KPTI (Karyopharm Therapeutics) 5-Year EBITDA Growth Rate: 23.80% (As of Jun. 2026)

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KPTI Karyopharm Therapeutics Inc KPTI
45 GF Score
Price $1.68
GF Value $4.58
Valuation Possible Value Trap
! 6 Warning Signs
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What is Karyopharm Therapeutics 5-Year EBITDA Growth Rate?

Karyopharm Therapeutics KPTI -3.17% 45 5-Year EBITDA Growth Rate is 23.80% as of Jun. 2026. GuruFocus rates KPTI with a GF Score™ of 45/100 and a GF Value™ of $4.58 (Possible Value Trap). The stock has 6 warning signs investors should review.

Karyopharm Therapeutics's EBITDA per Share for the three months ended in Jun. 2026 was $-1.86.

During the past 3 years, the average EBITDA Per Share Growth Rate was 18.70% per year. During the past 5 years, the average EBITDA Per Share Growth Rate was 23.80% per year. During the past 10 years, the average EBITDA Per Share Growth Rate was 17.00% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average EBITDA per share growth rate.

During the past 13 years, the highest 3-Year average EBITDA Per Share Growth Rate of Karyopharm Therapeutics was 38.20% per year. The lowest was -32.40% per year. And the median was 11.35% per year.


Karyopharm Therapeutics  (NAS:KPTI) 5-Year EBITDA Growth Rate Explanation

EBITDA per Share is the amount of Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) per outstanding share of the company's stock.

Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) is what the company earns before it expenses interest, taxes, depreciation and amortization.

5-Year EBITDA Growth Rate gives an overview of the company's growth in operating profitability and is an important factor used in calculating Peter Lynch Fair Value.


Karyopharm Therapeutics 5-Year EBITDA Growth Rate Related Terms


KPTI vs ALGS, EDSA, FLNA: 5-Year EBITDA Growth Rate Comparison

For the Biotechnology subindustry, Karyopharm Therapeutics's 5-Year EBITDA Growth Rate, along with its competitors' market caps and 5-Year EBITDA Growth Rate data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Karyopharm Therapeutics 5-Year EBITDA Growth Rate vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Karyopharm Therapeutics's 5-Year EBITDA Growth Rate distribution charts can be found below:

* The bar in red indicates where Karyopharm Therapeutics's 5-Year EBITDA Growth Rate falls into.


KPTI
45GF Score
Karyopharm Therapeutics Inc KPTI
5-Year EBITDA Growth Rate is just one metric. See GF Score™, valuation, warning signs, and more.
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Karyopharm Therapeutics 5-Year EBITDA Growth Rate Calculation

This is the 5-year average growth rate of EBITDA per Share. The growth rate is calculated with least square regression.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average EBITDA per share growth rate.

What does a 5-Year EBITDA Growth Rate of 23.80% mean?
Karyopharm Therapeutics (KPTI) has a 5-Year EBITDA Growth Rate of 23.80% as of Jun. 2026. 5-Year EBITDA Growth Rate is the 5-year average growth rate of EBITDA per share. View historical data for Karyopharm Therapeutics and its competitors.
Is Karyopharm Therapeutics' 5-Year EBITDA Growth Rate too high?
Karyopharm Therapeutics' current 5-Year EBITDA Growth Rate is 23.80%. Overall, Karyopharm Therapeutics has a GF Score™ of 45/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Karyopharm Therapeutics' 5-Year EBITDA Growth Rate compare to ALGS and EDSA?
Karyopharm Therapeutics' 5-Year EBITDA Growth Rate of 23.80% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 5-Year EBITDA Growth Rate for a Biotechnology company?
A good 5-Year EBITDA Growth Rate depends on the Biotechnology industry context. However, 5-Year EBITDA Growth Rate should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 5-Year EBITDA Growth Rate mean?
A high 5-Year EBITDA Growth Rate can signal that a stock is expensive relative to its fundamentals. 5-Year EBITDA Growth Rate is the 5-year average growth rate of EBITDA per share. View historical data for Karyopharm Therapeutics and its competitors. Karyopharm Therapeutics's current 5-Year EBITDA Growth Rate is 23.80%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Karyopharm Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Karyopharm Therapeutics (KPTI) is currently considered Possible Value Trap. The stock's GF Value™ is $4.58, compared to a current price of $1.68 — trading 63.3% below its estimated fair value. The current 5-Year EBITDA Growth Rate is 23.80%. Karyopharm Therapeutics' overall GF Score™ is 45/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 5-Year EBITDA Growth Rate calculated?
5-Year EBITDA Growth Rate is calculated from a company's financial statements. For Karyopharm Therapeutics (KPTI), the current 5-Year EBITDA Growth Rate is 23.80% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Karyopharm Therapeutics (KPTI) Overvalued in 2026?

Based on GuruFocus' analysis, Karyopharm Therapeutics stock appears to be undervalued. The current stock price of $1.68 is trading 63.3% below its estimated GF Value™ of $4.58. GuruFocus considers Karyopharm Therapeutics to be Possible Value Trap.

Key valuation signals for KPTI:

  • 5-Year EBITDA Growth Rate: 23.80%
  • GF Value™: $4.58 vs. price of $1.68 (63.3% below fair value)
  • GF Score™: 45/100 with 6 warning signs

No single metric tells the full story. See the KPTI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Karyopharm Therapeutics Business Description

Other Exchanges 25K0:Germany
Address 85 Wells Avenue, 2nd Floor, Newton, MA, USA, 02459
Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company focused on novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company conducts research focused on intracellular communication between the nucleus and cytoplasm and has developed small-molecule compounds that inhibit exportin 1 (XPO1), a nuclear export protein. It is focused on marketing XPOVIO (selinexor).
45GF Score

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5-Year EBITDA Growth Rate is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.68
Price
$4.58
GF Value