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OPKO HealthLTS:0KCS +0.36%57 EV-to-OCF is -9.23 as of Aug. 13, 2026. GuruFocus rates LTS:0KCS with a GF Score™ of 57/100 and a GF Value™ of $1.12 (Modestly Overvalued). The stock has 6 warning signs investors should review. Among 213 Medical Diagnostics & Research companies, OPKO Health ranks better than 77.93% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, OPKO Health's Enterprise Value is $1,138.5 Mil.
OPKO Health's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was $-123.4 Mil. Therefore, OPKO Health's EV-to-OCF for today is -9.23.
The historical rank and industry rank for OPKO Health's EV-to-OCF or its related term are showing as below:
LTS:0KCS'
s EV-to-OCF Range Over the Past 10 Years
Min: -863.94 Med: -12.96 Max: 605.45
Current: -9.23
During the past 13 years, the highest EV-to-OCF of OPKO Health was 605.45. The lowest was -863.94. And the median was -12.96.
LTS:0KCS's EV-to-OCF is ranked better than 77.93% of 213
companies
in the Medical Diagnostics & Research industry
Industry Median: 6.2
vs LTS:0KCS: -9.23
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
OPKO Health's PE Ratio (TTM) for today is calculated as:
OPKO Health's share price for today is $1.40.
OPKO Health's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.090.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
OPKO Health EV-to-OCF Related Terms
OPKO Health EV-to-OCF Historical Data
* Premium members only.
The historical data trend for OPKO Health's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
LTS:0KCS vs CSTL, FRNM, PSNL: EV-to-OCF Comparison
For the Diagnostics & Research subindustry, OPKO Health's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
OPKO Health EV-to-OCF vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, OPKO Health's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where OPKO Health's EV-to-OCF falls into.
OPKO Health's current Enterprise Value is $1,138.5 Mil.
OPKO Health's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-123.4 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
OPKO Health (LTS:0KCS) has a EV-to-OCF of -9.23 as of Aug. 13, 2026. According to the industry distribution chart, OPKO Health ranks #47 out of 213 companies in the Medical Diagnostics & Research industry, placing it in the top 22.1%.
Is OPKO Health's EV-to-OCF too high?
OPKO Health's current EV-to-OCF is -9.23. Based on the distribution chart, OPKO Health ranks #47 out of 213 companies in the Medical Diagnostics & Research industry, which is in the top quartile — a strong position relative to peers. Overall, OPKO Health has a GF Score™ of 57/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OPKO Health's EV-to-OCF compare to CSTL and FRNM?
According to the Medical Diagnostics & Research industry distribution chart, OPKO Health ranks #47 out of 213 companies for EV-to-OCF. This places OPKO Health in the top 22% of its industry — outperforming the majority of peers. The industry median EV-to-OCF is 6.20. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Medical Diagnostics & Research company?
The median EV-to-OCF among Medical Diagnostics & Research companies is 6.20, based on 213 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-OCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. For the Medical Diagnostics & Research industry, the median EV-to-OCF is 6.20 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OPKO Health's current EV-to-OCF is -9.23. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OPKO Health stock overvalued right now?
Based on GuruFocus' analysis, OPKO Health (LTS:0KCS) is currently considered Modestly Overvalued. The stock's GF Value™ is $1.12, compared to a current price of $1.40 — trading 25% above its estimated fair value. The current EV-to-OCF is -9.23. OPKO Health's overall GF Score™ is 57/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For OPKO Health (LTS:0KCS), the current EV-to-OCF is -9.23 as of Aug. 13, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is OPKO Health (LTS:0KCS) Overvalued in 2026?
Based on GuruFocus' analysis, OPKO Health stock appears to be overvalued.
The current stock price of $1.40 is trading 25% above its estimated GF Value™ of $1.12.
GuruFocus considers OPKO Health to be Modestly Overvalued.
Key valuation signals for LTS:0KCS:
EV-to-OCF: -9.23
GF Value™: $1.12 vs. price of $1.40 (25% above fair value)
No single metric tells the full story. See the LTS:0KCS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
57GF Score
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