DNLI (Denali Therapeutics) Retained Earnings: $-2,307.52 Mil (As of Jun. 2026)

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DNLI Denali Therapeutics Inc DNLI
33 GF Score
Price $25.69
! 6 Warning Signs
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What is Denali Therapeutics Retained Earnings?

Denali Therapeutics DNLI +5.63% 33 Retained Earnings is $-2,307.52 Mil as of Jun. 2026. GuruFocus rates DNLI with a GF Score™ of 33/100. The stock has 6 warning signs investors should review.

Retained earnings is the accumulated portion of net income that is not distributed to shareholders. Denali Therapeutics's retained earnings for the quarter that ended in Jun. 2026 was $-2,307.52 Mil.

Denali Therapeutics's quarterly retained earnings declined from Dec. 2025 ($-2,051.52 Mil) to Mar. 2026 ($-2,179.97 Mil) and declined from Mar. 2026 ($-2,179.97 Mil) to Jun. 2026 ($-2,307.52 Mil).

Denali Therapeutics's annual retained earnings declined from Dec. 2023 ($-1,116.21 Mil) to Dec. 2024 ($-1,538.98 Mil) and declined from Dec. 2024 ($-1,538.98 Mil) to Dec. 2025 ($-2,051.52 Mil).


Denali Therapeutics  (NAS:DNLI) Retained Earnings Explanation

Historically profitable companies sometimes have negative retained earnings. This is because they have cumulatively paid out more to shareholders than they reported in profits.

For example, in 2011, Microsoft had negative retained earnings. This does not mean the company lost more money than it made over the years. It just means it paid out more money than it earned.

If a company has negative retained earnings, investors should check the 10-year financial results. They should not assume that negative retained earnings prove a company has generally lost money in the past.

Of course, many companies with negative retained earnings have indeed lost money in the past.

Retained Earnings: Warren Buffett's Secret.

One of the most important indicators of durable competitive advantage. Net earnings can be paid out as dividends, used to buy back shares or retained for growth.

If the company loses more than it has accumulated, retained earnings is negative.

If a company isn't adding to its retained earnings, it isn't growing its net worth.

Rate of growth of retained earnings is good indicator whether it's benefiting from a competitive advantage.

Microsoft is negative because it chose to buyback stock and pay dividends.

The more earnings retained, the faster it grows and increases growth rate for future earnings.


Denali Therapeutics Retained Earnings Historical Data

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The historical data trend for Denali Therapeutics's Retained Earnings can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Denali Therapeutics Retained Earnings Chart

Denali Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Retained Earnings
Get a 7-Day Free Trial Premium Member Only Premium Member Only -645.00 -970.99 -1,116.21 -1,538.98 -2,051.52

Denali Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Retained Earnings Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1,796.07 -1,922.98 -2,051.52 -2,179.97 -2,307.52
DNLI
33GF Score
Denali Therapeutics Inc DNLI
Retained Earnings is just one metric. See GF Score™, valuation, warning signs, and more.
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Denali Therapeutics Retained Earnings Calculation

Retained Earnings is the accumulated portion of net income that is not distributed to shareholders. Because the net income was not distributed to shareholders, shareholders' equity is increased by the same amount.

Of course, if a company loses, it is called retained losses, or accumulated losses.

Frequently Asked Questions Learn more about Retained Earnings →
What does a Retained Earnings of $-2,307.52 Mil mean?
Denali Therapeutics (DNLI) has a Retained Earnings of $-2,307.52 Mil as of Jun. 2026. Retained earnings is the amount of net income not issued to shareholders. View historical data on Denali Therapeutics and its competitors.
Is Denali Therapeutics' Retained Earnings too high?
Denali Therapeutics' current Retained Earnings is $-2,307.52 Mil. Overall, Denali Therapeutics has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Denali Therapeutics' Retained Earnings compare to RCUS and ALMS?
Denali Therapeutics' Retained Earnings of $-2,307.52 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Retained Earnings for a Biotechnology company?
A good Retained Earnings depends on the Biotechnology industry context. However, Retained Earnings should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Retained Earnings mean?
A high Retained Earnings can signal that a stock is expensive relative to its fundamentals. Retained earnings is the amount of net income not issued to shareholders. View historical data on Denali Therapeutics and its competitors. Denali Therapeutics's current Retained Earnings is $-2,307.52 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Denali Therapeutics stock overvalued right now?
Denali Therapeutics (DNLI) has a current Retained Earnings of $-2,307.52 Mil. The current Retained Earnings is $-2,307.52 Mil. Denali Therapeutics' overall GF Score™ is 33/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Retained Earnings calculated?
Retained Earnings is calculated from a company's financial statements. For Denali Therapeutics (DNLI), the current Retained Earnings is $-2,307.52 Mil as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Denali Therapeutics Business Description

Other Exchanges 4DN:GermanyD2NL34:Brazil
Address 161 Oyster Point Boulevard, South San Francisco, CA, USA, 94080
Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegenerative diseases. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others. The Company has one operating segment with the goal to discover, develop, and commercializing therapeutics.
33GF Score

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Retained Earnings is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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