LYRA (Lyra Therapeutics) Retained Earnings: $-433.71 Mil (As of Dec. 2025)

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LYRA Lyra Therapeutics Inc LYRA
31 GF Score
Price $0.20
GF Value $2.46
Valuation Possible Value Trap
! 4 Warning Signs
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What is Lyra Therapeutics Retained Earnings?

Lyra Therapeutics LYRA +1,900.00% 31 Retained Earnings is $-433.71 Mil as of Dec. 2025. GuruFocus rates LYRA with a GF Score™ of 31/100 and a GF Value™ of $2.46 (Possible Value Trap). The stock has 4 warning signs investors should review.

Retained earnings is the accumulated portion of net income that is not distributed to shareholders. Lyra Therapeutics's retained earnings for the quarter that ended in Dec. 2025 was $-433.71 Mil.

Lyra Therapeutics's quarterly retained earnings declined from Jun. 2025 ($-420.77 Mil) to Sep. 2025 ($-426.76 Mil) and declined from Sep. 2025 ($-426.76 Mil) to Dec. 2025 ($-433.71 Mil).

Lyra Therapeutics's annual retained earnings declined from Dec. 2023 ($-311.36 Mil) to Dec. 2024 ($-404.79 Mil) and declined from Dec. 2024 ($-404.79 Mil) to Dec. 2025 ($-433.71 Mil).


Lyra Therapeutics  (OTCPK:LYRA) Retained Earnings Explanation

Historically profitable companies sometimes have negative retained earnings. This is because they have cumulatively paid out more to shareholders than they reported in profits.

For example, in 2011, Microsoft had negative retained earnings. This does not mean the company lost more money than it made over the years. It just means it paid out more money than it earned.

If a company has negative retained earnings, investors should check the 10-year financial results. They should not assume that negative retained earnings prove a company has generally lost money in the past.

Of course, many companies with negative retained earnings have indeed lost money in the past.

Retained Earnings: Warren Buffett's Secret.

One of the most important indicators of durable competitive advantage. Net earnings can be paid out as dividends, used to buy back shares or retained for growth.

If the company loses more than it has accumulated, retained earnings is negative.

If a company isn't adding to its retained earnings, it isn't growing its net worth.

Rate of growth of retained earnings is good indicator whether it's benefiting from a competitive advantage.

Microsoft is negative because it chose to buyback stock and pay dividends.

The more earnings retained, the faster it grows and increases growth rate for future earnings.


Lyra Therapeutics Retained Earnings Historical Data

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The historical data trend for Lyra Therapeutics's Retained Earnings can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lyra Therapeutics Retained Earnings Chart

Lyra Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Retained Earnings
Get a 7-Day Free Trial -193.40 -248.68 -311.36 -404.79 -433.71

Lyra Therapeutics Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Retained Earnings Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -404.79 -413.34 -420.77 -426.76 -433.71
LYRA
31GF Score
Lyra Therapeutics Inc LYRA
Retained Earnings is just one metric. See GF Score™, valuation, warning signs, and more.
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Lyra Therapeutics Retained Earnings Calculation

Retained Earnings is the accumulated portion of net income that is not distributed to shareholders. Because the net income was not distributed to shareholders, shareholders' equity is increased by the same amount.

Of course, if a company loses, it is called retained losses, or accumulated losses.

Frequently Asked Questions Learn more about Retained Earnings →
What does a Retained Earnings of $-433.71 Mil mean?
Lyra Therapeutics (LYRA) has a Retained Earnings of $-433.71 Mil as of Dec. 2025. Retained earnings is the amount of net income not issued to shareholders. View historical data on Lyra Therapeutics and its competitors.
Is Lyra Therapeutics' Retained Earnings too high?
Lyra Therapeutics' current Retained Earnings is $-433.71 Mil. Overall, Lyra Therapeutics has a GF Score™ of 31/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Lyra Therapeutics' Retained Earnings compare to RGBP and CYTOF?
Lyra Therapeutics' Retained Earnings of $-433.71 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Retained Earnings for a Biotechnology company?
A good Retained Earnings depends on the Biotechnology industry context. However, Retained Earnings should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Retained Earnings mean?
A high Retained Earnings can signal that a stock is expensive relative to its fundamentals. Retained earnings is the amount of net income not issued to shareholders. View historical data on Lyra Therapeutics and its competitors. Lyra Therapeutics's current Retained Earnings is $-433.71 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Lyra Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Lyra Therapeutics (LYRA) is currently considered Possible Value Trap. The stock's GF Value™ is $2.46, compared to a current price of $0.20 — trading 91.9% below its estimated fair value. The current Retained Earnings is $-433.71 Mil. Lyra Therapeutics' overall GF Score™ is 31/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Retained Earnings calculated?
Retained Earnings is calculated from a company's financial statements. For Lyra Therapeutics (LYRA), the current Retained Earnings is $-433.71 Mil as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Lyra Therapeutics (LYRA) Overvalued in 2026?

Based on GuruFocus' analysis, Lyra Therapeutics stock appears to be undervalued. The current stock price of $0.20 is trading 91.9% below its estimated GF Value™ of $2.46. GuruFocus considers Lyra Therapeutics to be Possible Value Trap.

Key valuation signals for LYRA:

  • Retained Earnings: $-433.71 Mil
  • GF Value™: $2.46 vs. price of $0.20 (91.9% below fair value)
  • GF Score™: 31/100 with 4 warning signs

No single metric tells the full story. See the LYRA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Lyra Therapeutics Business Description

Address 480 Arsenal Way, Watertown, MA, USA, 02472
Lyra Therapeutics Inc is a clinical-stage biotechnology company focused on the development and commercialization of anti-inflammatory therapies for the localized treatment of patients with chronic rhinosinusitis, or CRS. Its products include LYR-210 and LYR-220. The company operates in a single operating segment, which is the business of developing targeted medicines to address ear, nose, and throat, or ENT, diseases.
31GF Score

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Retained Earnings is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.20
Price
$2.46
GF Value