XBIO (Xenetic Biosciences) Pretax Margin %: -56.51% (As of Mar. 2026)


XBIO Xenetic Biosciences Inc XBIO
79 GF Score
Price $2.77
GF Value $4.19
Valuation Possible Value Trap
! 2 Warning Signs
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What is Xenetic Biosciences Pretax Margin %?

Xenetic Biosciences XBIO -5.78% 79 Pretax Margin % is -56.51% as of Mar. 2026. GuruFocus rates XBIO with a GF Score™ of 79/100 and a GF Value™ of $4.19 (Possible Value Trap). The stock has 2 warning signs investors should review. Among 940 Biotechnology companies, Xenetic Biosciences ranks better than 52.13% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Xenetic Biosciences's Pre-Tax Income for the three months ended in Mar. 2026 was $-0.46 Mil. Xenetic Biosciences's Revenue for the three months ended in Mar. 2026 was $0.81 Mil. Therefore, Xenetic Biosciences's pretax margin for the quarter that ended in Mar. 2026 was -56.51%.

The historical rank and industry rank for Xenetic Biosciences's Pretax Margin % or its related term are showing as below:

XBIO' s Pretax Margin % Range Over the Past 10 Years
Min: -75147.06   Med: -383.83   Max: -47.4
Current: -70.03


XBIO's Pretax Margin % is ranked better than
52.13% of 940 companies
in the Biotechnology industry
Industry Median: -89.895 vs XBIO: -70.03

Xenetic Biosciences  (NAS:XBIO) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Xenetic Biosciences Pretax Margin % Related Terms


Xenetic Biosciences Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Xenetic Biosciences's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xenetic Biosciences Pretax Margin % Chart

Xenetic Biosciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -486.22 -383.83 -162.80 -158.40 -90.09

Xenetic Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -152.28 -116.78 -49.66 -75.59 -56.51

XBIO vs ACXP, SILO, GOVX: Pretax Margin % Comparison

For the Biotechnology subindustry, Xenetic Biosciences's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xenetic Biosciences Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Xenetic Biosciences's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Xenetic Biosciences's Pretax Margin % falls into.


XBIO
79GF Score
Xenetic Biosciences Inc XBIO
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Xenetic Biosciences Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Xenetic Biosciences's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-2.681/2.976
=-90.09 %

Xenetic Biosciences's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-0.456/0.807
=-56.51 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -56.51% mean?
Xenetic Biosciences (XBIO) has a Pretax Margin % of -56.51% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Xenetic Biosciences and its competitors. According to the industry distribution chart, Xenetic Biosciences ranks #450 out of 940 companies in the Biotechnology industry, placing it in the top 47.9%.
Is Xenetic Biosciences' Pretax Margin % too high?
Xenetic Biosciences' current Pretax Margin % is -56.51%. Based on the distribution chart, Xenetic Biosciences ranks #450 out of 940 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Xenetic Biosciences has a GF Score™ of 79/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Xenetic Biosciences' Pretax Margin % compare to ACXP and SILO?
According to the Biotechnology industry distribution chart, Xenetic Biosciences ranks #450 out of 940 companies for Pretax Margin %. This puts Xenetic Biosciences in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Xenetic Biosciences and its competitors. Xenetic Biosciences's current Pretax Margin % is -56.51%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xenetic Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Xenetic Biosciences (XBIO) is currently considered Possible Value Trap. The stock's GF Value™ is $4.19, compared to a current price of $2.77 — trading 33.9% below its estimated fair value. The current Pretax Margin % is -56.51%. Xenetic Biosciences' overall GF Score™ is 79/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Xenetic Biosciences (XBIO), the current Pretax Margin % is -56.51% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Xenetic Biosciences (XBIO) Overvalued in 2026?

Based on GuruFocus' analysis, Xenetic Biosciences stock appears to be undervalued. The current stock price of $2.77 is trading 33.9% below its estimated GF Value™ of $4.19. GuruFocus considers Xenetic Biosciences to be Possible Value Trap.

Key valuation signals for XBIO:

  • Pretax Margin %: -56.51%
  • GF Value™: $4.19 vs. price of $2.77 (33.9% below fair value)
  • GF Score™: 79/100 with 2 warning signs

No single metric tells the full story. See the XBIO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Xenetic Biosciences Business Description

Address 945 Concord Street, Framingham, MA, USA, 01701
Xenetic Biosciences Inc is a biopharmaceutical company focused on progressing XCART, a personalized CAR T platform technology engineered to target patient-specific tumor neoantigens. The Company is initially advancing cell-based therapeutics targeting the unique B-cell receptor on the surface of an individual patient’s malignant tumor cells for the treatment of B-cell lymphomas. XCART has the potential to fuel a robust pipeline of therapeutic assets targeting high-value oncology indications. Additionally, Xenetic is leveraging PolyXen™, its proprietary drug delivery platform, by partnering with biotechnology and pharmaceutical companies. PolyXen™ has demonstrated its ability to improve the half-life and other pharmacological properties of next-generation biologic drugs. The Company has an exclusive license agreement with Takeda Pharmaceuticals Co. Ltd. in the field of coagulation disorders and expects to earn royalty payments under this agreement.
79GF Score

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Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.77
Price
$4.19
GF Value