XBIO (Xenetic Biosciences) Return-on-Tangible-Asset: -50.01% (As of Jun. 2026)

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XBIO Xenetic Biosciences Inc XBIO
84 GF Score
Price $3.29
GF Value $3.75
Valuation Modestly Undervalued
! 2 Warning Signs
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What is Xenetic Biosciences Return-on-Tangible-Asset?

Xenetic Biosciences XBIO +0.61% 84 Return-on-Tangible-Asset is -50.01% as of Jun. 2026. GuruFocus rates XBIO with a GF Score™ of 84/100 and a GF Value™ of $3.75 (Modestly Undervalued). The stock has 2 warning signs investors should review. Among 1,414 Biotechnology companies, Xenetic Biosciences ranks worse than 50.14% on this metric.

Return-on-Tangible-Asset is calculated as Net Income divided by its average total tangible assets. Total tangible assets equals to Total Assets minus Intangible Assets. Xenetic Biosciences's annualized Net Income for the quarter that ended in Jun. 2026 was $-3.72 Mil. Xenetic Biosciences's average total tangible assets for the quarter that ended in Jun. 2026 was $7.44 Mil. Therefore, Xenetic Biosciences's annualized Return-on-Tangible-Asset for the quarter that ended in Jun. 2026 was -50.01%.

The historical rank and industry rank for Xenetic Biosciences's Return-on-Tangible-Asset or its related term are showing as below:

XBIO' s Return-on-Tangible-Asset Range Over the Past 10 Years
Min: -845.12   Med: -46.46   Max: -32.66
Current: -36.76

During the past 13 years, Xenetic Biosciences's highest Return-on-Tangible-Asset was -32.66%. The lowest was -845.12%. And the median was -46.46%.

XBIO's Return-on-Tangible-Asset is ranked worse than
50.14% of 1414 companies
in the Biotechnology industry
Industry Median: -36.16 vs XBIO: -36.76

Xenetic Biosciences  (NAS:XBIO) Return-on-Tangible-Asset Explanation

Return-on-Tangible-Asset measures the rate of return on the average total tangible assets (total assets minus intangible assets). Tangible means physical in nature. Intangible Assets are assets that are not physical in nature, and typically "derive their value from legal or intellectual rights." Return-on-Tangible-Asset measures a firm's efficiency at generating profits from its tangible assets. It shows how well a company uses what it has to generate earnings. Return-on-Tangible-Assets can vary drastically across industries. Therefore, Return-on-Tangible-Asset should not be used to compare companies in different industries.


Be Aware

Like ROE and ROA, Return-on-Tangible-Asset is calculated with only 12 months data. Fluctuations in the company’s earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. Return-on-Tangible-Asset can be affected by events such as stock buyback or issuance, and by a company’s tax rate and its interest payment. Return-on-Tangible-Asset may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high Return-on-Tangible-Asset may indicate vulnerability in the durability of the competitive advantage.


Xenetic Biosciences Return-on-Tangible-Asset Related Terms


Xenetic Biosciences Return-on-Tangible-Asset Historical Data

* Premium members only.

The historical data trend for Xenetic Biosciences's Return-on-Tangible-Asset can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xenetic Biosciences Return-on-Tangible-Asset Chart

Xenetic Biosciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Asset
Get a 7-Day Free Trial Premium Member Only Premium Member Only -34.22 -37.94 -32.66 -45.24 -35.13

Xenetic Biosciences Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Return-on-Tangible-Asset Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -49.46 -39.15 -34.48 -22.42 -50.01

XBIO vs ADIL, PULM, KAPA: Return-on-Tangible-Asset Comparison

For the Biotechnology subindustry, Xenetic Biosciences's Return-on-Tangible-Asset, along with its competitors' market caps and Return-on-Tangible-Asset data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xenetic Biosciences Return-on-Tangible-Asset vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Xenetic Biosciences's Return-on-Tangible-Asset distribution charts can be found below:

* The bar in red indicates where Xenetic Biosciences's Return-on-Tangible-Asset falls into.


XBIO
84GF Score
Xenetic Biosciences Inc XBIO
Return-on-Tangible-Asset is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Xenetic Biosciences Return-on-Tangible-Asset Calculation

Xenetic Biosciences's annualized Return-on-Tangible-Asset for the fiscal year that ended in Dec. 2025 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-2.681/( (6.901+8.364)/ 2 )
=-2.681/7.6325
=-35.13 %

Xenetic Biosciences's annualized Return-on-Tangible-Asset for the quarter that ended in Jun. 2026 is calculated as:

Return-on-Tangible-Asset=Net Income/( (Total Tangible Assets+Total Tangible Assets)/ count )
(Q: Jun. 2026 )  (Q: Mar. 2026 )(Q: Jun. 2026 )
=Net Income/( (Total Assets - Intangible Assets+Total Assets - Intangible Assets)/ count )
(Q: Jun. 2026 )  (Q: Mar. 2026 )(Q: Jun. 2026 )
=-3.72/( (7.909+6.968)/ 2 )
=-3.72/7.4385
=-50.01 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Asset, the net income of the last fiscal year and the average total tangible assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Jun. 2026) net income data.

What does a Return-on-Tangible-Asset of -50.01% mean?
Xenetic Biosciences (XBIO) has a Return-on-Tangible-Asset of -50.01% as of Jun. 2026. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Xenetic Biosciences and its competitors. According to the industry distribution chart, Xenetic Biosciences ranks #709 out of 1414 companies in the Biotechnology industry, placing it in the top 50.1%.
Is Xenetic Biosciences' Return-on-Tangible-Asset too high?
Xenetic Biosciences' current Return-on-Tangible-Asset is -50.01%. Based on the distribution chart, Xenetic Biosciences ranks #709 out of 1414 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Xenetic Biosciences has a GF Score™ of 84/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Xenetic Biosciences' Return-on-Tangible-Asset compare to ADIL and PULM?
According to the Biotechnology industry distribution chart, Xenetic Biosciences ranks #709 out of 1414 companies for Return-on-Tangible-Asset. This places Xenetic Biosciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Asset for a Biotechnology company?
A good Return-on-Tangible-Asset depends on the Biotechnology industry context. However, Return-on-Tangible-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Asset mean?
A high Return-on-Tangible-Asset can signal that a stock is expensive relative to its fundamentals. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on Xenetic Biosciences and its competitors. Xenetic Biosciences's current Return-on-Tangible-Asset is -50.01%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xenetic Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Xenetic Biosciences (XBIO) is currently considered Modestly Undervalued. The stock's GF Value™ is $3.75, compared to a current price of $3.29 — trading 12.3% below its estimated fair value. The current Return-on-Tangible-Asset is -50.01%. Xenetic Biosciences' overall GF Score™ is 84/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Asset calculated?
Return-on-Tangible-Asset is calculated from a company's financial statements. For Xenetic Biosciences (XBIO), the current Return-on-Tangible-Asset is -50.01% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Xenetic Biosciences (XBIO) Overvalued in 2026?

Based on GuruFocus' analysis, Xenetic Biosciences stock appears to be undervalued. The current stock price of $3.29 is trading 12.3% below its estimated GF Value™ of $3.75. GuruFocus considers Xenetic Biosciences to be Modestly Undervalued.

Key valuation signals for XBIO:

  • Return-on-Tangible-Asset: -50.01%
  • GF Value™: $3.75 vs. price of $3.29 (12.3% below fair value)
  • GF Score™: 84/100 with 2 warning signs

No single metric tells the full story. See the XBIO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Xenetic Biosciences Business Description

Address 945 Concord Street, Framingham, MA, USA, 01701
Xenetic Biosciences Inc is a biopharmaceutical company focused on progressing XCART, a personalized CAR T platform technology engineered to target patient-specific tumor neoantigens. The Company is initially advancing cell-based therapeutics targeting the unique B-cell receptor on the surface of an individual patient’s malignant tumor cells for the treatment of B-cell lymphomas. XCART has the potential to fuel a robust pipeline of therapeutic assets targeting high-value oncology indications. Additionally, Xenetic is leveraging PolyXen™, its proprietary drug delivery platform, by partnering with biotechnology and pharmaceutical companies. PolyXen™ has demonstrated its ability to improve the half-life and other pharmacological properties of next-generation biologic drugs. The Company has an exclusive license agreement with Takeda Pharmaceuticals Co. Ltd. in the field of coagulation disorders and expects to earn royalty payments under this agreement.
84GF Score

Get the complete analysis for XBIO

Return-on-Tangible-Asset is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$3.29
Price
$3.75
GF Value