Is Epigenomics AG's EV-to-OCF too high?
Epigenomics AG's current EV-to-OCF is -22.10. Based on the distribution chart, Epigenomics AG ranks #24 out of 212 companies in the Medical Diagnostics & Research industry, which is in the top quartile — a strong position relative to peers. Overall, Epigenomics AG has a GF Score™ of 20/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Epigenomics AG's EV-to-OCF compare to TMO and DHR?
According to the Medical Diagnostics & Research industry distribution chart, Epigenomics AG ranks #24 out of 212 companies for EV-to-OCF. This places Epigenomics AG in the top 11% of its industry — outperforming the majority of peers. The industry median EV-to-OCF is 6.24. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Medical Diagnostics & Research company?
The median EV-to-OCF among Medical Diagnostics & Research companies is 6.24, based on 212 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-OCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. For the Medical Diagnostics & Research industry, the median EV-to-OCF is 6.24 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Epigenomics AG's current EV-to-OCF is -22.10. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Epigenomics AG stock overvalued right now?
Based on GuruFocus' analysis, Epigenomics AG (FRA:ECX) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.09, compared to a current price of €0.91 — trading 911.1% above its estimated fair value. The current EV-to-OCF is -22.10. Epigenomics AG's overall GF Score™ is 20/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Epigenomics AG (FRA:ECX), the current EV-to-OCF is -22.10 as of Aug. 16, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Epigenomics AG (FRA:ECX) Overvalued in 2026?

Based on GuruFocus' analysis, Epigenomics AG stock appears to be overvalued. The current stock price of €0.91 is trading 911.1% above its estimated GF Value™ of €0.09. GuruFocus considers Epigenomics AG to be Significantly Overvalued.

Key valuation signals for FRA:ECX:

  • EV-to-OCF: -22.10
  • GF Value™: €0.09 vs. price of €0.91 (911.1% above fair value)
  • GF Score™: 20/100 with 3 warning signs

No single metric tells the full story. See the FRA:ECX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Epigenomics AG Business Description

Other Exchanges ECX:Germany
Address Ziegelhauser Landstrabe 3, Heidelberg, BW, DEU, 69120
Epigenomics AG is a molecular diagnostics company, that focuses on developing and commercializing in vitro diagnostic liquid biopsy tests for the screening, early detection, and diagnosis of cancer. The company develops and markets procedures and devices for the production in quantity of particular epigenetic parameters such as DNA methylation patterns as well as the information technology bases necessary for their procurement and evaluation. It is engaged in the development of novel molecular diagnostic products for cancer. The company products include Epi proColon, Epi BiSKit, HCCBloodTest, and Epi proLung. The company operates in Europe, Asia, and North America, majority of its revenue derives from Asia.
20GF Score

Get the complete analysis for FRA:ECX

EV-to-OCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€0.91
Price
€0.09
GF Value