STOK (Stoke Therapeutics) Pre-Tax Income: $-209.18 Mil (TTM As of Jun. 2026)

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STOK Stoke Therapeutics Inc STOK
44 GF Score
Price $29.03
GF Value $9.85
Valuation Significantly Overvalued
! 5 Warning Signs
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What is Stoke Therapeutics Pre-Tax Income?

Stoke Therapeutics STOK -1.16% 44 Pre-Tax Income is $-209.18 Mil as of Jun. 2026. GuruFocus rates STOK with a GF Score™ of 44/100 and a GF Value™ of $9.85 (Significantly Overvalued). The stock has 5 warning signs investors should review.

Pretax income is the income that a company earns before paying income taxes. Stoke Therapeutics's pretax income for the three months ended in Jun. 2026 was $-61.62 Mil. Its pretax income for the trailing twelve months (TTM) ended in Jun. 2026 was $-209.18 Mil. Stoke Therapeutics's pretax margin was -660.78%.

During the past 9 years, Stoke Therapeutics's highest Pretax Margin was -3.73%. The lowest was -1192.47%. And the median was -529.08%.


Stoke Therapeutics  (NAS:STOK) Pre-Tax Income Explanation

Stoke Therapeutics's Pretax Margin for the quarter that ended in Jun. 2026 is calculated as

Pretax Margin=Pretax Income/Revenue
=-61.618/9.325
=-660.78%

During the past 9 years, Stoke Therapeutics's highest Pretax Margin was -3.73%. The lowest was -1192.47%. And the median was -529.08%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Stoke Therapeutics Pre-Tax Income Related Terms


Stoke Therapeutics Pre-Tax Income Historical Data

* Premium members only.

The historical data trend for Stoke Therapeutics's Pre-Tax Income can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Stoke Therapeutics Pre-Tax Income Chart

Stoke Therapeutics Annual Data
Trend Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pre-Tax Income
Get a 7-Day Free Trial Premium Member Only -85.81 -101.07 -104.70 -88.98 -6.89

Stoke Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Pre-Tax Income Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -23.48 -39.63 -57.93 -50.00 -61.62

STOK vs ZBIO, ZYME, COAG: Pre-Tax Income Comparison

For the Biotechnology subindustry, Stoke Therapeutics's Pre-Tax Income, along with its competitors' market caps and Pre-Tax Income data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Stoke Therapeutics Pre-Tax Income vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Stoke Therapeutics's Pre-Tax Income distribution charts can be found below:

* The bar in red indicates where Stoke Therapeutics's Pre-Tax Income falls into.


STOK
44GF Score
Stoke Therapeutics Inc STOK
Pre-Tax Income is just one metric. See GF Score™, valuation, warning signs, and more.
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Stoke Therapeutics Pre-Tax Income Calculation

This is the income that a company earns before paying income taxes.

Stoke Therapeutics's Pretax Income for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Income=Operating Income+Non Operating Income+Interest Expense+Interest Income+Other
=-20.59+-0.051+0+0+13.756
=-6.89

Stoke Therapeutics's Pretax Income for the quarter that ended in Jun. 2026 is calculated as

Pretax Income=Operating Income+Non Operating Income+Interest Expense+Interest Income+Other
=-65.429+0.308+0+0+3.503
=-61.62

Pre-Tax Income for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-209.18 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pre-Tax Income →
What does a Pre-Tax Income of $-209.18 Mil mean?
Stoke Therapeutics (STOK) has a Pre-Tax Income of $-209.18 Mil as of Jun. 2026. Pre-Tax Income is the total earnings before taxes but after all operating and interest expenses. View historical data on Stoke Therapeutics and its competitors.
Is Stoke Therapeutics' Pre-Tax Income too high?
Stoke Therapeutics' current Pre-Tax Income is $-209.18 Mil. Overall, Stoke Therapeutics has a GF Score™ of 44/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Stoke Therapeutics' Pre-Tax Income compare to ZBIO and ZYME?
Stoke Therapeutics' Pre-Tax Income of $-209.18 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pre-Tax Income for a Biotechnology company?
A good Pre-Tax Income depends on the Biotechnology industry context. However, Pre-Tax Income should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pre-Tax Income mean?
A high Pre-Tax Income can signal that a stock is expensive relative to its fundamentals. Pre-Tax Income is the total earnings before taxes but after all operating and interest expenses. View historical data on Stoke Therapeutics and its competitors. Stoke Therapeutics's current Pre-Tax Income is $-209.18 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Stoke Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Stoke Therapeutics (STOK) is currently considered Significantly Overvalued. The stock's GF Value™ is $9.85, compared to a current price of $29.03 — trading 194.7% above its estimated fair value. The current Pre-Tax Income is $-209.18 Mil. Stoke Therapeutics' overall GF Score™ is 44/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pre-Tax Income calculated?
Pre-Tax Income is calculated from a company's financial statements. For Stoke Therapeutics (STOK), the current Pre-Tax Income is $-209.18 Mil as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Stoke Therapeutics (STOK) Overvalued in 2026?

Based on GuruFocus' analysis, Stoke Therapeutics stock appears to be overvalued. The current stock price of $29.03 is trading 194.7% above its estimated GF Value™ of $9.85. GuruFocus considers Stoke Therapeutics to be Significantly Overvalued.

Key valuation signals for STOK:

  • Pre-Tax Income: $-209.18 Mil
  • GF Value™: $9.85 vs. price of $29.03 (194.7% above fair value)
  • GF Score™: 44/100 with 5 warning signs

No single metric tells the full story. See the STOK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Stoke Therapeutics Business Description

Other Exchanges 0GT:Germany
Address 45 Wiggins Avenue, Bedford, MA, USA, 01730
Stoke Therapeutics Inc is a biotechnology company dedicated to restoring protein expression by harnessing the bodys potential with RNA medicine. Its proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to restore naturally-occurring protein levels selectively. Its first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome. The company provides early programs focused on multiple targets, including haploinsufficiency diseases of the central nervous system and eye, to up-regulate the protein expression of the underlying disease gene in a mutation-agnostic manner.
44GF Score

Get the complete analysis for STOK

Pre-Tax Income is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$29.03
Price
$9.85
GF Value