Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
XTL BiopharmaceuticalsXTLB +2.25%22 10-Year ROIIC % is -75.78 as of Dec. 2025. GuruFocus rates XTLB with a GF Score™ of 22/100. The stock has 4 warning signs investors should review. Among 1,107 Biotechnology companies, XTL Biopharmaceuticals ranks worse than 64.77% on this metric.
10-Year Return on Invested Incremental Capital (10-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 10-year.
XTL Biopharmaceuticals's 10-Year ROIIC % for the quarter that ended in Dec. 2025 was -75.78%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
The industry rank for XTL Biopharmaceuticals's 10-Year ROIIC % or its related term are showing as below:
XTLB's 10-Year ROIIC % is ranked worse than 64.77% of 1107
companies
in the Biotechnology industry
Industry Median: -19.8
vs XTLB: -75.78
Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.
High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
Be Aware
It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.
XTL Biopharmaceuticals 10-Year ROIIC % Related Terms
XTL Biopharmaceuticals 10-Year ROIIC % Historical Data
* Premium members only.
The historical data trend for XTL Biopharmaceuticals's 10-Year ROIIC % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
XTLB vs VRTX, REGN, ALNY: 10-Year ROIIC % Comparison
For the Biotechnology subindustry, XTL Biopharmaceuticals's 10-Year ROIIC %, along with its competitors' market caps and 10-Year ROIIC % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
XTL Biopharmaceuticals 10-Year ROIIC % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, XTL Biopharmaceuticals's 10-Year ROIIC % distribution charts can be found below:
* The bar in red indicates where XTL Biopharmaceuticals's 10-Year ROIIC % falls into.
XTL Biopharmaceuticals's 10-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:
10-Year ROIIC %
=
10-Year Incremental Net Operating Profit After Taxes (NOPAT)**
/
10-Year Incremental Invested Capital**
=
( -1.38 (Dec. 2025) - -2.007 (Dec. 2015) )
/
( 0.271 (Dec. 2025) - 1.098 (Dec. 2015) )
=
0.627
/
-0.827
=
-75.82%***
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** Annual data of NOPAT and Invested Capital was used to calculate 10-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
XTL Biopharmaceuticals (XTLB) has a 10-Year ROIIC % of -75.78 as of Dec. 2025. 10-Year ROIIC % measures the change in earnings as a percentage of change in investment over 10-year. View historical data on XTL Biopharmaceuticals and its competitors. According to the industry distribution chart, XTL Biopharmaceuticals ranks #717 out of 1107 companies in the Biotechnology industry, placing it in the top 64.8%.
Is XTL Biopharmaceuticals' 10-Year ROIIC % too high?
XTL Biopharmaceuticals' current 10-Year ROIIC % is -75.78. Based on the distribution chart, XTL Biopharmaceuticals ranks #717 out of 1107 companies in the Biotechnology industry, which is below the industry midpoint. Overall, XTL Biopharmaceuticals has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does XTL Biopharmaceuticals' 10-Year ROIIC % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, XTL Biopharmaceuticals ranks #717 out of 1107 companies for 10-Year ROIIC %. This places XTL Biopharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 10-Year ROIIC % for a Biotechnology company?
A good 10-Year ROIIC % depends on the Biotechnology industry context. However, 10-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 10-Year ROIIC % mean?
A high 10-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 10-Year ROIIC % measures the change in earnings as a percentage of change in investment over 10-year. View historical data on XTL Biopharmaceuticals and its competitors. XTL Biopharmaceuticals's current 10-Year ROIIC % is -75.78. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is XTL Biopharmaceuticals stock overvalued right now?
XTL Biopharmaceuticals (XTLB) has a current 10-Year ROIIC % of -75.78. The current 10-Year ROIIC % is -75.78. XTL Biopharmaceuticals' overall GF Score™ is 22/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 10-Year ROIIC % calculated?
10-Year ROIIC % is calculated from a company's financial statements. For XTL Biopharmaceuticals (XTLB), the current 10-Year ROIIC % is -75.78 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
XTL Biopharmaceuticals Ltd is engaged in the development of therapeutics for the treatment of unmet medical needs. Its products include hCDR1 and Recombinant Human Erythropoietin (rHuEPO). hCDR1 is a Phase II-ready asset compound, working through a mechanism of action, for the treatment of Systemic Lupus Erythematosus (SLE) and Sjogren's syndrome. hCDR1 is a synthetic peptide that includes approximately 20 amino-acid residues. rHuEPO, a known agent for anemia, is being developed to prolong the survival of patients with multiple myeloma (MM). rHuEPO is used in clinical practice for the treatment of various anemias, including anemia of kidney disease and cancer-related anemia.
22GF Score
Get the complete analysis for XTLB
10-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
XTLB has been successfully added to your 
