PRLD (Prelude Therapeutics) Pre-Tax Income: $-77.80 Mil (TTM As of Mar. 2026)

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PRLD Prelude Therapeutics Inc PRLD
22 GF Score
Price $4.60
! 6 Warning Signs
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What is Prelude Therapeutics Pre-Tax Income?

Prelude Therapeutics PRLD -8.91% 22 Pre-Tax Income is $-77.80 Mil as of Mar. 2026. GuruFocus rates PRLD with a GF Score™ of 22/100. The stock has 6 warning signs investors should review.

Pretax income is the income that a company earns before paying income taxes. Prelude Therapeutics's pretax income for the three months ended in Mar. 2026 was $-10.39 Mil. Its pretax income for the trailing twelve months (TTM) ended in Mar. 2026 was $-77.80 Mil. Prelude Therapeutics's pretax margin was -226.75%.

During the past 8 years, Prelude Therapeutics's highest Pretax Margin was -465.30%. The lowest was -1816.76%. And the median was -1318.18%.


Prelude Therapeutics  (NAS:PRLD) Pre-Tax Income Explanation

Prelude Therapeutics's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pretax Income/Revenue
=-10.385/4.58
=-226.75%

During the past 8 years, Prelude Therapeutics's highest Pretax Margin was -465.30%. The lowest was -1816.76%. And the median was -1318.18%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Prelude Therapeutics Pre-Tax Income Related Terms


Prelude Therapeutics Pre-Tax Income Historical Data

* Premium members only.

The historical data trend for Prelude Therapeutics's Pre-Tax Income can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Prelude Therapeutics Pre-Tax Income Chart

Prelude Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pre-Tax Income
Get a 7-Day Free Trial -111.69 -115.44 -121.83 -127.17 -99.50

Prelude Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pre-Tax Income Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -32.09 -31.23 -19.73 -16.46 -10.39

PRLD vs PROK, ZNTL, LYEL: Pre-Tax Income Comparison

For the Biotechnology subindustry, Prelude Therapeutics's Pre-Tax Income, along with its competitors' market caps and Pre-Tax Income data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Prelude Therapeutics Pre-Tax Income vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Prelude Therapeutics's Pre-Tax Income distribution charts can be found below:

* The bar in red indicates where Prelude Therapeutics's Pre-Tax Income falls into.


PRLD
22GF Score
Prelude Therapeutics Inc PRLD
Pre-Tax Income is just one metric. See GF Score™, valuation, warning signs, and more.
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Prelude Therapeutics Pre-Tax Income Calculation

This is the income that a company earns before paying income taxes.

Prelude Therapeutics's Pretax Income for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Income=Operating Income+Non Operating Income+Interest Expense+Interest Income+Other
=-104.566+5.068+0+0+0
=-99.50

Prelude Therapeutics's Pretax Income for the quarter that ended in Mar. 2026 is calculated as

Pretax Income=Operating Income+Non Operating Income+Interest Expense+Interest Income+Other
=-14.177+3.792+0+0+0
=-10.39

Pre-Tax Income for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-77.80 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pre-Tax Income →
What does a Pre-Tax Income of $-77.80 Mil mean?
Prelude Therapeutics (PRLD) has a Pre-Tax Income of $-77.80 Mil as of Mar. 2026. Pre-Tax Income is the total earnings before taxes but after all operating and interest expenses. View historical data on Prelude Therapeutics and its competitors.
Is Prelude Therapeutics' Pre-Tax Income too high?
Prelude Therapeutics' current Pre-Tax Income is $-77.80 Mil. Overall, Prelude Therapeutics has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does Prelude Therapeutics' Pre-Tax Income compare to PROK and ZNTL?
Prelude Therapeutics' Pre-Tax Income of $-77.80 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pre-Tax Income for a Biotechnology company?
A good Pre-Tax Income depends on the Biotechnology industry context. However, Pre-Tax Income should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pre-Tax Income mean?
A high Pre-Tax Income can signal that a stock is expensive relative to its fundamentals. Pre-Tax Income is the total earnings before taxes but after all operating and interest expenses. View historical data on Prelude Therapeutics and its competitors. Prelude Therapeutics's current Pre-Tax Income is $-77.80 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Prelude Therapeutics stock overvalued right now?
Prelude Therapeutics (PRLD) has a current Pre-Tax Income of $-77.80 Mil. The current Pre-Tax Income is $-77.80 Mil. Prelude Therapeutics' overall GF Score™ is 22/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pre-Tax Income calculated?
Pre-Tax Income is calculated from a company's financial statements. For Prelude Therapeutics (PRLD), the current Pre-Tax Income is $-77.80 Mil as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Prelude Therapeutics Business Description

Address 175 Innovation Boulevard, Wilmington, DE, USA, 19805
Prelude Therapeutics Incorp is a precision oncology company developing medicines in areas of high unmet need for cancer patients. Its pipeline features selective KAT6A degraders and mutant selective JAK2V617F JH2 inhibitors, new approaches to clinically validated targets with transformative potential for patients. The company is also leveraging its expertise in targeted protein degradation to discover and develop next-generation degrader antibody conjugates (DACs) with novel payloads.
22GF Score

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Pre-Tax Income is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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