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AnnexonANNX +2.94%34 Earnings per Share (Diluted) is $-1.22 as of Mar. 2026. GuruFocus rates ANNX with a GF Score™ of 34/100. The stock has 2 warning signs investors should review. Among 1,166 Biotechnology companies, Annexon ranks better than 54.63% on this metric.
Annexon's EPS (Basic) for the
three
months ended in Mar. 2026 was $-0.23.
Its EPS (Basic) for the trailing twelve months (TTM) ended in Mar. 2026 was $-1.22.
Annexon's EPS without NRI for the
three
months ended in Mar. 2026 was $-0.23.
Its EPS without NRI for the trailing twelve months (TTM) ended in Mar. 2026 was $-1.22.
During the past 3 years, the average EPS without NRIGrowth Rate was 19.80% per year.
During the past 5 years, the average EPS without NRIGrowth Rate was 24.20% per year.
During the past 8 years, Annexon's highest 3-Year average EPS without NRI Growth Rate was 33.30% per year. The lowest was -28.20% per year. And the median was 19.80% per year.
Annexon (NAS:ANNX) Earnings per Share (Diluted) Explanation
Earnings Per Share (EPS) is the single most important variable used by Wall Street in determining the earnings power of a company. But investors need to be aware that Earnings per Share can be easily manipulated by adjusting depreciation and amortization rate or non-recurring items. That's why GuruFocus lists EPS without NRI, which better reflects the company's underlying performance.
Be Aware
Compared with Earnings per share, a company's cash flow is better indicator of the company's earnings power.
If a company's earnings per share is less than cash flow per share over long term, investors need to be cautious and find out why.
Annexon Earnings per Share (Diluted) Related Terms
Annexon Earnings per Share (Diluted) Historical Data
* Premium members only.
The historical data trend for Annexon's Earnings per Share (Diluted) can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ANNX vs ABUS, TBPH, SANA: Earnings per Share (Diluted) Comparison
For the Biotechnology subindustry, Annexon's PE Ratio, along with its competitors' market caps and PE Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Annexon PE Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Annexon's PE Ratio distribution charts can be found below:
* The bar in red indicates where Annexon's PE Ratio falls into.
Earnings Per Share (EPS) is the amount of earnings per outstanding share of the company's stock. In calculating earnings per share, the dividends of preferred stocks need to subtracted from the total net income first.
Annexon's Earnings Per Share (Diluted) for the fiscal year that ended in Dec. 2025 is calculated as
Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.22
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Companies also reported diluted shares in their financial reports. Diluted shares include the shares of convertibles or warrants outstanding.
What does a Earnings per Share (Diluted) of $-1.22 mean?
Annexon (ANNX) has a Earnings per Share (Diluted) of $-1.22 as of Mar. 2026. Diluted EPS equals net earnings divided by average shares outstanding, including dilutive securities. View historical data on Annexon and its competitors. According to the industry distribution chart, Annexon ranks #529 out of 1166 companies in the Biotechnology industry, placing it in the top 45.4%.
Is Annexon's Earnings per Share (Diluted) too high?
Annexon's current Earnings per Share (Diluted) is $-1.22. Based on the distribution chart, Annexon ranks #529 out of 1166 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Annexon has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does Annexon's Earnings per Share (Diluted) compare to ABUS and TBPH?
According to the Biotechnology industry distribution chart, Annexon ranks #529 out of 1166 companies for Earnings per Share (Diluted). This puts Annexon in the upper half of its industry. The industry median Earnings per Share (Diluted) is 16.20. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Earnings per Share (Diluted) for a Biotechnology company?
The median Earnings per Share (Diluted) among Biotechnology companies is 16.20, based on 1,166 companies in the industry. Companies in the top quartile (top 25%) have a Earnings per Share (Diluted) significantly above this median, while those in the bottom quartile fall well below. However, Earnings per Share (Diluted) should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Earnings per Share (Diluted) mean?
A high Earnings per Share (Diluted) can signal that a stock is expensive relative to its fundamentals. Diluted EPS equals net earnings divided by average shares outstanding, including dilutive securities. View historical data on Annexon and its competitors. For the Biotechnology industry, the median Earnings per Share (Diluted) is 16.20 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Annexon's current Earnings per Share (Diluted) is $-1.22. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Annexon stock overvalued right now?
Annexon (ANNX) has a current Earnings per Share (Diluted) of $-1.22. The current Earnings per Share (Diluted) is $-1.22. Annexon's overall GF Score™ is 34/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Earnings per Share (Diluted) calculated?
Earnings per Share (Diluted) is calculated from a company's financial statements. For Annexon (ANNX), the current Earnings per Share (Diluted) is $-1.22 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Its product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; ANX1502, for Oral small molecule; and ANX009, for systemic autoimmune diseases.
34GF Score
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