OPKO Health (LTS:0KCS) Gross Profit: $239.7 Mil (TTM As of Jun. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

LTS:0KCS OPKO Health Inc LTS:0KCS
58 GF Score
Price $1.33
GF Value $1.13
Valuation Modestly Overvalued
! 5 Warning Signs
View Full Analysis

What is OPKO Health Gross Profit?

OPKO Health LTS:0KCS +1.14% 58 Gross Profit is $239.7 Mil as of Jun. 2026. GuruFocus rates LTS:0KCS with a GF Score™ of 58/100 and a GF Value™ of $1.13 (Modestly Overvalued). The stock has 5 warning signs investors should review.

OPKO Health's gross profit for the three months ended in Jun. 2026 was $80.0 Mil. OPKO Health's gross profit for the trailing twelve months (TTM) ended in Jun. 2026 was $239.7 Mil.

Gross Margin % is calculated as gross profit divided by its revenue. OPKO Health's gross profit for the three months ended in Jun. 2026 was $80.0 Mil. OPKO Health's Revenue for the three months ended in Jun. 2026 was $163.6 Mil. Therefore, OPKO Health's Gross Margin % for the quarter that ended in Jun. 2026 was 48.92%.

OPKO Health had a gross margin of 48.92% for the quarter that ended in Jun. 2026 => Durable competitive advantage

During the past 13 years, the highest Gross Margin % of OPKO Health was 45.28%. The lowest was 28.70%. And the median was 36.17%.

Warning Sign:

OPKO Health Inc gross margin has been in long-term decline. The average rate of decline per year is -1.4%.


OPKO Health  (LTS:0KCS) Gross Profit Explanation

Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.

Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %

1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key

OPKO Health had a gross margin of 48.92% for the quarter that ended in Jun. 2026 => Durable competitive advantage


OPKO Health Gross Profit Related Terms


OPKO Health Gross Profit Historical Data

* Premium members only.

The historical data trend for OPKO Health's Gross Profit can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OPKO Health Gross Profit Chart

OPKO Health Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Gross Profit
Get a 7-Day Free Trial Premium Member Only Premium Member Only 581.52 288.22 318.13 218.51 205.94

OPKO Health Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Gross Profit Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 49.40 49.89 64.03 45.76 80.02

LTS:0KCS vs CSTL, FRNM, PSNL: Gross Profit Comparison

For the Diagnostics & Research subindustry, OPKO Health's Gross Profit, along with its competitors' market caps and Gross Profit data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OPKO Health Gross Profit vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, OPKO Health's Gross Profit distribution charts can be found below:

* The bar in red indicates where OPKO Health's Gross Profit falls into.


LTS:0KCS
58GF Score
OPKO Health Inc LTS:0KCS
Gross Profit is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

OPKO Health Gross Profit Calculation

Gross Profit is the different between the sale prices and the cost of buying or producing the goods.

OPKO Health's Gross Profit for the fiscal year that ended in Dec. 2025 is calculated as

Gross Profit (A: Dec. 2025 )=Revenue - Cost of Goods Sold
=606.879 - 400.939
=205.9

OPKO Health's Gross Profit for the quarter that ended in Jun. 2026 is calculated as

Gross Profit (Q: Jun. 2026 )=Revenue - Cost of Goods Sold
=163.58 - 83.563
=80.0

Gross Profit for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $239.7 Mil.

Gross Profit is the numerator in the calculation of Gross Margin.

OPKO Health's Gross Margin % for the quarter that ended in Jun. 2026 is calculated as

Gross Margin % (Q: Jun. 2026 )=Gross Profit (Q: Jun. 2026 ) / Revenue (Q: Jun. 2026 )
=(Revenue - Cost of Goods Sold) / Revenue
=80.0 / 163.58
=48.92 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.

Frequently Asked Questions Learn more about Gross Profit →
What does a Gross Profit of $239.7 Mil mean?
OPKO Health (LTS:0KCS) has a Gross Profit of $239.7 Mil as of Jun. 2026. Gross Profit equals net sales less total cost of goods sold. View historical data on OPKO Health and its competitors.
Is OPKO Health's Gross Profit too high?
OPKO Health's current Gross Profit is $239.7 Mil. Overall, OPKO Health has a GF Score™ of 58/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OPKO Health's Gross Profit compare to CSTL and FRNM?
OPKO Health's Gross Profit of $239.7 Mil can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Gross Profit for a Medical Diagnostics & Research company?
A good Gross Profit depends on the Medical Diagnostics & Research industry context. However, Gross Profit should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Gross Profit mean?
A high Gross Profit can signal that a stock is expensive relative to its fundamentals. Gross Profit equals net sales less total cost of goods sold. View historical data on OPKO Health and its competitors. OPKO Health's current Gross Profit is $239.7 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OPKO Health stock overvalued right now?
Based on GuruFocus' analysis, OPKO Health (LTS:0KCS) is currently considered Modestly Overvalued. The stock's GF Value™ is $1.13, compared to a current price of $1.33 — trading 17.7% above its estimated fair value. The current Gross Profit is $239.7 Mil. OPKO Health's overall GF Score™ is 58/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Gross Profit calculated?
Gross Profit is calculated from a company's financial statements. For OPKO Health (LTS:0KCS), the current Gross Profit is $239.7 Mil as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OPKO Health (LTS:0KCS) Overvalued in 2026?

Based on GuruFocus' analysis, OPKO Health stock appears to be overvalued. The current stock price of $1.33 is trading 17.7% above its estimated GF Value™ of $1.13. GuruFocus considers OPKO Health to be Modestly Overvalued.

Key valuation signals for LTS:0KCS:

  • Gross Profit: $239.7 Mil
  • GF Value™: $1.13 vs. price of $1.33 (17.7% above fair value)
  • GF Score™: 58/100 with 5 warning signs

No single metric tells the full story. See the LTS:0KCS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OPKO Health Business Description

Address 4400 Biscayne Boulevard, Miami, FL, USA, 33137
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
58GF Score

Get the complete analysis for LTS:0KCS

Gross Profit is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.33
Price
$1.13
GF Value