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Richard Sloan from the University of Michigan was first to document what is referred to as the "accrual anomaly". His 1996 paper found that shares of companies with small or negative accruals vastly outperform (+10%) those of companies with large ones.
Stoke Therapeutics's Sloan Ratio for the quarter that ended in Mar. 2026 was 28.61%.
Warning Sign:
When sloan ratio (32.11)% higher than 25% or lower than -25%, earnings are more likely to be made up of accruals.
As of Mar. 2026, Stoke Therapeutics has a Sloan Ratio of 28.61%, indicating earnings are more likely to be made up of accruals.
Stoke Therapeutics (NAS:STOK) Sloan Ratio % Explanation
A former University of Michigan researcher, Richard Sloan's 1996 paper found that shares of companies with small or negative accruals vastly outperform (+10%) those of companies with large ones. In fact, for the 40-year period between 1962 and 2001, buying the lowest accrual companies and shorting the highest accrual companies resulted in an average annual compounded return of 18%, more than double the S&P 500's 7.4% annual return over the same period.
If the Sloan Ratio is between -10% and 10%, the company is in the safe zone and there is no funny business with accruals.
If the Sloan Ratio is less than between -25% and -10% on the negative side, and between 10% and 25% on the positive side, this is a warning stage of accrual build up.
If the Sloan Ratio is less than -25% or greater than 25%, and this ratio is consistent over several quarters or even years, be careful. Earnings are highly likely to be made up of accruals.
As of Mar. 2026, Stoke Therapeutics has a Sloan Ratio of 28.61%, indicating earnings are more likely to be made up of accruals.
Stoke Therapeutics Sloan Ratio % Related Terms
Stoke Therapeutics Sloan Ratio % Historical Data
* Premium members only.
The historical data trend for Stoke Therapeutics's Sloan Ratio % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
STOK vs VRDN, ZLAB, NUVB: Sloan Ratio % Comparison
For the Biotechnology subindustry, Stoke Therapeutics's Sloan Ratio %, along with its competitors' market caps and Sloan Ratio % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Stoke Therapeutics Sloan Ratio % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Stoke Therapeutics's Sloan Ratio % distribution charts can be found below:
* The bar in red indicates where Stoke Therapeutics's Sloan Ratio % falls into.
Earnings contain a lot of non cash earnings which is called accruals. The Sloan ratio is a way to identify firms with low non-cash or accrual-derived earnings relative to their cash flow.
Stoke Therapeutics's Sloan Ratio for the fiscal year that ended in Dec. 2025 is calculated as
Stoke Therapeutics's Net Income for the trailing twelve months (TTM) ended in Mar. 2026 was -23.483 (Jun. 2025 ) + -38.347 (Sep. 2025 ) + -57.934 (Dec. 2025 ) + -50.003 (Mar. 2026 ) = $-169.77 Mil.
Stoke Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was -25.422 (Jun. 2025 ) + -30.366 (Sep. 2025 ) + -30.454 (Dec. 2025 ) + -60.582 (Mar. 2026 ) = $-146.82 Mil.
Stoke Therapeutics's Cash Flow from Investing for the trailing twelve months (TTM) ended in Mar. 2026 was -148.477 (Jun. 2025 ) + 9.094 (Sep. 2025 ) + -61.061 (Dec. 2025 ) + 50.694 (Mar. 2026 ) = $-149.75 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Stoke Therapeutics (STOK) has a Sloan Ratio % of 28.61% as of Mar. 2026. Sloan ratio measures earnings quality based on the amount of accruals. View historical data on Stoke Therapeutics and its competitors.
Is Stoke Therapeutics' Sloan Ratio % too high?
Stoke Therapeutics' current Sloan Ratio % is 28.61%. Overall, Stoke Therapeutics has a GF Score™ of 45/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Stoke Therapeutics' Sloan Ratio % compare to VRDN and ZLAB?
Stoke Therapeutics' Sloan Ratio % of 28.61% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Sloan Ratio % for a Biotechnology company?
A good Sloan Ratio % depends on the Biotechnology industry context. However, Sloan Ratio % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Sloan Ratio % mean?
A high Sloan Ratio % can signal that a stock is expensive relative to its fundamentals. Sloan ratio measures earnings quality based on the amount of accruals. View historical data on Stoke Therapeutics and its competitors. Stoke Therapeutics's current Sloan Ratio % is 28.61%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Stoke Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Stoke Therapeutics (STOK) is currently considered Significantly Overvalued. The stock's GF Value™ is $10.06, compared to a current price of $28.96 — trading 187.9% above its estimated fair value. The current Sloan Ratio % is 28.61%. Stoke Therapeutics' overall GF Score™ is 45/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Sloan Ratio % calculated?
Sloan Ratio % is calculated from a company's financial statements. For Stoke Therapeutics (STOK), the current Sloan Ratio % is 28.61% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Stoke Therapeutics (STOK) Overvalued in 2026?
Based on GuruFocus' analysis, Stoke Therapeutics stock appears to be overvalued.
The current stock price of $28.96 is trading 187.9% above its estimated GF Value™ of $10.06.
GuruFocus considers Stoke Therapeutics to be Significantly Overvalued.
Key valuation signals for STOK:
Sloan Ratio %: 28.61%
GF Value™: $10.06 vs. price of $28.96 (187.9% above fair value)
No single metric tells the full story. See the STOK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Stoke Therapeutics Inc is a biotechnology company dedicated to restoring protein expression by harnessing the bodys potential with RNA medicine. Its proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to restore naturally-occurring protein levels selectively. Its first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome. The company provides early programs focused on multiple targets, including haploinsufficiency diseases of the central nervous system and eye, to up-regulate the protein expression of the underlying disease gene in a mutation-agnostic manner.
45GF Score
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