ANNX (Annexon) Cash-to-Debt: 8.49 (As of Jun. 2026) — Near Median

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ANNX Annexon Inc ANNX
34 GF Score
Price $3.92
! 2 Warning Signs
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What is Annexon Cash-to-Debt?

Annexon ANNX -5.06% 34 Cash-to-Debt is 8.49 as of Jun. 2026, which is 3% below its 10-year median of 8.73. GuruFocus rates ANNX with a GF Score™ of 34/100. The stock has 2 warning signs investors should review. Among 1,397 Biotechnology companies, Annexon ranks better than 52.9% on this metric.

Cash to Debt Ratio measures the financial strength of a company. It is calculated as a company's cash, cash equivalents, and marketable securities divide by its debt. Annexon's cash to debt ratio for the quarter that ended in Jun. 2026 was 8.49.

If Cash to Debt ratio is greater than 1, the company can pay off its debt using the cash in hand. Here we can see, Annexon could pay off its debt using the cash in hand for the quarter that ended in Jun. 2026.

The historical rank and industry rank for Annexon's Cash-to-Debt or its related term are showing as below:

ANNX' s Cash-to-Debt Range Over the Past 10 Years
Min: 5.2   Med: 8.73   Max: No Debt
Current: 8.49

During the past 8 years, Annexon's highest Cash to Debt Ratio was No Debt. The lowest was 5.20. And the median was 8.73.

ANNX's Cash-to-Debt is ranked better than
52.9% of 1397 companies
in the Biotechnology industry
Industry Median: 6.78 vs ANNX: 8.49

Annexon  (NAS:ANNX) Cash-to-Debt Explanation

If Cash to Debt ratio is greater than 1, the company can pay off its debt using the cash in hand. If it is smaller than 1, it means the company has more debt than the cash in hands. In this case, it is important to look the the company's Interest Coverage. Ben Graham requires that a company must have an Interest Coverage of at least 5.


Annexon Cash-to-Debt Related Terms


Annexon Cash-to-Debt Historical Data

* Premium members only.

The historical data trend for Annexon's Cash-to-Debt can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Note: An indication of "No Debt" does not necessarily mean that the company has no debt obligations; it could be due to missing data in the quarterly or annual report. Use caution when interpreting this information.

Annexon Cash-to-Debt Chart

Annexon Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cash-to-Debt
Get a 7-Day Free Trial 7.02 7.39 8.28 10.77 9.10

Annexon Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cash-to-Debt Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 8.22 7.01 9.10 8.85 8.49

ANNX vs DSGN, GERN, ARDX: Cash-to-Debt Comparison

For the Biotechnology subindustry, Annexon's Cash-to-Debt, along with its competitors' market caps and Cash-to-Debt data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Annexon Cash-to-Debt vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Annexon's Cash-to-Debt distribution charts can be found below:

* The bar in red indicates where Annexon's Cash-to-Debt falls into.


ANNX
34GF Score
Annexon Inc ANNX
Cash-to-Debt is just one metric. See GF Score™, valuation, warning signs, and more.
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Annexon Cash-to-Debt Calculation

This is the ratio of a company's Cash, Cash Equivalents, Marketable Securities to its debt. The debt includes the Short-Term Debt & Capital Lease Obligation and Long-Term Debt & Capital Lease Obligation. This ratio measures the financial strength of a company. This ratio is updated quarterly.

Annexon's Cash to Debt Ratio for the fiscal year that ended in Dec. 2025 is calculated as:

Annexon's Cash to Debt Ratio for the quarter that ended in Jun. 2026 is calculated as:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Cash-to-Debt →
What does a Cash-to-Debt of 8.49 mean?
Annexon (ANNX) has a Cash-to-Debt of 8.49 as of Jun. 2026. This is near median its historical median of 8.73. Over the past decade, Annexon's Cash-to-Debt has ranged from 5.20 to 10,000.00. According to the industry distribution chart, Annexon ranks #658 out of 1397 companies in the Biotechnology industry, placing it in the top 47.1%.
Is Annexon's Cash-to-Debt too high?
Annexon's current Cash-to-Debt of 8.49 is near median its 10-year median of 8.73. Over the past 10 years, this metric has ranged from a low of 5.20 to a high of 10,000.00. The Biotechnology industry median Cash-to-Debt is 6.78. Annexon's value of 8.49 is 25.2% above this industry median. Based on the distribution chart, Annexon ranks #658 out of 1397 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Annexon has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does Annexon's Cash-to-Debt compare to DSGN and GERN?
According to the Biotechnology industry distribution chart, Annexon ranks #658 out of 1397 companies for Cash-to-Debt. This puts Annexon in the upper half of its industry. The industry median Cash-to-Debt is 6.78. Annexon's value of 8.49 is 25.2% above this benchmark. Historically, Annexon's own Cash-to-Debt has ranged from 5.20 to 10,000.00 over the past decade. While the company's 10-year median is 8.73 vs. the industry median of 6.78, Annexon has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cash-to-Debt for a Biotechnology company?
The median Cash-to-Debt among Biotechnology companies is 6.78, based on 1,397 companies in the industry. Companies in the top quartile (top 25%) have a Cash-to-Debt significantly above this median, while those in the bottom quartile fall well below. However, Cash-to-Debt should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Annexon's current Cash-to-Debt of 8.49 is 25.2% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cash-to-Debt mean?
A high Cash-to-Debt can signal that a stock is expensive relative to its fundamentals. For the Biotechnology industry, the median Cash-to-Debt is 6.78 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Annexon's current Cash-to-Debt is 8.49, which is near median its own 10-year median of 8.73. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Annexon stock overvalued right now?
Annexon (ANNX) has a current Cash-to-Debt of 8.49. The current Cash-to-Debt is 8.49, which is near median its 10-year median of 8.73 and 25.2% above the Biotechnology industry median of 6.78. Annexon's overall GF Score™ is 34/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cash-to-Debt calculated?
Cash-to-Debt is calculated from a company's financial statements. For Annexon (ANNX), the current Cash-to-Debt is 8.49 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Annexon Business Description

Address 1400 Sierra Point Parkway, Suite 200, Building C, Brisbane, CA, USA, 94005
Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Its product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; ANX1502, for Oral small molecule; and ANX009, for systemic autoimmune diseases.
34GF Score

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