OPKO Health (LTS:0KCS) Cyclically Adjusted PB Ratio: (As of Jul. 28, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
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Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

LTS:0KCS OPKO Health Inc LTS:0KCS
58 GF Score
Price $1.22
GF Value $1.06
Valuation Modestly Overvalued
! 4 Warning Signs
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What is OPKO Health Cyclically Adjusted PB Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


OPKO Health  (LTS:0KCS) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


OPKO Health Cyclically Adjusted PB Ratio Related Terms


OPKO Health Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for OPKO Health's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OPKO Health Cyclically Adjusted PB Ratio Chart

OPKO Health Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 1.71 0.40 0.47 0.45 0.40

OPKO Health Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.40 0.48 0.40 0.36 0.00

LTS:0KCS vs CSTL, FRNM, PSNL: Cyclically Adjusted PB Ratio Comparison

For the Diagnostics & Research subindustry, OPKO Health's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OPKO Health Cyclically Adjusted PB Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, OPKO Health's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where OPKO Health's Cyclically Adjusted PB Ratio falls into.


LTS:0KCS
58GF Score
OPKO Health Inc LTS:0KCS
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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OPKO Health Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

OPKO Health's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, OPKO Health's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=1.568/333.9520*333.9520
=1.568

Current CPI (Jun. 2026) = 333.9520.

OPKO Health Quarterly Data

Book Value per Share CPI Adj_Book
201609 3.777 241.428 5.224
201612 3.749 241.432 5.186
201703 3.769 243.801 5.163
201706 3.766 244.955 5.134
201709 3.734 246.819 5.052
201712 3.295 246.524 4.464
201803 3.259 249.554 4.361
201806 3.235 251.989 4.287
201809 3.195 252.439 4.227
201812 3.055 251.233 4.061
201903 2.863 254.202 3.761
201906 2.776 256.143 3.619
201909 2.667 256.759 3.469
201912 2.411 256.974 3.133
202003 2.312 258.115 2.991
202006 2.371 257.797 3.071
202009 2.424 260.280 3.110
202012 2.493 260.474 3.196
202103 2.532 264.877 3.192
202106 2.558 271.696 3.144
202109 2.591 274.310 3.154
202112 2.473 278.802 2.962
202203 2.370 287.504 2.753
202206 2.227 296.311 2.510
202209 2.108 296.808 2.372
202212 2.021 296.797 2.274
202303 2.008 301.836 2.222
202306 1.986 305.109 2.174
202309 1.869 307.789 2.028
202312 1.797 306.746 1.956
202403 1.797 312.332 1.921
202406 2.001 314.175 2.127
202409 2.056 315.301 2.178
202412 2.033 315.605 2.151
202503 1.953 319.799 2.039
202506 1.663 322.561 1.722
202509 1.698 324.800 1.746
202512 1.670 324.054 1.721
202603 1.595 330.213 1.613
202606 1.568 333.952 1.568

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is OPKO Health (LTS:0KCS) Overvalued in 2026?

Based on GuruFocus' analysis, OPKO Health stock appears to be overvalued. The current stock price of $1.22 is trading 15.1% above its estimated GF Value™ of $1.06. GuruFocus considers OPKO Health to be Modestly Overvalued.

Key valuation signals for LTS:0KCS:

  • Cyclically Adjusted PB Ratio:
  • GF Value™: $1.06 vs. price of $1.22 (15.1% above fair value)
  • GF Score™: 58/100 with 4 warning signs

No single metric tells the full story. See the LTS:0KCS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OPKO Health Business Description

Address 4400 Biscayne Boulevard, Miami, FL, USA, 33137
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
58GF Score

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Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.22
Price
$1.06
GF Value