Krystal Biotech (FRA:4KB) OCF Yield %: 2.28 (As of Jun. 27, 2026) — Near Median


FRA:4KB Krystal Biotech Inc FRA:4KB
58 GF Score
Price €313.40
GF Value €262.63
Valuation Modestly Overvalued
! 6 Warning Signs
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What is Krystal Biotech OCF Yield %?

Krystal Biotech FRA:4KB +3.23% 58 OCF Yield % is 2.28 as of Jun. 27, 2026, which is 1% below its 10-year median of 2.30. GuruFocus rates FRA:4KB with a GF Score™ of 58/100 and a GF Value™ of €262.63 (Modestly Overvalued). The stock has 6 warning signs investors should review. Among 1,419 Biotechnology companies, Krystal Biotech ranks better than 84.36% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, Krystal Biotech's Trailing 12-Month Cash Flow from Operations is €215.2 Mil, and Market Cap is €9,659.1 Mil. Therefore, Krystal Biotech's OCF Yield % for today is 2.28%.

The historical rank and industry rank for Krystal Biotech's OCF Yield % or its related term are showing as below:

FRA:4KB' s OCF Yield % Range Over the Past 10 Years
Min: -3.65   Med: 2.3   Max: 4.74
Current: 2.28


During the past 10 years, the highest OCF Yield % of Krystal Biotech was 4.74%. The lowest was -3.65%. And the median was 2.30%.

FRA:4KB's OCF Yield % is ranked better than
84.36% of 1419 companies
in the Biotechnology industry
Industry Median: -8.48 vs FRA:4KB: 2.28

Krystal Biotech's OCF Margin % for the quarter that ended in Mar. 2026 was %.


Krystal Biotech OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


Krystal Biotech OCF Yield % Related Terms


Krystal Biotech OCF Yield % Historical Data

* Premium members only.

The historical data trend for Krystal Biotech's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Krystal Biotech OCF Yield % Chart

Krystal Biotech Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2.71 -5.01 -2.51 2.70 2.74

Krystal Biotech Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.35 5.35 3.14 4.23 4.39

FRA:4KB vs NUVL, PRAX, TECH: OCF Yield % Comparison

For the Biotechnology subindustry, Krystal Biotech's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Krystal Biotech OCF Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Krystal Biotech's OCF Yield % distribution charts can be found below:

* The bar in red indicates where Krystal Biotech's OCF Yield % falls into.


FRA:4KB
58GF Score
Krystal Biotech Inc FRA:4KB
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Krystal Biotech OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

Krystal Biotech's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=171.539 / 6252.9264
=2.74%

Krystal Biotech's annualized OCF Yield % for the quarter that ended in Mar. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=69.53 * 4 / 6334.8424
=4.39%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of 2.28 mean?
Krystal Biotech (FRA:4KB) has a OCF Yield % of 2.28 as of Jun. 27, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Krystal Biotech and its competitors. This is near median its historical median of 2.30. According to the industry distribution chart, Krystal Biotech ranks #222 out of 1419 companies in the Biotechnology industry, placing it in the top 15.6%.
Is Krystal Biotech's OCF Yield % too high?
Krystal Biotech's current OCF Yield % of 2.28 is near median its 10-year median of 2.30. Based on the distribution chart, Krystal Biotech ranks #222 out of 1419 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Krystal Biotech has a GF Score™ of 58/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Krystal Biotech's OCF Yield % compare to NUVL and PRAX?
According to the Biotechnology industry distribution chart, Krystal Biotech ranks #222 out of 1419 companies for OCF Yield %. This places Krystal Biotech in the top 16% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Biotechnology company?
A good OCF Yield % depends on the Biotechnology industry context. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Krystal Biotech and its competitors. Krystal Biotech's current OCF Yield % is 2.28, which is near median its own 10-year median of 2.30. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Krystal Biotech stock overvalued right now?
Based on GuruFocus' analysis, Krystal Biotech (FRA:4KB) is currently considered Modestly Overvalued. The stock's GF Value™ is €262.63, compared to a current price of €313.40 — trading 19.3% above its estimated fair value. The current OCF Yield % is 2.28, which is near median its 10-year median of 2.30. Krystal Biotech's overall GF Score™ is 58/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For Krystal Biotech (FRA:4KB), the current OCF Yield % is 2.28 as of Jun. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Krystal Biotech (FRA:4KB) Overvalued in 2026?

Based on GuruFocus' analysis, Krystal Biotech stock appears to be overvalued. The current stock price of €313.40 is trading 19.3% above its estimated GF Value™ of €262.63. GuruFocus considers Krystal Biotech to be Modestly Overvalued.

Key valuation signals for FRA:4KB:

  • OCF Yield %: 2.28 (near median its 10-year median of 2.30)
  • GF Value™: €262.63 vs. price of €313.40 (19.3% above fair value)
  • GF Score™: 58/100 with 6 warning signs

No single metric tells the full story. See the FRA:4KB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Krystal Biotech Business Description

Address 2100 Wharton Street, Suite 701, Pittsburgh, PA, USA, 15203
Krystal Biotech Inc is an integrated, commercial-stage biotechnology company focused on the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs. The company uses its patented HSV-1-based gene therapy platform to create vectors that deliver therapeutic transgenes to target cells. It possesses exclusive rights to develop, manufacture, and commercialize VYJUVEK internationally. The company operates as one operating segment focused on pharmaceutical products and manufactures, markets, and sells VYJUVEK in the United States and markets and sells VYJUVEK in the European Union, and Japan.
58GF Score

Get the complete analysis for FRA:4KB

OCF Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€313.40
Price
€262.63
GF Value