KPTI (Karyopharm Therapeutics) Institutional Ownership: 82.46% (As of Jul. 26, 2026)

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KPTI Karyopharm Therapeutics Inc KPTI
56 GF Score
Price $7.41
GF Value $6.01
Valuation Modestly Overvalued
! 6 Warning Signs
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What is Karyopharm Therapeutics Institutional Ownership?

Karyopharm Therapeutics KPTI +4.37% 56 Institutional Ownership is 82.46% as of Jul. 26, 2026. GuruFocus rates KPTI with a GF Score™ of 56/100 and a GF Value™ of $6.01 (Modestly Overvalued). The stock has 6 warning signs investors should review.

Institutional ownership is the percentage of shares that are owned by institutions out of the total shares outstanding. As of today, Karyopharm Therapeutics's institutional ownership is 82.46%.

Insider Ownership is the percentage of shares that are owned by company insiders relative to the total shares outstanding. As of today, Karyopharm Therapeutics's Insider Ownership is 15.45%.

Float Percentage Of Total Shares Outstanding is the percentage of float shares relative to the total shares outstanding. As of today, Karyopharm Therapeutics's Float Percentage Of Total Shares Outstanding is 99.51%.

Karyopharm Therapeutics Institutional Ownership Historical Data

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The historical data trend for Karyopharm Therapeutics's Institutional Ownership can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Karyopharm Therapeutics Institutional Ownership Chart

Karyopharm Therapeutics Historical Data

The historical data trend for Karyopharm Therapeutics can be seen below:

2025-09-30 2025-10-31 2025-11-30 2025-12-31 2026-01-31 2026-02-28 2026-03-31 2026-04-30 2026-05-31 2026-06-30
Institutional Ownership 20.06 13.19 12.97 14.89 16.68 16.82 15.07 13.55 13.45 20.32
KPTI
56GF Score
Karyopharm Therapeutics Inc KPTI
Institutional Ownership is just one metric. See GF Score™, valuation, warning signs, and more.
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Karyopharm Therapeutics Institutional Ownership Calculation

The percentage of shares that are owned by institutions out of the total shares outstanding.

What does a Institutional Ownership of 82.46% mean?
Karyopharm Therapeutics (KPTI) has a Institutional Ownership of 82.46% as of Jul. 26, 2026. Institutional ownership equals the percent of shares owned by financial institutions relative to total shares. View historical data on Karyopharm Therapeutics and its competitors.
Is Karyopharm Therapeutics' Institutional Ownership too high?
Karyopharm Therapeutics' current Institutional Ownership is 82.46%. Overall, Karyopharm Therapeutics has a GF Score™ of 56/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Karyopharm Therapeutics' Institutional Ownership compare to CHRS and TARA?
Karyopharm Therapeutics' Institutional Ownership of 82.46% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Institutional Ownership for a Biotechnology company?
A good Institutional Ownership depends on the Biotechnology industry context. However, Institutional Ownership should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Institutional Ownership mean?
A high Institutional Ownership can signal that a stock is expensive relative to its fundamentals. Institutional ownership equals the percent of shares owned by financial institutions relative to total shares. View historical data on Karyopharm Therapeutics and its competitors. Karyopharm Therapeutics's current Institutional Ownership is 82.46%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Karyopharm Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Karyopharm Therapeutics (KPTI) is currently considered Modestly Overvalued. The stock's GF Value™ is $6.01, compared to a current price of $7.41 — trading 23.2% above its estimated fair value. The current Institutional Ownership is 82.46%. Karyopharm Therapeutics' overall GF Score™ is 56/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Institutional Ownership calculated?
Institutional Ownership is calculated from a company's financial statements. For Karyopharm Therapeutics (KPTI), the current Institutional Ownership is 82.46% as of Jul. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Karyopharm Therapeutics (KPTI) Overvalued in 2026?

Based on GuruFocus' analysis, Karyopharm Therapeutics stock appears to be overvalued. The current stock price of $7.41 is trading 23.2% above its estimated GF Value™ of $6.01. GuruFocus considers Karyopharm Therapeutics to be Modestly Overvalued.

Key valuation signals for KPTI:

  • Institutional Ownership: 82.46%
  • GF Value™: $6.01 vs. price of $7.41 (23.2% above fair value)
  • GF Score™: 56/100 with 6 warning signs

No single metric tells the full story. See the KPTI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Karyopharm Therapeutics Business Description

Other Exchanges 25K0:Germany
Address 85 Wells Avenue, 2nd Floor, Newton, MA, USA, 02459
Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company focused on novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company conducts research focused on intracellular communication between the nucleus and cytoplasm and has developed small-molecule compounds that inhibit exportin 1 (XPO1), a nuclear export protein. It is focused on marketing XPOVIO (selinexor).
56GF Score

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Institutional Ownership is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$7.41
Price
$6.01
GF Value