Tyra BiosciencesTYRA +3.07%28 PB Ratio is 4.89 as of Jun. 27, 2026. GuruFocus rates TYRA with a GF Score™ of 28/100. The stock has 2 warning signs investors should review. Among 1,232 Biotechnology companies, Tyra Biosciences ranks worse than 69.81% on this metric.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-06-27), Tyra Biosciences's share price is $31.88. Tyra Biosciences's Book Value per Share for the quarter that ended in Mar. 2026 was $6.52. Hence, Tyra Biosciences's PB Ratio of today is 4.89.
The historical rank and industry rank for Tyra Biosciences's PB Ratio or its related term are showing as below:
TYRA'
s PB Ratio Range Over the Past 10 Years
Min: 0 Med: 0 Max: 4.93
Current: 4.89
During the past 7 years, Tyra Biosciences's highest PB Ratio was 4.93. The lowest was 0.00. And the median was 0.00.
TYRA's PB Ratio is ranked worse than 69.81% of 1232
companies
in the Biotechnology industry
Industry Median: 2.8
vs TYRA: 4.89
During the past 12 months, Tyra Biosciences's average Book Value Per Share Growth Rate was -28.60% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -7.40% per year.
During the past 7 years, the highest 3-Year average Book Value Per Share Growth Rate of Tyra Biosciences was -2.40% per year. The lowest was -7.40% per year. And the median was -4.90% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
Tyra Biosciences PB Ratio Related Terms
Tyra Biosciences PB Ratio Historical Data
* Premium members only.
The historical data trend for Tyra Biosciences's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Tyra Biosciences's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Tyra Biosciences PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Tyra Biosciences's PB Ratio distribution charts can be found below:
* The bar in red indicates where Tyra Biosciences's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
Tyra Biosciences (TYRA) has a PB Ratio of 4.89 as of Jun. 27, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Tyra Biosciences and its competitors. According to the industry distribution chart, Tyra Biosciences ranks #860 out of 1232 companies in the Biotechnology industry, placing it in the top 69.8%.
Is Tyra Biosciences' PB Ratio too high?
Tyra Biosciences' current PB Ratio is 4.89. The Biotechnology industry median PB Ratio is 2.80. Tyra Biosciences' value of 4.89 is 74.6% above this industry median. Based on the distribution chart, Tyra Biosciences ranks #860 out of 1232 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Tyra Biosciences has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Tyra Biosciences' PB Ratio compare to ZLAB and OCUL?
According to the Biotechnology industry distribution chart, Tyra Biosciences ranks #860 out of 1232 companies for PB Ratio. This places Tyra Biosciences in the lower half of its industry. The industry median PB Ratio is 2.80. Tyra Biosciences' value of 4.89 is 74.6% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.80, based on 1,232 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Tyra Biosciences's current PB Ratio of 4.89 is 74.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Tyra Biosciences and its competitors. For the Biotechnology industry, the median PB Ratio is 2.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Tyra Biosciences's current PB Ratio is 4.89. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tyra Biosciences stock overvalued right now?
Tyra Biosciences (TYRA) has a current PB Ratio of 4.89. The current PB Ratio is 4.89 and 74.6% above the Biotechnology industry median of 2.80. Tyra Biosciences' overall GF Score™ is 28/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Tyra Biosciences (TYRA), the current PB Ratio is 4.89 as of Jun. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Tyra Biosciences Inc is a clinical-stage biotechnology company focused on developing next-generation precision medicines for large opportunities in targeted oncology and genetically defined conditions, harnessing the power of Fibroblast Growth Factor Receptor (FGFR) biology. The company's in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help to design and predict which product candidates may demonstrate the highest potency, selectivity, and tolerability in the clinic. The various drug candidates in the company's product pipeline are FGFR3, FGFR4/3, and FGFR1/2/3: three clinical-stage, novel small molecules designed to overcome the toxicity and resistance liabilities of first-generation pan-FGFR inhibitors.
28GF Score
Get the complete analysis for TYRA
PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
TYRA has been successfully added to your 
