Epigenomics AG (FRA:ECX) ROA %: -1.87% (As of Dec. 2025)


FRA:ECX Epigenomics AG FRA:ECX
13 GF Score
Price €0.87
GF Value €0.09
Valuation Significantly Overvalued
! 3 Warning Signs
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What is Epigenomics AG ROA %?

Epigenomics AG FRA:ECX 13 ROA % is -1.87% as of Dec. 2025. GuruFocus rates FRA:ECX with a GF Score™ of 13/100 and a GF Value™ of €0.09 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 214 Medical Diagnostics & Research companies, Epigenomics AG ranks worse than 52.8% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Epigenomics AG's annualized Net Income for the quarter that ended in Dec. 2025 was €-0.22 Mil. Epigenomics AG's average Total Assets over the quarter that ended in Dec. 2025 was €11.74 Mil. Therefore, Epigenomics AG's annualized ROA % for the quarter that ended in Dec. 2025 was -1.87%.

The historical rank and industry rank for Epigenomics AG's ROA % or its related term are showing as below:

FRA:ECX' s ROA % Range Over the Past 10 Years
Min: -112.44   Med: -57.45   Max: -2.67
Current: -2.67

During the past 13 years, Epigenomics AG's highest ROA % was -2.67%. The lowest was -112.44%. And the median was -57.45%.

FRA:ECX's ROA % is ranked worse than
52.8% of 214 companies
in the Medical Diagnostics & Research industry
Industry Median: -2.11 vs FRA:ECX: -2.67

Epigenomics AG  (FRA:ECX) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Dec. 2025 )
=Net Income/Total Assets
=-0.22/11.7395
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-0.22 / 0.04)*(0.04 / 11.7395)
=Net Margin %*Asset Turnover
=-550 %*0.0034
=-1.87 %

Note: The Net Income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Epigenomics AG ROA % Related Terms


Epigenomics AG ROA % Historical Data

* Premium members only.

The historical data trend for Epigenomics AG's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Epigenomics AG ROA % Chart

Epigenomics AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -15.44 -89.54 -33.27 -27.14 -2.68

Epigenomics AG Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 28.79 -12.80 -42.80 -3.44 -1.87

FRA:ECX vs TMO, DHR, IDXX: ROA % Comparison

For the Diagnostics & Research subindustry, Epigenomics AG's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Epigenomics AG ROA % vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Epigenomics AG's ROA % distribution charts can be found below:

* The bar in red indicates where Epigenomics AG's ROA % falls into.


FRA:ECX
13GF Score
Epigenomics AG FRA:ECX
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Epigenomics AG ROA % Calculation

Epigenomics AG's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-0.314/( (11.852+11.615)/ 2 )
=-0.314/11.7335
=-2.68 %

Epigenomics AG's annualized ROA % for the quarter that ended in Dec. 2025 is calculated as:

ROA %=Net Income (Q: Dec. 2025 )/( (Total Assets (Q: Jun. 2025 )+Total Assets (Q: Dec. 2025 ))/ count )
=-0.22/( (11.864+11.615)/ 2 )
=-0.22/11.7395
=-1.87 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is two times the semi-annual (Dec. 2025) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -1.87% mean?
Epigenomics AG (FRA:ECX) has a ROA % of -1.87% as of Dec. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Epigenomics AG and its competitors. According to the industry distribution chart, Epigenomics AG ranks #113 out of 214 companies in the Medical Diagnostics & Research industry, placing it in the top 52.8%.
Is Epigenomics AG's ROA % too high?
Epigenomics AG's current ROA % is -1.87%. Based on the distribution chart, Epigenomics AG ranks #113 out of 214 companies in the Medical Diagnostics & Research industry, which is below the industry midpoint. Overall, Epigenomics AG has a GF Score™ of 13/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Epigenomics AG's ROA % compare to TMO and DHR?
According to the Medical Diagnostics & Research industry distribution chart, Epigenomics AG ranks #113 out of 214 companies for ROA %. This places Epigenomics AG in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Medical Diagnostics & Research company?
A good ROA % depends on the Medical Diagnostics & Research industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Epigenomics AG and its competitors. Epigenomics AG's current ROA % is -1.87%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Epigenomics AG stock overvalued right now?
Based on GuruFocus' analysis, Epigenomics AG (FRA:ECX) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.09, compared to a current price of €0.87 — trading 866.7% above its estimated fair value. The current ROA % is -1.87%. Epigenomics AG's overall GF Score™ is 13/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Epigenomics AG (FRA:ECX), the current ROA % is -1.87% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Epigenomics AG (FRA:ECX) Overvalued in 2026?

Based on GuruFocus' analysis, Epigenomics AG stock appears to be overvalued. The current stock price of €0.87 is trading 866.7% above its estimated GF Value™ of €0.09. GuruFocus considers Epigenomics AG to be Significantly Overvalued.

Key valuation signals for FRA:ECX:

  • ROA %: -1.87%
  • GF Value™: €0.09 vs. price of €0.87 (866.7% above fair value)
  • GF Score™: 13/100 with 3 warning signs

No single metric tells the full story. See the FRA:ECX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Epigenomics AG Business Description

Other Exchanges ECX:Germany
Address Ziegelhauser Landstrabe 3, Heidelberg, BW, DEU, 69120
Epigenomics AG is a molecular diagnostics company, that focuses on developing and commercializing in vitro diagnostic liquid biopsy tests for the screening, early detection, and diagnosis of cancer. The company develops and markets procedures and devices for the production in quantity of particular epigenetic parameters such as DNA methylation patterns as well as the information technology bases necessary for their procurement and evaluation. It is engaged in the development of novel molecular diagnostic products for cancer. The company products include Epi proColon, Epi BiSKit, HCCBloodTest, and Epi proLung. The company operates in Europe, Asia, and North America, majority of its revenue derives from Asia.
13GF Score

Get the complete analysis for FRA:ECX

ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€0.87
Price
€0.09
GF Value