STOK (Stoke Therapeutics) EV-to-EBIT: -7.84 (As of Jul. 21, 2026)

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STOK Stoke Therapeutics Inc STOK
45 GF Score
Price $28.82
GF Value $10.06
Valuation Significantly Overvalued
! 5 Warning Signs
View Full Analysis

What is Stoke Therapeutics EV-to-EBIT?

Stoke Therapeutics STOK +4.12% 45 EV-to-EBIT is -7.84 as of Jul. 21, 2026. GuruFocus rates STOK with a GF Score™ of 45/100 and a GF Value™ of $10.06 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 374 Biotechnology companies, Stoke Therapeutics ranks worse than 267379.41% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Stoke Therapeutics's Enterprise Value is $1,453.22 Mil. Stoke Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-185.25 Mil. Therefore, Stoke Therapeutics's EV-to-EBIT for today is -7.84.

The historical rank and industry rank for Stoke Therapeutics's EV-to-EBIT or its related term are showing as below:

STOK' s EV-to-EBIT Range Over the Past 10 Years
Min: -96.03   Med: -2.28   Max: 63.24
Current: -7.84

During the past 9 years, the highest EV-to-EBIT of Stoke Therapeutics was 63.24. The lowest was -96.03. And the median was -2.28.

STOK's EV-to-EBIT is ranked worse than
100% of 374 companies
in the Biotechnology industry
Industry Median: 12.865 vs STOK: -7.84

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Stoke Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $1,685.42 Mil. Stoke Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-185.25 Mil. Stoke Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -10.99%.


Stoke Therapeutics  (NAS:STOK) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Stoke Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Mar. 2026 ) =EBIT / Enterprise Value (Q: Mar. 2026 )
=-185.248/1685.4224
=-10.99 %

Stoke Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $1,685.42 Mil.
Stoke Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-185.25 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Stoke Therapeutics EV-to-EBIT Related Terms


Stoke Therapeutics EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Stoke Therapeutics's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Stoke Therapeutics EV-to-EBIT Chart

Stoke Therapeutics Annual Data
Trend Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial Premium Member Only -7.75 -1.31 -0.37 -3.76 -77.15

Stoke Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.21 9.33 38.61 -77.15 -9.10

STOK vs VRDN, ZLAB, NUVB: EV-to-EBIT Comparison

For the Biotechnology subindustry, Stoke Therapeutics's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Stoke Therapeutics EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Stoke Therapeutics's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Stoke Therapeutics's EV-to-EBIT falls into.


STOK
45GF Score
Stoke Therapeutics Inc STOK
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Stoke Therapeutics EV-to-EBIT Calculation

Stoke Therapeutics's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=1453.224/-185.248
=-7.84

Stoke Therapeutics's current Enterprise Value is $1,453.22 Mil.
Stoke Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-185.25 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of -7.84 mean?
Stoke Therapeutics (STOK) has a EV-to-EBIT of -7.84 as of Jul. 21, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Stoke Therapeutics and its competitors. According to the industry distribution chart, Stoke Therapeutics ranks #999999 out of 374 companies in the Biotechnology industry.
Is Stoke Therapeutics' EV-to-EBIT too high?
Stoke Therapeutics' current EV-to-EBIT is -7.84. Based on the distribution chart, Stoke Therapeutics ranks #999999 out of 374 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Stoke Therapeutics has a GF Score™ of 45/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Stoke Therapeutics' EV-to-EBIT compare to VRDN and ZLAB?
According to the Biotechnology industry distribution chart, Stoke Therapeutics ranks #999999 out of 374 companies for EV-to-EBIT. This places Stoke Therapeutics in the lower half of its industry. The industry median EV-to-EBIT is 12.87. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 12.87, based on 374 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Stoke Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 12.87 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Stoke Therapeutics's current EV-to-EBIT is -7.84. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Stoke Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Stoke Therapeutics (STOK) is currently considered Significantly Overvalued. The stock's GF Value™ is $10.06, compared to a current price of $28.82 — trading 186.5% above its estimated fair value. The current EV-to-EBIT is -7.84. Stoke Therapeutics' overall GF Score™ is 45/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Stoke Therapeutics (STOK), the current EV-to-EBIT is -7.84 as of Jul. 21, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Stoke Therapeutics (STOK) Overvalued in 2026?

Based on GuruFocus' analysis, Stoke Therapeutics stock appears to be overvalued. The current stock price of $28.82 is trading 186.5% above its estimated GF Value™ of $10.06. GuruFocus considers Stoke Therapeutics to be Significantly Overvalued.

Key valuation signals for STOK:

  • EV-to-EBIT: -7.84
  • GF Value™: $10.06 vs. price of $28.82 (186.5% above fair value)
  • GF Score™: 45/100 with 5 warning signs

No single metric tells the full story. See the STOK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Stoke Therapeutics Business Description

Other Exchanges 0GT:Germany
Address 45 Wiggins Avenue, Bedford, MA, USA, 01730
Stoke Therapeutics Inc is a biotechnology company dedicated to restoring protein expression by harnessing the bodys potential with RNA medicine. Its proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to restore naturally-occurring protein levels selectively. Its first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome. The company provides early programs focused on multiple targets, including haploinsufficiency diseases of the central nervous system and eye, to up-regulate the protein expression of the underlying disease gene in a mutation-agnostic manner.
45GF Score

Get the complete analysis for STOK

EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$28.82
Price
$10.06
GF Value