Stoke TherapeuticsSTOK +5.09%45 Altman Z-Score is 22.58 as of Jun. 27, 2026, which is 496% above its 10-year median of 3.79. GuruFocus rates STOK with a GF Score™ of 45/100 and a GF Value™ of $10.16 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 934 Biotechnology companies, Stoke Therapeutics ranks better than 88.65% on this metric.
The Altman Z-Score is a model designed to predict the likelihood of a company going bankrupt within the next two years. Created by American finance professor Edward Altman in 1968, the model is specifically designed for publicly traded manufacturing companies with assets greater than $1 million.
Good Sign:
Altman Z-score of 21.46 is strong.
Stoke Therapeutics has a Altman Z-Score of 22.58, indicating it is in Safe Zones. This implies the Altman Z-Score is strong.
The zones of discrimination were as such:
When Altman Z-Score <= 1.8, it is in Distress Zones.
When Altman Z-Score >= 3, it is in Safe Zones.
When Altman Z-Score is between 1.8 and 3, it is in Grey Zones.
The historical rank and industry rank for Stoke Therapeutics's Altman Z-Score or its related term are showing as below:
STOK'
s Altman Z-Score Range Over the Past 10 Years
Min: -0.98 Med: 3.79 Max: 23.07
Current: 21.46
During the past 9 years, Stoke Therapeutics's highest Altman Z-Score was 23.07. The lowest was -0.98. And the median was 3.79.
X1: The Working Capital/Total Assets (WC/TA) ratio is a measure of the net liquid assets of the firm relative to the total capitalization. Working capital is defined as the difference between current assets and current liabilities. Ordinarily, a firm experiencing consistent operating losses will have shrinking current assets in relation to total assets. Altman found this one proved to be the most valuable liquidity ratio comparing with the current ratio and the quick ratio. This is however the least significant of the five factors.
X2: Retained Earnings/Total Assets: the RE/TA ratio measures the leverage of a firm. Retained earnings is the account which reports the total amount of reinvested earnings and/or losses of a firm over its entire life. Those firms with high RE, relative to TA, have financed their assets through retention of profits and have not utilized as much debt.
X3, Earnings Before Interest and Taxes/Total Assets (EBIT/TA): This ratio is a measure of the true productivity of the firm's assets, independent of any tax or leverage factors. Since a firm's ultimate existence is based on the earning power of its assets, this ratio appears to be particularly appropriate for studies dealing with corporate failure. This ratio continually outperforms other profitability measures, including cash flow.
X4, Market Value of Equity/Book Value of Total Liabilities (MVE/TL): The measure shows how much the firm's assets can decline in value (measured by market value of equity plus debt) before the liabilities exceed the assets and the firm becomes insolvent.
X5, Revenue/Total Assets (S/TA): The capital-turnover ratio is a standard financial ratio illustrating the sales generating ability of the firm's assets.
Altman Z-Score does not apply to financial companies.
Stoke Therapeutics Altman Z-Score Related Terms
Stoke Therapeutics Altman Z-Score Historical Data
* Premium members only.
The historical data trend for Stoke Therapeutics's Altman Z-Score can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
STOK vs SION, RXRX, VRDN: Altman Z-Score Comparison
For the Biotechnology subindustry, Stoke Therapeutics's Altman Z-Score, along with its competitors' market caps and Altman Z-Score data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Stoke Therapeutics Altman Z-Score vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Stoke Therapeutics's Altman Z-Score distribution charts can be found below:
* The bar in red indicates where Stoke Therapeutics's Altman Z-Score falls into.
Altman Z-Score model is an accurate forecaster of failure up to two years prior to distress. It can be considered the assessment of the distress of industrial corporations.
Stoke Therapeutics's Altman Z-Score for today is calculated with this formula:
Z
=
1.2
*
X1
+
1.4
*
X2
+
3.3
*
X3
+
0.6
*
X4
+
1.0
*
X5
=
1.2
*
0.7351
+
1.4
*
-1.2356
+
3.3
*
-0.3859
+
0.6
*
41.0493
+
1.0
*
0.0724
=
22.58
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency. GuruFocus does not calculate Altman Z-Score when X4 or X5 value is 0.
Stoke Therapeutics (STOK) has a Altman Z-Score of 22.58 as of Jun. 27, 2026. The Altman Z-score measures a company's bankruptcy risk. View historical data on Stoke Therapeutics and its competitors. This is 496% above median its historical median of 3.79. According to the industry distribution chart, Stoke Therapeutics ranks #106 out of 934 companies in the Biotechnology industry, placing it in the top 11.3%.
Is Stoke Therapeutics' Altman Z-Score too high?
Stoke Therapeutics' current Altman Z-Score of 22.58 is 496% above median its 10-year median of 3.79. The Biotechnology industry median Altman Z-Score is 2.63. Stoke Therapeutics' value of 22.58 is 760.2% above this industry median. Based on the distribution chart, Stoke Therapeutics ranks #106 out of 934 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Stoke Therapeutics has a GF Score™ of 45/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Stoke Therapeutics' Altman Z-Score compare to SION and RXRX?
According to the Biotechnology industry distribution chart, Stoke Therapeutics ranks #106 out of 934 companies for Altman Z-Score. This places Stoke Therapeutics in the top 11% of its industry — outperforming the majority of peers. The industry median Altman Z-Score is 2.63. Stoke Therapeutics' value of 22.58 is 760.2% above this benchmark. While the company's 10-year median is 3.79 vs. the industry median of 2.63, Stoke Therapeutics has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Altman Z-Score for a Biotechnology company?
The median Altman Z-Score among Biotechnology companies is 2.63, based on 934 companies in the industry. Companies in the top quartile (top 25%) have a Altman Z-Score significantly above this median, while those in the bottom quartile fall well below. However, Altman Z-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Stoke Therapeutics's current Altman Z-Score of 22.58 is 760.2% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Altman Z-Score mean?
A high Altman Z-Score can signal that a stock is expensive relative to its fundamentals. The Altman Z-score measures a company's bankruptcy risk. View historical data on Stoke Therapeutics and its competitors. For the Biotechnology industry, the median Altman Z-Score is 2.63 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Stoke Therapeutics's current Altman Z-Score is 22.58, which is 496% above median its own 10-year median of 3.79. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Stoke Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Stoke Therapeutics (STOK) is currently considered Significantly Overvalued. The stock's GF Value™ is $10.16, compared to a current price of $31.90 — trading 214% above its estimated fair value. The current Altman Z-Score is 22.58, which is 496% above median its 10-year median of 3.79 and 760.2% above the Biotechnology industry median of 2.63. Stoke Therapeutics' overall GF Score™ is 45/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Altman Z-Score calculated?
Altman Z-Score is calculated from a company's financial statements. For Stoke Therapeutics (STOK), the current Altman Z-Score is 22.58 as of Jun. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Stoke Therapeutics (STOK) Overvalued in 2026?
Based on GuruFocus' analysis, Stoke Therapeutics stock appears to be overvalued.
The current stock price of $31.90 is trading 214% above its estimated GF Value™ of $10.16.
GuruFocus considers Stoke Therapeutics to be Significantly Overvalued.
Key valuation signals for STOK:
Altman Z-Score: 22.58 (496% above median its 10-year median of 3.79)
GF Value™: $10.16 vs. price of $31.90 (214% above fair value)
Industry Position: 760.2% above the Biotechnology median (#106 of 934)
No single metric tells the full story. See the STOK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Stoke Therapeutics Inc is a biotechnology company dedicated to restoring protein expression by harnessing the bodys potential with RNA medicine. Its proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to restore naturally-occurring protein levels selectively. Its first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome. The company provides early programs focused on multiple targets, including haploinsufficiency diseases of the central nervous system and eye, to up-regulate the protein expression of the underlying disease gene in a mutation-agnostic manner.
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