Roche Holding AG (XSWX:RO) 5-Year ROIIC % : -4.99% (As of Dec. 2025)


XSWX:RO Roche Holding AG XSWX:RO
77 GF Score
Price CHF342.00
GF Value CHF269.42
Valuation Modestly Overvalued
! 7 Warning Signs
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What is Roche Holding AG 5-Year ROIIC %?

Roche Holding AG XSWX:RO -0.47% 77 5-Year ROIIC % is -4.99 as of Dec. 2025. GuruFocus rates XSWX:RO with a GF Score™ of 77/100 and a GF Value™ of CHF269.42 (Modestly Overvalued). The stock has 7 warning signs investors should review. Among 897 Drug Manufacturers companies, Roche Holding AG ranks worse than 64.21% on this metric.

5-Year Return on Invested Incremental Capital (5-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 5-year. Roche Holding AG's 5-Year ROIIC % for the quarter that ended in Dec. 2025 was -4.99%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Roche Holding AG's 5-Year ROIIC % or its related term are showing as below:

XSWX:RO's 5-Year ROIIC % is ranked worse than
64.21% of 897 companies
in the Drug Manufacturers industry
Industry Median: 2.4 vs XSWX:RO: -4.99

Roche Holding AG  (XSWX:RO) 5-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Roche Holding AG 5-Year ROIIC % Related Terms


Roche Holding AG 5-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Roche Holding AG's 5-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Roche Holding AG 5-Year ROIIC % Chart

Roche Holding AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
5-Year ROIIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 22.00 37.88 16.21 -35.52 -4.99

Roche Holding AG Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
5-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 16.21 0.00 -35.52 0.00 -4.99

XSWX:RO vs LLY, JNJ, ABBV: 5-Year ROIIC % Comparison

For the Drug Manufacturers - General subindustry, Roche Holding AG's 5-Year ROIIC %, along with its competitors' market caps and 5-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Roche Holding AG 5-Year ROIIC % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Roche Holding AG's 5-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Roche Holding AG's 5-Year ROIIC % falls into.


XSWX:RO
77GF Score
Roche Holding AG XSWX:RO
5-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Roche Holding AG 5-Year ROIIC % Calculation

Roche Holding AG's 5-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

5-Year ROIIC %=5-Year Incremental Net Operating Profit After Taxes (NOPAT)**/5-Year Incremental Invested Capital**
=( 15020.988 (Dec. 2025) - 15552.0141 (Dec. 2020) )/( 81067 (Dec. 2025) - 70435 (Dec. 2020) )
=-531.0261/10632
=-4.99%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 5-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 5-Year ROIIC % →
What does a 5-Year ROIIC % of -4.99 mean?
Roche Holding AG (XSWX:RO) has a 5-Year ROIIC % of -4.99 as of Dec. 2025. 5-Year ROIIC % measures the change in earnings as a percentage of change in investment over 5-year. View historical data on Roche Holding AG and its competitors. According to the industry distribution chart, Roche Holding AG ranks #576 out of 897 companies in the Drug Manufacturers industry, placing it in the top 64.2%.
Is Roche Holding AG's 5-Year ROIIC % too high?
Roche Holding AG's current 5-Year ROIIC % is -4.99. Based on the distribution chart, Roche Holding AG ranks #576 out of 897 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Roche Holding AG has a GF Score™ of 77/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Roche Holding AG's 5-Year ROIIC % compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Roche Holding AG ranks #576 out of 897 companies for 5-Year ROIIC %. This places Roche Holding AG in the lower half of its industry. The industry median 5-Year ROIIC % is 2.40. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 5-Year ROIIC % for a Drug Manufacturers company?
The median 5-Year ROIIC % among Drug Manufacturers companies is 2.40, based on 897 companies in the industry. Companies in the top quartile (top 25%) have a 5-Year ROIIC % significantly above this median, while those in the bottom quartile fall well below. However, 5-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 5-Year ROIIC % mean?
A high 5-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 5-Year ROIIC % measures the change in earnings as a percentage of change in investment over 5-year. View historical data on Roche Holding AG and its competitors. For the Drug Manufacturers industry, the median 5-Year ROIIC % is 2.40 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Roche Holding AG's current 5-Year ROIIC % is -4.99. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Roche Holding AG stock overvalued right now?
Based on GuruFocus' analysis, Roche Holding AG (XSWX:RO) is currently considered Modestly Overvalued. The stock's GF Value™ is CHF269.42, compared to a current price of CHF342.00 — trading 26.9% above its estimated fair value. The current 5-Year ROIIC % is -4.99. Roche Holding AG's overall GF Score™ is 77/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 5-Year ROIIC % calculated?
5-Year ROIIC % is calculated from a company's financial statements. For Roche Holding AG (XSWX:RO), the current 5-Year ROIIC % is -4.99 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Roche Holding AG (XSWX:RO) Overvalued in 2026?

Based on GuruFocus' analysis, Roche Holding AG stock appears to be overvalued. The current stock price of CHF342.00 is trading 26.9% above its estimated GF Value™ of CHF269.42. GuruFocus considers Roche Holding AG to be Modestly Overvalued.

Key valuation signals for XSWX:RO:

  • 5-Year ROIIC %: -4.99
  • GF Value™: CHF269.42 vs. price of CHF342.00 (26.9% above fair value)
  • GF Score™: 77/100 with 7 warning signs

No single metric tells the full story. See the XSWX:RO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Roche Holding AG Business Description

Address Grenzacherstrasse 124, Basel, CHE, 4070
Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 40% of pharmaceutical sales, and centralized and point-of-care diagnostics for two-thirds of diagnostic-related sales.
77GF Score

Get the complete analysis for XSWX:RO

5-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

CHF342.00
Price
CHF269.42
GF Value