Epigenomics AG (FRA:ECX) Piotroski F-Score: 5 (As of Jul. 01, 2026) — 67% Above Median


FRA:ECX Epigenomics AG FRA:ECX
13 GF Score
Price €0.87
GF Value €0.09
Valuation Significantly Overvalued
! 3 Warning Signs
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What is Epigenomics AG Piotroski F-Score?

Epigenomics AG FRA:ECX 13 Piotroski F-Score is 5 as of Jul. 01, 2026, which is 67% above its 10-year median of 3.00. GuruFocus rates FRA:ECX with a GF Score™ of 13/100 and a GF Value™ of €0.09 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 210 Medical Diagnostics & Research companies, Epigenomics AG ranks better than 64.76% on this metric.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Epigenomics AG has an F-score of 5 indicating the company's financial situation is typical for a stable company.

The historical rank and industry rank for Epigenomics AG's Piotroski F-Score or its related term are showing as below:

FRA:ECX' s Piotroski F-Score Range Over the Past 10 Years
Min: 2   Med: 3   Max: 5
Current: 5

During the past 13 years, the highest Piotroski F-Score of Epigenomics AG was 5. The lowest was 2. And the median was 3.

Epigenomics AG  (FRA:ECX) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Epigenomics AG Piotroski F-Score Related Terms


Epigenomics AG Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Epigenomics AG's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Epigenomics AG Piotroski F-Score Chart

Epigenomics AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial Premium Member Only Premium Member Only 5.00 2.00 2.00 3.00 5.00

Epigenomics AG Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.00 0.00 3.00 3.00 5.00

FRA:ECX vs TMO, DHR, IDXX: Piotroski F-Score Comparison

For the Diagnostics & Research subindustry, Epigenomics AG's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Epigenomics AG Piotroski F-Score vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Epigenomics AG's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Epigenomics AG's Piotroski F-Score falls into.


FRA:ECX
13GF Score
Epigenomics AG FRA:ECX
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Dec25) TTM:Last Year (Dec24) TTM:
Net Income was €-0.31 Mil.
Cash Flow from Operations was €-0.53 Mil.
Revenue was €0.02 Mil.
Gross Profit was €0.02 Mil.
Average Total Assets from the begining of this year (Dec24)
to the end of this year (Dec25) was (11.852 + 11.615) / 2 = €11.7335 Mil.
Total Assets at the begining of this year (Dec24) was €11.85 Mil.
Long-Term Debt & Capital Lease Obligation was €11.38 Mil.
Total Current Assets was €0.44 Mil.
Total Current Liabilities was €0.00 Mil.
Net Income was €-3.35 Mil.

Revenue was €0.00 Mil.
Gross Profit was €0.00 Mil.
Average Total Assets from the begining of last year (Dec23)
to the end of last year (Dec24) was (12.845 + 11.852) / 2 = €12.3485 Mil.
Total Assets at the begining of last year (Dec23) was €12.85 Mil.
Long-Term Debt & Capital Lease Obligation was €11.38 Mil.
Total Current Assets was €0.99 Mil.
Total Current Liabilities was €0.01 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Epigenomics AG's current Net Income (TTM) was -0.31. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Epigenomics AG's current Cash Flow from Operations (TTM) was -0.53. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Dec24)
=-0.314/11.852
=-0.02649342

ROA (Last Year)=Net Income/Total Assets (Dec23)
=-3.352/12.845
=-0.26095757

Epigenomics AG's return on assets of this year was -0.02649342. Epigenomics AG's return on assets of last year was -0.26095757. ==> This year is higher. ==> Score 1.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Epigenomics AG's current Net Income (TTM) was -0.31. Epigenomics AG's current Cash Flow from Operations (TTM) was -0.53. ==> -0.53 <= -0.31 ==> CFROA <= ROA ==> Score 0.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Dec25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec24 to Dec25
=11.381/11.7335
=0.96995781

Gearing (Last Year: Dec24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec23 to Dec24
=11.382/12.3485
=0.92173138

Epigenomics AG's gearing of this year was 0.96995781. Epigenomics AG's gearing of last year was 0.92173138. ==> Last year is lower than this year ==> Score 0.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Dec25)=Total Current Assets/Total Current Liabilities
=0.441/0.004
=110.25

Current Ratio (Last Year: Dec24)=Total Current Assets/Total Current Liabilities
=0.99/0.012
=82.5

Epigenomics AG's current ratio of this year was 110.25. Epigenomics AG's current ratio of last year was 82.5. ==> This year's current ratio is higher. ==> Score 1.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Epigenomics AG's number of shares in issue this year was 0.877. Epigenomics AG's number of shares in issue last year was 0.877. ==> There is smaller number of shares in issue this year, or the same. ==> Score 1.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=0.024/0.024
=1

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=0/0
=

Epigenomics AG's gross margin of this year was 1. Epigenomics AG's gross margin of last year was . ==> This year's gross margin is higher. ==> Score 1.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Dec24)
=0.024/11.852
=0.00202497

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Dec23)
=0/12.845
=0

Epigenomics AG's asset turnover of this year was 0.00202497. Epigenomics AG's asset turnover of last year was 0. ==> This year's asset turnover is higher. ==> Score 1.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+1+0+0+1+1+1+1
=5

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Epigenomics AG has an F-score of 5 indicating the company's financial situation is typical for a stable company.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 5 mean?
Epigenomics AG (FRA:ECX) has a Piotroski F-Score of 5 as of Jul. 01, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Epigenomics AG and its competitors. This is 67% above median its historical median of 3.00. Over the past decade, Epigenomics AG's Piotroski F-Score has ranged from 2.00 to 5.00. According to the industry distribution chart, Epigenomics AG ranks #74 out of 210 companies in the Medical Diagnostics & Research industry, placing it in the top 35.2%.
Is Epigenomics AG's Piotroski F-Score too high?
Epigenomics AG's current Piotroski F-Score of 5 is 67% above median its 10-year median of 3.00. Over the past 10 years, this metric has ranged from a low of 2.00 to a high of 5.00. The Medical Diagnostics & Research industry median Piotroski F-Score is 5.00. Epigenomics AG's value of 5 is 0% at this industry median. Based on the distribution chart, Epigenomics AG ranks #74 out of 210 companies in the Medical Diagnostics & Research industry, which is above the industry midpoint. Overall, Epigenomics AG has a GF Score™ of 13/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Epigenomics AG's Piotroski F-Score compare to TMO and DHR?
According to the Medical Diagnostics & Research industry distribution chart, Epigenomics AG ranks #74 out of 210 companies for Piotroski F-Score. This puts Epigenomics AG in the upper half of its industry. The industry median Piotroski F-Score is 5.00. Epigenomics AG's value of 5 is 0% at this benchmark. Historically, Epigenomics AG's own Piotroski F-Score has ranged from 2.00 to 5.00 over the past decade. While the company's 10-year median is 3.00 vs. the industry median of 5.00, Epigenomics AG has consistently been at the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Medical Diagnostics & Research company?
The median Piotroski F-Score among Medical Diagnostics & Research companies is 5.00, based on 210 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Epigenomics AG's current Piotroski F-Score of 5 is 0% at the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Epigenomics AG and its competitors. For the Medical Diagnostics & Research industry, the median Piotroski F-Score is 5.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Epigenomics AG's current Piotroski F-Score is 5, which is 67% above median its own 10-year median of 3.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Epigenomics AG stock overvalued right now?
Based on GuruFocus' analysis, Epigenomics AG (FRA:ECX) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.09, compared to a current price of €0.87 — trading 866.7% above its estimated fair value. The current Piotroski F-Score is 5, which is 67% above median its 10-year median of 3.00 and 0% at the Medical Diagnostics & Research industry median of 5.00. Epigenomics AG's overall GF Score™ is 13/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Epigenomics AG (FRA:ECX), the current Piotroski F-Score is 5 as of Jul. 01, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Epigenomics AG (FRA:ECX) Overvalued in 2026?

Based on GuruFocus' analysis, Epigenomics AG stock appears to be overvalued. The current stock price of €0.87 is trading 866.7% above its estimated GF Value™ of €0.09. GuruFocus considers Epigenomics AG to be Significantly Overvalued.

Key valuation signals for FRA:ECX:

  • Piotroski F-Score: 5 (67% above median its 10-year median of 3.00)
  • GF Value™: €0.09 vs. price of €0.87 (866.7% above fair value)
  • GF Score™: 13/100 with 3 warning signs
  • Industry Position: 0% at the Medical Diagnostics & Research median (#74 of 210)

No single metric tells the full story. See the FRA:ECX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Epigenomics AG Business Description

Other Exchanges ECX:Germany
Address Ziegelhauser Landstrabe 3, Heidelberg, BW, DEU, 69120
Epigenomics AG is a molecular diagnostics company, that focuses on developing and commercializing in vitro diagnostic liquid biopsy tests for the screening, early detection, and diagnosis of cancer. The company develops and markets procedures and devices for the production in quantity of particular epigenetic parameters such as DNA methylation patterns as well as the information technology bases necessary for their procurement and evaluation. It is engaged in the development of novel molecular diagnostic products for cancer. The company products include Epi proColon, Epi BiSKit, HCCBloodTest, and Epi proLung. The company operates in Europe, Asia, and North America, majority of its revenue derives from Asia.
13GF Score

Get the complete analysis for FRA:ECX

Piotroski F-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€0.87
Price
€0.09
GF Value