Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
OPKO HealthLTS:0KCS -0.61%48 Degree of Operating Leverage is 0.06 as of Jun. 2026. GuruFocus rates LTS:0KCS with a GF Score™ of 48/100 and a GF Value™ of $1.16 (Significantly Overvalued). The stock has 8 warning signs investors should review. Among 197 Medical Diagnostics & Research companies, OPKO Health ranks better than 57.36% on this metric.
Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue.
OPKO Health's Degree of Operating Leverage for the quarter that ended in Jun. 2026 was 0.06. The higher Degree of Operating Leverage, the higher operating risk the company will take.
The industry rank for OPKO Health's Degree of Operating Leverage or its related term are showing as below:
LTS:0KCS's Degree of Operating Leverage is ranked better than 57.36% of 197
companies
in the Medical Diagnostics & Research industry
Industry Median: 0.44
vs LTS:0KCS: 0.06
OPKO Health (LTS:0KCS) Degree of Operating Leverage Explanation
Degree of Operating Leverage (DOL) is a leverage ratio that measures the sensitivity of a company’s operting income, also referred to as Earnings Before Interest and Taxes (EBIT), to fluctuations in its Revenue. DOL is a method used to quantify a company’s operating risk. This risk is related to the company's structure of variable costs and fixed costs. Since the fixed costs do not allow the company to adjust the operating costs, the operating risk rises with a higher fixed-to-variable costs proportion.
A high Degree of Operating Leverage indicates that the company’s fixed costs exceed its variable costs. By increasing the sales, the company can earn more profits. In addition, the company must be able to maintain relatively high sales to cover all fixed costs.
Be Aware
The use of operating leverage varies across different industries and business sectors, and the application of Degree of Operating Leverage (DOL) should be adjusted accordingly.
OPKO Health Degree of Operating Leverage Related Terms
OPKO Health Degree of Operating Leverage Historical Data
* Premium members only.
The historical data trend for OPKO Health's Degree of Operating Leverage can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
LTS:0KCS vs CSTL, FRNM, FLGT: Degree of Operating Leverage Comparison
For the Diagnostics & Research subindustry, OPKO Health's Degree of Operating Leverage, along with its competitors' market caps and Degree of Operating Leverage data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
OPKO Health Degree of Operating Leverage vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, OPKO Health's Degree of Operating Leverage distribution charts can be found below:
* The bar in red indicates where OPKO Health's Degree of Operating Leverage falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** TTM data of EBIT and Revenue was used to calculate Degree of Operating Leverage.
*** Please be aware that the Degree of Operating Leverage calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
What does a Degree of Operating Leverage of 0.06 mean?
OPKO Health (LTS:0KCS) has a Degree of Operating Leverage of 0.06 as of Jun. 2026. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for OPKO Health and its competitors. According to the industry distribution chart, OPKO Health ranks #84 out of 197 companies in the Medical Diagnostics & Research industry, placing it in the top 42.6%.
Is OPKO Health's Degree of Operating Leverage too high?
OPKO Health's current Degree of Operating Leverage is 0.06. The Medical Diagnostics & Research industry median Degree of Operating Leverage is 0.44. OPKO Health's value of 0.06 is 86.4% below this industry median. Based on the distribution chart, OPKO Health ranks #84 out of 197 companies in the Medical Diagnostics & Research industry, which is above the industry midpoint. Overall, OPKO Health has a GF Score™ of 48/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OPKO Health's Degree of Operating Leverage compare to CSTL and FRNM?
According to the Medical Diagnostics & Research industry distribution chart, OPKO Health ranks #84 out of 197 companies for Degree of Operating Leverage. This puts OPKO Health in the upper half of its industry. The industry median Degree of Operating Leverage is 0.44. OPKO Health's value of 0.06 is 86.4% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Degree of Operating Leverage for a Medical Diagnostics & Research company?
The median Degree of Operating Leverage among Medical Diagnostics & Research companies is 0.44, based on 197 companies in the industry. Companies in the top quartile (top 25%) have a Degree of Operating Leverage significantly above this median, while those in the bottom quartile fall well below. However, Degree of Operating Leverage should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. OPKO Health's current Degree of Operating Leverage of 0.06 is 86.4% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Degree of Operating Leverage mean?
A high Degree of Operating Leverage can signal that a stock is expensive relative to its fundamentals. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for OPKO Health and its competitors. For the Medical Diagnostics & Research industry, the median Degree of Operating Leverage is 0.44 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OPKO Health's current Degree of Operating Leverage is 0.06. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OPKO Health stock overvalued right now?
Based on GuruFocus' analysis, OPKO Health (LTS:0KCS) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.16, compared to a current price of $1.63 — trading 40.5% above its estimated fair value. The current Degree of Operating Leverage is 0.06 and 86.4% below the Medical Diagnostics & Research industry median of 0.44. OPKO Health's overall GF Score™ is 48/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Degree of Operating Leverage calculated?
Degree of Operating Leverage is calculated from a company's financial statements. For OPKO Health (LTS:0KCS), the current Degree of Operating Leverage is 0.06 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is OPKO Health (LTS:0KCS) Overvalued in 2026?
Based on GuruFocus' analysis, OPKO Health stock appears to be overvalued.
The current stock price of $1.63 is trading 40.5% above its estimated GF Value™ of $1.16.
GuruFocus considers OPKO Health to be Significantly Overvalued.
Key valuation signals for LTS:0KCS:
Degree of Operating Leverage: 0.06
GF Value™: $1.16 vs. price of $1.63 (40.5% above fair value)
Industry Position: 86.4% below the Medical Diagnostics & Research median (#84 of 197)
No single metric tells the full story. See the LTS:0KCS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
48GF Score
Get the complete analysis for LTS:0KCS
Degree of Operating Leverage is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
LTS:0KCS has been successfully added to your 
