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Roche Holding AGXSWX:RO -1.41%76 EV-to-OCF is 15.14 as of Jul. 14, 2026, which is 11% above its 10-year median of 13.70. GuruFocus rates XSWX:RO with a GF Score™ of 76/100 and a GF Value™ of CHF268.98 (Modestly Overvalued). The stock has 7 warning signs investors should review. Among 1,008 Drug Manufacturers companies, Roche Holding AG ranks worse than 61.31% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Roche Holding AG's Enterprise Value is CHF285,491 Mil.
Roche Holding AG's Cash Flow from Operations for the trailing twelve months (TTM) ended in Dec. 2025 was CHF18,852 Mil. Therefore, Roche Holding AG's EV-to-OCF for today is 15.14.
The historical rank and industry rank for Roche Holding AG's EV-to-OCF or its related term are showing as below:
XSWX:RO'
s EV-to-OCF Range Over the Past 10 Years
Min: 10.44 Med: 13.7 Max: 18
Current: 15.39
During the past 13 years, the highest EV-to-OCF of Roche Holding AG was 18.00. The lowest was 10.44. And the median was 13.70.
XSWX:RO's EV-to-OCF is ranked worse than 61.31% of 1008
companies
in the Drug Manufacturers industry
Industry Median: 10.63
vs XSWX:RO: 15.39
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Roche Holding AG's PE Ratio (TTM) for today is calculated as:
Roche Holding AG's share price for today is CHF336.20.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Roche Holding AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was CHF16.040.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
Roche Holding AG EV-to-OCF Related Terms
Roche Holding AG EV-to-OCF Historical Data
* Premium members only.
The historical data trend for Roche Holding AG's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Drug Manufacturers - General subindustry, Roche Holding AG's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Roche Holding AG EV-to-OCF vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Roche Holding AG's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Roche Holding AG's EV-to-OCF falls into.
Roche Holding AG's current Enterprise Value is CHF285,491 Mil.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Roche Holding AG's Cash Flow from Operations for the trailing twelve months (TTM) ended in Dec. 2025 was CHF18,852 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Roche Holding AG (XSWX:RO) has a EV-to-OCF of 15.14 as of Jul. 14, 2026. This is 11% above median its historical median of 13.70. Over the past decade, Roche Holding AG's EV-to-OCF has ranged from 10.44 to 18.00. According to the industry distribution chart, Roche Holding AG ranks #618 out of 1008 companies in the Drug Manufacturers industry, placing it in the top 61.3%.
Is Roche Holding AG's EV-to-OCF too high?
Roche Holding AG's current EV-to-OCF of 15.14 is 11% above median its 10-year median of 13.70. Over the past 10 years, this metric has ranged from a low of 10.44 to a high of 18.00. The Drug Manufacturers industry median EV-to-OCF is 10.63. Roche Holding AG's value of 15.14 is 42.4% above this industry median. Based on the distribution chart, Roche Holding AG ranks #618 out of 1008 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Roche Holding AG has a GF Score™ of 76/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Roche Holding AG's EV-to-OCF compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Roche Holding AG ranks #618 out of 1008 companies for EV-to-OCF. This places Roche Holding AG in the lower half of its industry. The industry median EV-to-OCF is 10.63. Roche Holding AG's value of 15.14 is 42.4% above this benchmark. Historically, Roche Holding AG's own EV-to-OCF has ranged from 10.44 to 18.00 over the past decade. While the company's 10-year median is 13.70 vs. the industry median of 10.63, Roche Holding AG has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Drug Manufacturers company?
The median EV-to-OCF among Drug Manufacturers companies is 10.63, based on 1,008 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-OCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Roche Holding AG's current EV-to-OCF of 15.14 is 42.4% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. For the Drug Manufacturers industry, the median EV-to-OCF is 10.63 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Roche Holding AG's current EV-to-OCF is 15.14, which is 11% above median its own 10-year median of 13.70. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Roche Holding AG stock overvalued right now?
Based on GuruFocus' analysis, Roche Holding AG (XSWX:RO) is currently considered Modestly Overvalued. The stock's GF Value™ is CHF268.98, compared to a current price of CHF336.20 — trading 25% above its estimated fair value. The current EV-to-OCF is 15.14, which is 11% above median its 10-year median of 13.70 and 42.4% above the Drug Manufacturers industry median of 10.63. Roche Holding AG's overall GF Score™ is 76/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Roche Holding AG (XSWX:RO), the current EV-to-OCF is 15.14 as of Jul. 14, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Roche Holding AG (XSWX:RO) Overvalued in 2026?
Based on GuruFocus' analysis, Roche Holding AG stock appears to be overvalued.
The current stock price of CHF336.20 is trading 25% above its estimated GF Value™ of CHF268.98.
GuruFocus considers Roche Holding AG to be Modestly Overvalued.
Key valuation signals for XSWX:RO:
EV-to-OCF: 15.14 (11% above median its 10-year median of 13.70)
GF Value™: CHF268.98 vs. price of CHF336.20 (25% above fair value)
Industry Position: 42.4% above the Drug Manufacturers median (#618 of 1008)
No single metric tells the full story. See the XSWX:RO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 40% of pharmaceutical sales, and centralized and point-of-care diagnostics for two-thirds of diagnostic-related sales.
76GF Score
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