PRLD (Prelude Therapeutics) OCF Yield %: -11.01 (As of Jul. 07, 2026)


PRLD Prelude Therapeutics Inc PRLD
26 GF Score
Price $4.99
! 6 Warning Signs
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What is Prelude Therapeutics OCF Yield %?

Prelude Therapeutics PRLD +1.63% 26 OCF Yield % is -11.01 as of Jul. 07, 2026. GuruFocus rates PRLD with a GF Score™ of 26/100. The stock has 6 warning signs investors should review. Among 1,410 Biotechnology companies, Prelude Therapeutics ranks worse than 56.95% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, Prelude Therapeutics's Trailing 12-Month Cash Flow from Operations is $-43.76 Mil, and Market Cap is $397.43 Mil. Therefore, Prelude Therapeutics's OCF Yield % for today is -11.01%.

The historical rank and industry rank for Prelude Therapeutics's OCF Yield % or its related term are showing as below:

PRLD' s OCF Yield % Range Over the Past 10 Years
Min: -205.36   Med: -108.89   Max: -10.79
Current: -11.01


During the past 8 years, the highest OCF Yield % of Prelude Therapeutics was -10.79%. The lowest was -205.36%. And the median was -108.89%.

PRLD's OCF Yield % is ranked worse than
56.95% of 1410 companies
in the Biotechnology industry
Industry Median: -7.975 vs PRLD: -11.01

Prelude Therapeutics's OCF Margin % for the quarter that ended in Mar. 2026 was %.


Prelude Therapeutics OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


Prelude Therapeutics OCF Yield % Related Terms


Prelude Therapeutics OCF Yield % Historical Data

* Premium members only.

The historical data trend for Prelude Therapeutics's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Prelude Therapeutics OCF Yield % Chart

Prelude Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial -14.09 -28.94 -45.66 -146.32 -30.84

Prelude Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -315.81 -227.69 -93.81 50.65 -40.25

PRLD vs DMAC, RCKT, CYDY: OCF Yield % Comparison

For the Biotechnology subindustry, Prelude Therapeutics's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Prelude Therapeutics OCF Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Prelude Therapeutics's OCF Yield % distribution charts can be found below:

* The bar in red indicates where Prelude Therapeutics's OCF Yield % falls into.


PRLD
26GF Score
Prelude Therapeutics Inc PRLD
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Prelude Therapeutics OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

Prelude Therapeutics's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=-56.302 / 182.5666
=-30.84%

Prelude Therapeutics's annualized OCF Yield % for the quarter that ended in Mar. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=-21.685 * 4 / 215.52156
=-40.25%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of -11.01 mean?
Prelude Therapeutics (PRLD) has a OCF Yield % of -11.01 as of Jul. 07, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Prelude Therapeutics and its competitors. According to the industry distribution chart, Prelude Therapeutics ranks #803 out of 1410 companies in the Biotechnology industry, placing it in the top 57%.
Is Prelude Therapeutics' OCF Yield % too high?
Prelude Therapeutics' current OCF Yield % is -11.01. Based on the distribution chart, Prelude Therapeutics ranks #803 out of 1410 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Prelude Therapeutics has a GF Score™ of 26/100, reflecting its overall financial health beyond just this single metric.
How does Prelude Therapeutics' OCF Yield % compare to DMAC and RCKT?
According to the Biotechnology industry distribution chart, Prelude Therapeutics ranks #803 out of 1410 companies for OCF Yield %. This places Prelude Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Biotechnology company?
A good OCF Yield % depends on the Biotechnology industry context. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Prelude Therapeutics and its competitors. Prelude Therapeutics's current OCF Yield % is -11.01. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Prelude Therapeutics stock overvalued right now?
Prelude Therapeutics (PRLD) has a current OCF Yield % of -11.01. The current OCF Yield % is -11.01. Prelude Therapeutics' overall GF Score™ is 26/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For Prelude Therapeutics (PRLD), the current OCF Yield % is -11.01 as of Jul. 07, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Prelude Therapeutics Business Description

Address 175 Innovation Boulevard, Wilmington, DE, USA, 19805
Prelude Therapeutics Incorp is a precision oncology company developing medicines in areas of high unmet need for cancer patients. Its pipeline features selective KAT6A degraders and mutant selective JAK2V617F JH2 inhibitors, new approaches to clinically validated targets with transformative potential for patients. The company is also leveraging its expertise in targeted protein degradation to discover and develop next-generation degrader antibody conjugates (DACs) with novel payloads.
26GF Score

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OCF Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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