PRLD (Prelude Therapeutics) YoY EPS Growth: 69.05% (As of Mar. 2026)

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PRLD Prelude Therapeutics Inc PRLD
22 GF Score
Price $4.49
! 3 Warning Signs
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What is Prelude Therapeutics YoY EPS Growth?

Prelude Therapeutics PRLD +2.28% 22 YoY EPS Growth is 69.05% as of Mar. 2026. GuruFocus rates PRLD with a GF Score™ of 22/100. The stock has 3 warning signs investors should review.

YoY EPS Growth is the percentage change of Earnings per Share (Diluted) over the past twelve months. Prelude Therapeutics's YoY EPS Growth for the quarter that ended in Mar. 2026 was 69.05%.

Prelude Therapeutics's Earnings per Share (Diluted) for the three months ended in Mar. 2026 was $-0.13.

Prelude Therapeutics YoY EPS Growth Historical Data

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The historical data trend for Prelude Therapeutics's YoY EPS Growth can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Prelude Therapeutics YoY EPS Growth Chart

Prelude Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
YoY EPS Growth
Get a 7-Day Free Trial 46.71 -0.41 17.21 16.83 23.21

Prelude Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
YoY EPS Growth Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 10.87 39.53 47.37 69.05
PRLD
22GF Score
Prelude Therapeutics Inc PRLD
YoY EPS Growth is just one metric. See GF Score™, valuation, warning signs, and more.
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Prelude Therapeutics YoY EPS Growth Calculation

YoY EPS Growth is the percentage change of Earnings per Share (Diluted) over the past twelve months.

Prelude Therapeutics's YoY EPS Growth for the fiscal year that ended in Dec. 2025 is calculated as:

YoY EPS Growth (A: Dec. 2025 )
=(Earnings per Share (Diluted) (A: Dec. 2025 )-Earnings per Share (Diluted) (A: Dec. 2024 ))/ | Earnings per Share (Diluted) (A: Dec. 2024 ) |
=(-1.29--1.68)/ | -1.68 |
=23.21 %

Prelude Therapeutics's YoY EPS Growth for the quarter that ended in Mar. 2026 is calculated as:

YoY EPS Growth (Q: Mar. 2026 )
=(Earnings per Share (Diluted) (Q: Mar. 2026 )-Earnings per Share (Diluted) (Q: Mar. 2025 )) / | Earnings per Share (Diluted) (Q: Mar. 2025 )) |
=(-0.13--0.42)/ | -0.42 |
=69.05 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about YoY EPS Growth →
What does a YoY EPS Growth of 69.05% mean?
Prelude Therapeutics (PRLD) has a YoY EPS Growth of 69.05% as of Mar. 2026. YoY EPS Growth is the percentage change of EPS over the past 12-month. View historical data for Prelude Therapeutics and its competitors.
Is Prelude Therapeutics' YoY EPS Growth too high?
Prelude Therapeutics' current YoY EPS Growth is 69.05%. Overall, Prelude Therapeutics has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does Prelude Therapeutics' YoY EPS Growth compare to PROK and ZNTL?
Prelude Therapeutics' YoY EPS Growth of 69.05% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good YoY EPS Growth for a Biotechnology company?
A good YoY EPS Growth depends on the Biotechnology industry context. However, YoY EPS Growth should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high YoY EPS Growth mean?
A high YoY EPS Growth can signal that a stock is expensive relative to its fundamentals. YoY EPS Growth is the percentage change of EPS over the past 12-month. View historical data for Prelude Therapeutics and its competitors. Prelude Therapeutics's current YoY EPS Growth is 69.05%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Prelude Therapeutics stock overvalued right now?
Prelude Therapeutics (PRLD) has a current YoY EPS Growth of 69.05%. The current YoY EPS Growth is 69.05%. Prelude Therapeutics' overall GF Score™ is 22/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is YoY EPS Growth calculated?
YoY EPS Growth is calculated from a company's financial statements. For Prelude Therapeutics (PRLD), the current YoY EPS Growth is 69.05% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Prelude Therapeutics Business Description

Address 175 Innovation Boulevard, Wilmington, DE, USA, 19805
Prelude Therapeutics Incorp is a precision oncology company developing medicines in areas of high unmet need for cancer patients. Its pipeline features selective KAT6A degraders and mutant selective JAK2V617F JH2 inhibitors, new approaches to clinically validated targets with transformative potential for patients. The company is also leveraging its expertise in targeted protein degradation to discover and develop next-generation degrader antibody conjugates (DACs) with novel payloads.
22GF Score

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YoY EPS Growth is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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