Clover Biopharmaceuticals (HKSE:02197) 3-Year ROIIC % : -335.03% (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

HKSE:02197 Clover Biopharmaceuticals Ltd HKSE:02197
28 GF Score
Price HK$1.91
! 3 Warning Signs
View Full Analysis

What is Clover Biopharmaceuticals 3-Year ROIIC %?

Clover Biopharmaceuticals HKSE:02197 -4.26% 28 3-Year ROIIC % is -335.03 as of Dec. 2025. GuruFocus rates HKSE:02197 with a GF Score™ of 28/100. The stock has 3 warning signs investors should review. Among 1,312 Biotechnology companies, Clover Biopharmaceuticals ranks worse than 85.59% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. Clover Biopharmaceuticals's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was -335.03%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Clover Biopharmaceuticals's 3-Year ROIIC % or its related term are showing as below:

HKSE:02197's 3-Year ROIIC % is ranked worse than
85.59% of 1312 companies
in the Biotechnology industry
Industry Median: -5.595 vs HKSE:02197: -335.03

Clover Biopharmaceuticals  (HKSE:02197) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Clover Biopharmaceuticals 3-Year ROIIC % Related Terms


Clover Biopharmaceuticals 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Clover Biopharmaceuticals's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Clover Biopharmaceuticals 3-Year ROIIC % Chart

Clover Biopharmaceuticals Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year ROIIC %
Get a 7-Day Free Trial 0.00 -84.20 -32.01 -1,181.63 -335.03

Clover Biopharmaceuticals Semi-Annual Data
Dec19 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only -32.01 0.00 -1,181.63 0.00 -335.03

HKSE:02197 vs VRTX, REGN, MRNA: 3-Year ROIIC % Comparison

For the Biotechnology subindustry, Clover Biopharmaceuticals's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Clover Biopharmaceuticals 3-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Clover Biopharmaceuticals's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Clover Biopharmaceuticals's 3-Year ROIIC % falls into.


HKSE:02197
28GF Score
Clover Biopharmaceuticals Ltd HKSE:02197
3-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Clover Biopharmaceuticals 3-Year ROIIC % Calculation

Clover Biopharmaceuticals's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( -239.798 (Dec. 2025) - -2078.376 (Dec. 2022) )/( 1883.912 (Dec. 2025) - 2432.694 (Dec. 2022) )
=1838.578/-548.782
=-335.03%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of -335.03 mean?
Clover Biopharmaceuticals (HKSE:02197) has a 3-Year ROIIC % of -335.03 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Clover Biopharmaceuticals and its competitors. According to the industry distribution chart, Clover Biopharmaceuticals ranks #1123 out of 1312 companies in the Biotechnology industry, placing it in the top 85.6%.
Is Clover Biopharmaceuticals' 3-Year ROIIC % too high?
Clover Biopharmaceuticals' current 3-Year ROIIC % is -335.03. Based on the distribution chart, Clover Biopharmaceuticals ranks #1123 out of 1312 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Clover Biopharmaceuticals has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Clover Biopharmaceuticals' 3-Year ROIIC % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Clover Biopharmaceuticals ranks #1123 out of 1312 companies for 3-Year ROIIC %. This places Clover Biopharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Clover Biopharmaceuticals and its competitors. Clover Biopharmaceuticals's current 3-Year ROIIC % is -335.03. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Clover Biopharmaceuticals stock overvalued right now?
Clover Biopharmaceuticals (HKSE:02197) has a current 3-Year ROIIC % of -335.03. The current 3-Year ROIIC % is -335.03. Clover Biopharmaceuticals' overall GF Score™ is 28/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Clover Biopharmaceuticals (HKSE:02197), the current 3-Year ROIIC % is -335.03 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Clover Biopharmaceuticals Business Description

Address No. 758 West Nanjing Road, Room 1901, Jing’an District, Shanghai, CHN
Clover Biopharmaceuticals Ltd is a clinical-stage biotechnology company committed to unleashing the power of vaccines to save lives and improve health around the world. The leverage the proprietary Trimer-Tag technology platform to conduct R&D for vaccines that can fulfill unmet needs, with a focus on building a respiratory vaccine franchise to reduce the burden of vaccine-preventable diseases. The Group has only one operating segment, which is the research and development, manufacturing, and commercialisation of vaccines. Geographically, the company earns revenue from Mainland China and Korea.
28GF Score

Get the complete analysis for HKSE:02197

3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

HK$1.91
Price