ANNX (Annexon) Earnings Yield (Joel Greenblatt) %: -29.24% (As of Mar. 2026)

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ANNX Annexon Inc ANNX
34 GF Score
Price $5.25
! 2 Warning Signs
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What is Annexon Earnings Yield (Joel Greenblatt) %?

Annexon ANNX +2.94% 34 Earnings Yield (Joel Greenblatt) % is -29.24% as of Mar. 2026. GuruFocus rates ANNX with a GF Score™ of 34/100. The stock has 2 warning signs investors should review. Among 1,319 Biotechnology companies, Annexon ranks worse than 72.1% on this metric.

Annexon's Enterprise Value for the quarter that ended in Mar. 2026 was $700.67 Mil. Annexon's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-205.06 Mil. Annexon's Earnings Yield (Joel Greenblatt) for the quarter that ended in Mar. 2026 was -29.24%.

The historical rank and industry rank for Annexon's Earnings Yield (Joel Greenblatt) % or its related term are showing as below:

ANNX' s Earnings Yield (Joel Greenblatt) % Range Over the Past 10 Years
Min: -33.44   Med: 0   Max: 0
Current: -31.06

ANNX's Earnings Yield (Joel Greenblatt) % is ranked worse than
72.1% of 1319 companies
in the Biotechnology industry
Industry Median: -10.07 vs ANNX: -31.06

Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.

A better indicator of the attractiveness of an investment which takes growth into account is the Forward Rate of Return (Yacktman) %. Annexon's Forward Rate of Return (Yacktman) % for the quarter that ended in Mar. 2026 was 0.00%. The Forward Rate of Return uses the normalized Free Cash Flow of the past five years, and considers growth. The forward rate of return can be thought of as the return that investors buying the stock today can expect from it in the future.


Annexon  (NAS:ANNX) Earnings Yield (Joel Greenblatt) % Explanation

Joel Greenblatt defines the earnings yield using the above equation because it more accurately reflects the company's profitability relative to its stock price. Items like interest payment and tax etc. are not directly related to the company's operational profitability.

Enterprise Value instead of market cap (share price) is used in the calculation because it is the real price stock and bond investors together pay for the company.


Be Aware

Joel Greenblatt's definition of earnings yield has the same problems the regular earnings yield does. It does not consider the growth of the company. It only looks at one-year's business operation. For cyclical companies, the earnings yield is usually highest at the peak of the business cycle. But these earnings are rarely sustainable.

Forward Rate of Return (Yacktman) % based on Don Yacktman's definition is a better measure of the expected rate of return for a stock.


Annexon Earnings Yield (Joel Greenblatt) % Related Terms


Annexon Earnings Yield (Joel Greenblatt) % Historical Data

* Premium members only.

The historical data trend for Annexon's Earnings Yield (Joel Greenblatt) % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Annexon Earnings Yield (Joel Greenblatt) % Chart

Annexon Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Earnings Yield (Joel Greenblatt) %
Get a 7-Day Free Trial -55.56 -400.00 -112.36 -55.56 -40.32

Annexon Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Earnings Yield (Joel Greenblatt) % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 769.23 -312.50 -114.94 -40.32 -29.24

ANNX vs ABUS, TBPH, SANA: Earnings Yield (Joel Greenblatt) % Comparison

For the Biotechnology subindustry, Annexon's Earnings Yield (Joel Greenblatt) %, along with its competitors' market caps and Earnings Yield (Joel Greenblatt) % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Annexon Earnings Yield (Joel Greenblatt) % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Annexon's Earnings Yield (Joel Greenblatt) % distribution charts can be found below:

* The bar in red indicates where Annexon's Earnings Yield (Joel Greenblatt) % falls into.


ANNX
34GF Score
Annexon Inc ANNX
Earnings Yield (Joel Greenblatt) % is just one metric. See GF Score™, valuation, warning signs, and more.
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Annexon Earnings Yield (Joel Greenblatt) % Calculation

In his book, The Little That Beat the Market, hedge fund manager Joel Greenblatt defines Earnings Yield as operating income divided by enterprise value.

Annexons Earnings Yield (Joel Greenblatt) for the fiscal year that ended in Dec. 2025 is calculated as

Earnings Yield (Joel Greenblatt)=EBIT/Enterprise Value
=-216.407/537.65826
=-40.25 %

Annexon's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-205.06 Mil.


What does a Earnings Yield (Joel Greenblatt) % of -29.24% mean?
Annexon (ANNX) has a Earnings Yield (Joel Greenblatt) % of -29.24% as of Mar. 2026. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Annexon and its competitors. According to the industry distribution chart, Annexon ranks #951 out of 1319 companies in the Biotechnology industry, placing it in the top 72.1%.
Is Annexon's Earnings Yield (Joel Greenblatt) % too high?
Annexon's current Earnings Yield (Joel Greenblatt) % is -29.24%. Based on the distribution chart, Annexon ranks #951 out of 1319 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Annexon has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does Annexon's Earnings Yield (Joel Greenblatt) % compare to ABUS and TBPH?
According to the Biotechnology industry distribution chart, Annexon ranks #951 out of 1319 companies for Earnings Yield (Joel Greenblatt) %. This places Annexon in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Earnings Yield (Joel Greenblatt) % for a Biotechnology company?
A good Earnings Yield (Joel Greenblatt) % depends on the Biotechnology industry context. However, Earnings Yield (Joel Greenblatt) % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Earnings Yield (Joel Greenblatt) % mean?
A high Earnings Yield (Joel Greenblatt) % can signal that a stock is expensive relative to its fundamentals. Joel Greenblatt's earnings yield equals the ratio of earnings before interest and taxes to enterprise value. View historical data on Annexon and its competitors. Annexon's current Earnings Yield (Joel Greenblatt) % is -29.24%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Annexon stock overvalued right now?
Annexon (ANNX) has a current Earnings Yield (Joel Greenblatt) % of -29.24%. The current Earnings Yield (Joel Greenblatt) % is -29.24%. Annexon's overall GF Score™ is 34/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Earnings Yield (Joel Greenblatt) % calculated?
Earnings Yield (Joel Greenblatt) % is calculated from a company's financial statements. For Annexon (ANNX), the current Earnings Yield (Joel Greenblatt) % is -29.24% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Annexon Business Description

Address 1400 Sierra Point Parkway, Suite 200, Building C, Brisbane, CA, USA, 94005
Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Its product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; ANX1502, for Oral small molecule; and ANX009, for systemic autoimmune diseases.
34GF Score

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Earnings Yield (Joel Greenblatt) % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.25
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