Krystal Biotech (FRA:4KB) 3-Year RORE % : 38.52% (As of Mar. 2026)


FRA:4KB Krystal Biotech Inc FRA:4KB
58 GF Score
Price €327.20
GF Value €273.04
Valuation Modestly Overvalued
! 6 Warning Signs
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What is Krystal Biotech 3-Year RORE %?

Krystal Biotech FRA:4KB +0.89% 58 3-Year RORE % is 38.52 as of Mar. 2026. GuruFocus rates FRA:4KB with a GF Score™ of 58/100 and a GF Value™ of €273.04 (Modestly Overvalued). The stock has 6 warning signs investors should review. Among 1,290 Biotechnology companies, Krystal Biotech ranks better than 88.76% on this metric.

Return on Retained Earnings (RORE) is an indicator of a company's growth potential, it shows how much a company earns by reinvesting its retained earnings, i.e. profits after dividend payments. Krystal Biotech's 3-Year RORE % for the quarter that ended in Mar. 2026 was 38.52%.

The industry rank for Krystal Biotech's 3-Year RORE % or its related term are showing as below:

FRA:4KB's 3-Year RORE % is ranked better than
88.76% of 1290 companies
in the Biotechnology industry
Industry Median: -11.54 vs FRA:4KB: 38.52

Krystal Biotech  (FRA:4KB) 3-Year RORE % Explanation

Return on Retained Earnings (RORE) is important to investors because it reveals a company's efficiency and growth potential. A higher RORE indicates a higher return. A high RORE indicates that the company should reinvest profits into the business. A lower RORE suggests that the company should distribute profits to shareholders by paying out dividends, since those dollars aren't generating much additional growth for the company.

There are a several different ways to arrive at the Return on Retained Earnings. The simplest way to calculate it is by using published information on Earnings per Share (EPS) and Dividend per Share (DPS) over a selected period. Here, 3-year period is chosen.

Be Aware

Please keep in mind that the RORE is relative to the nature of the business and its competitors. If another company in the same sector is producing a lower return on retained earnings, it doesn’t necessarily mean it’s a bad investment. It may just suggest the company is older and no longer in a high growth stage. At such a stage in the business cycle, it would be expected to see a lower RORE and higher dividend payout.


Krystal Biotech 3-Year RORE % Related Terms


Krystal Biotech 3-Year RORE % Historical Data

* Premium members only.

The historical data trend for Krystal Biotech's 3-Year RORE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Krystal Biotech 3-Year RORE % Chart

Krystal Biotech Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year RORE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 30.28 40.11 -35.62 -345.21 66.15

Krystal Biotech Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year RORE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1,489.32 350.25 117.79 66.15 38.52

FRA:4KB vs TECH, SMMT, ARWR: 3-Year RORE % Comparison

For the Biotechnology subindustry, Krystal Biotech's 3-Year RORE %, along with its competitors' market caps and 3-Year RORE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Krystal Biotech 3-Year RORE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Krystal Biotech's 3-Year RORE % distribution charts can be found below:

* The bar in red indicates where Krystal Biotech's 3-Year RORE % falls into.


FRA:4KB
58GF Score
Krystal Biotech Inc FRA:4KB
3-Year RORE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Krystal Biotech 3-Year RORE % Calculation

Krystal Biotech's 3-Year RORE % for the quarter that ended in Mar. 2026 is calculated as:

3-Year RORE %=( Most Recent EPS (Diluted)- First Period EPS (Diluted) )/( Cumulative EPS (Diluted) for 3-year -Cumulative Dividends per Share for 3-year )
=( 6.419-1.772 )/( 12.065-0 )
=4.647/12.065
=38.52 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of 3-Year RORE %, the most recent and first period EPS (Diluted) is the trailing twelve months (TTM) data ended in Mar. 2026 and 3-year before.

Frequently Asked Questions Learn more about 3-Year RORE % →
What does a 3-Year RORE % of 38.52 mean?
Krystal Biotech (FRA:4KB) has a 3-Year RORE % of 38.52 as of Mar. 2026. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on Krystal Biotech and its competitors. According to the industry distribution chart, Krystal Biotech ranks #145 out of 1290 companies in the Biotechnology industry, placing it in the top 11.2%.
Is Krystal Biotech's 3-Year RORE % too high?
Krystal Biotech's current 3-Year RORE % is 38.52. Based on the distribution chart, Krystal Biotech ranks #145 out of 1290 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Krystal Biotech has a GF Score™ of 58/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Krystal Biotech's 3-Year RORE % compare to TECH and SMMT?
According to the Biotechnology industry distribution chart, Krystal Biotech ranks #145 out of 1290 companies for 3-Year RORE %. This places Krystal Biotech in the top 11% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year RORE % for a Biotechnology company?
A good 3-Year RORE % depends on the Biotechnology industry context. However, 3-Year RORE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year RORE % mean?
A high 3-Year RORE % can signal that a stock is expensive relative to its fundamentals. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on Krystal Biotech and its competitors. Krystal Biotech's current 3-Year RORE % is 38.52. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Krystal Biotech stock overvalued right now?
Based on GuruFocus' analysis, Krystal Biotech (FRA:4KB) is currently considered Modestly Overvalued. The stock's GF Value™ is €273.04, compared to a current price of €327.20 — trading 19.8% above its estimated fair value. The current 3-Year RORE % is 38.52. Krystal Biotech's overall GF Score™ is 58/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year RORE % calculated?
3-Year RORE % is calculated from a company's financial statements. For Krystal Biotech (FRA:4KB), the current 3-Year RORE % is 38.52 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Krystal Biotech (FRA:4KB) Overvalued in 2026?

Based on GuruFocus' analysis, Krystal Biotech stock appears to be overvalued. The current stock price of €327.20 is trading 19.8% above its estimated GF Value™ of €273.04. GuruFocus considers Krystal Biotech to be Modestly Overvalued.

Key valuation signals for FRA:4KB:

  • 3-Year RORE %: 38.52
  • GF Value™: €273.04 vs. price of €327.20 (19.8% above fair value)
  • GF Score™: 58/100 with 6 warning signs

No single metric tells the full story. See the FRA:4KB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Krystal Biotech Business Description

Address 2100 Wharton Street, Suite 701, Pittsburgh, PA, USA, 15203
Krystal Biotech Inc is an integrated, commercial-stage biotechnology company focused on the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs. The company uses its patented HSV-1-based gene therapy platform to create vectors that deliver therapeutic transgenes to target cells. It possesses exclusive rights to develop, manufacture, and commercialize VYJUVEK internationally. The company operates as one operating segment focused on pharmaceutical products and manufactures, markets, and sells VYJUVEK in the United States and markets and sells VYJUVEK in the European Union, and Japan.
58GF Score

Get the complete analysis for FRA:4KB

3-Year RORE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€327.20
Price
€273.04
GF Value